Acute Graft Versus Host Disease Clinical Trials

96 clinical trials for Acute Graft Versus Host Disease across international registries, including 15 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Dental Cleaning to Prevent Chronic Graft-Versus-Host Disease — RECRUITING · NA
• Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies — RECRUITING · PHASE1
• FMT in Gut aGVHD Treated — RECRUITING
• Moxibustion for Steroid-Refractory Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation — RECRUITING · PHASE2
• MAGIC Ruxolitinib for aGVHD — RECRUITING · PHASE2
• A Phase Ib Clinical Study of AC-003 Capsules in Subjects With aGVHD. — RECRUITING · PHASE1
• Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial — RECRUITING · NA
• Effect of Stem Cell Infusion Time on aGVHD in Patients With Hematological Malignancies Post UCBT — RECRUITING · PHASE3
• First-Line Jaktinib for Acute Graft-Versus-Host Disease (aGVHD) — RECRUITING · PHASE1
• Anti-CD25 rhMAb for aGVHD Prevention in High-Risk Adults Using the daGOAT Model — RECRUITING · PHASE2
• Effect of Stem Cell Infusion Time on aGVHD in Patients With Nonmalignant Hematologic Diseases — RECRUITING · PHASE3
• Mini-dose MTX Plus Standard-dose Steroid for the Initial Treatment of Acute GVHD — RECRUITING · PHASE3
• Efficacy of Human Chorionic Gonadotropin in Acute GVHD Treatment — RECRUITING · PHASE2
• Universal CNK-UT Therapy for Refractory aGVHD — RECRUITING · PHASE1
• Tissue-resident Immune Cell Subsets in aGVHD — RECRUITING
• Fecal Microbiota Transplantation for the Prevention of Acute Graft Versus Host Disease in Adults Undergoing Allogeneic Hematopoietic Cell Transplantation — ACTIVE_NOT_RECRUITING · PHASE2
• Steroids Combined With Ruxolitinib as First-Line Therapy for Grade II Acute Graft-versus-Host Disease — ACTIVE_NOT_RECRUITING · PHASE1
• A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD — COMPLETED · PHASE1
• Abatacept s.c. for aGVHD Prevention in Haplo-HCT — COMPLETED · PHASE1
• The Safety and Efficacy of Alpha-1 Antitrypsin (AAT) for the Prevention of Graft-versus-host Disease (GVHD) in Patients Receiving Hematopoietic Cell Transplant — COMPLETED · PHASE2
• hAESCs Prevent Acute Graft-versus-host Disease After Hematopoietic Stem Cell Transplantation — WITHDRAWN · PHASE1
• Ruxolitinib, Human Chorionic Gonadotropin (uhCG/EGF), and Dose De-escalated Corticosteroids — TERMINATED · PHASE1
• Dendritic Cells in Patients With Acute or Chronic Skin Graft Versus Host Disease — ACTIVE_NOT_RECRUITING
• Evaluation of Umbilical Cord-Derived Wharton's Jelly Stem Cells for the Treatment of Acute Graft Versus Host Disease — COMPLETED · PHASE1
• Sitagliptin for Prevention of aGVHD After Alternative Donor Transplation — COMPLETED · PHASE3
• Phase 2 Open Label Prospective Dose-Ranging Clinical Trial with Escalation and Expansion Cohorts to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Dosing, and Efficacy of RLS-0071 for the Treatment of Hospitalized Patients with Steroid -Refractory Acute Graft-versus-Host Disease — OTHER · PHASE2
• UCMSCs as Front-line Approach of Treatment for Patients With aGVHD — COMPLETED · PHASE1
• Effect of Stem Cell Infusion Time on aGVHD in Patients With Hematological Malignancies — ACTIVE_NOT_RECRUITING · PHASE3
• Safety and Efficacy of Itacitinib in Combination With Corticosteroids for Treatment of Graft-Versus-Host Disease in Pediatric Subjects — TERMINATED · PHASE1
