Extrait

Background and study aims Acute kidney injury, where the kidneys suddenly become unable to function properly, is a serious complication that can occur during hip fracture surgery in the elderly. This could be due to a number of factors, and this study aims to see whether it may be due to poor fluid intake by the patient (preoperative dehydration) and the choice of infusion fluid (crystalloid or hyperoncotic colloid) used during the operation. Who can participate? Adults aged between 70-90 years with a hip fracture and scheduled for surgery. What does the study involve? Each patient is randomly chosen to receive either crystalloid or hyperoncotic colloid at the start of the operation. Urine and blood samples will also be taken three times during the course of the day of the surgery. What are the possible benefits and risks of participating? All patients will benefit from having their blood circulation monitored using a non-invasive apparatus called the Nexfin. Hyperoncotic colloid can cause fluid to collect in the lungs of susceptible patients, but this is minimized by giving only a small amount of the fluid and also by doing so at the point when the anaesthesia is given; this causes the blood vessels to widen (vasodilation) Where is the study run from? Södertälje Hospital (Sweden) When is study starting and how long is it expected to run for? September 2014 to September 2015 Who is funding the study? Stockholm County Council (Sweden) Who is the main contact? Professor Robert Hahn [email protected]

Critère d'inclusion

• Hip Fracture Surgery

Liens

• ictrp
• isrctn