• A Phase 2/3, Multicenter, randOmized, Double-blind, placebo-controlled, stUdy to evaLuate the safety and efficacy of Alpha-1 AntiTrypsin for the prEvention of graft versus-host disease in patients receiving hematopoietic cell transplant (MODULAATE Study) — OTHER · PHASE3
• Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant — ACTIVE_NOT_RECRUITING · PHASE3
• Clinical Observation on the Efficacy of Patient-Donor Derived Probiotics in Improving Intestinal Flora Disorder in Patients With Intestinal Acute Graft-Versus-Host Disease (aGVHD) — NOT_YET_RECRUITING · NA
• A Study of Itolizumab in Combination With Corticosteroids for the First-Line Treatment of Acute Graft Versus Host Disease (EQUATOR) — TERMINATED · PHASE3
• A Study to Assess the Safety and Pharmacokinetics of GDC-8264 in Combination With Standard of Care in Participants With Acute Graft-Versus-Host Disease (aGVHD) — COMPLETED · PHASE1
• Study of Pharmacokinetics, Activity and Safety of Ruxolitinib in Pediatric Patients With Grade II-IV Acute Graft vs. Host Disease — COMPLETED · PHASE1
• A Study of iMSC for the Prevention of Acute Graft-versus-host Disease After Allogeneic Hematopoietic Stem Cell Transplantation — NOT_YET_RECRUITING · PHASE1
• A Trial to Evaluate the Safety and Efficacy of NCR102 in Subjects With aGVHD — NOT_YET_RECRUITING · PHASE1
• Extracorporal Photopheresis With UVADEX Plus Standard Steroid Treatment for High Risk Acute Graft-versus-host Disease — ACTIVE_NOT_RECRUITING · PHASE2
• A Phase 3, Randomized, Double-Blind, Placebo-Controlled Multicenter Study of Itolizumab in Combination with Corticosteroids for the Initial Treatment of Acute Graft Versus Host Disease — OTHER · PHASE3
• Novel BET Inhibitor PLX51107 for Steroid-Refractory Acute GVHD — TERMINATED · PHASE1
• Assessment of MicroRNA Expression in Acute Graft-versus-Host Disease — COMPLETED
• A Clinical Study of Bacillus Coagulans in Acute Graft-Versus-Host Disease After Hematopoietic Stem Cell Transplantation — NOT_YET_RECRUITING · NA
• Dose-finding Study Using Pentostatin for Injection in the Treatment of Steroid-refractory aGvHD — TERMINATED · PHASE1
• Phase 2 Open Label Prospective Dose-Ranging Clinical Trial with Escalation and Expansion Cohorts to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Dosing, and Efficacy of RLS-0071 for the Treatment of Hospitalized Patients with Steroid -Refractory Acute Graft-versus-Host Disease — OTHER · PHASE2
• Low-dose Cyclophosphamide or CNI in the Prevention of Acute Graft-versus-host Disease After gDLI — NOT_YET_RECRUITING · NA
• Effectiveness and Safety of a Single-Center Clinical Study on a CD25 Monoclonal Antibody-Containing GVHD Prophylaxis Scheme to Reduce the Incidence of Severe Acute GVHD After Umbilical Cord Blood Transplantation for Malignant Hematologic Diseases — NOT_YET_RECRUITING · PHASE2
• Combination of Steroid and Humanized CD25 Monoclonal Antibody as First-line Therapy for aGVHD — OTHER · PHASE2
• RGI-2001 for the Prevention of Acute Graft-vs-Host Disease in Subjects Following Allogeneic Hematopoietic Stem Cell Transplantation — COMPLETED · PHASE2
• A randomized, single-blind trial to evaluate the safety and efficacy of apraglutide in subjects with Grade II to IV (MAGIC) steroid refractory gastrointestinal (GI) acute graft versus host disease on best available therapy. — OTHER · PHASE2
• Donor Neutrophil Subsets to Predict the Risk of aGVHD — OTHER

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