Advanced Colorectal Cancer Clinical Trials

75 clinical trials for Advanced Colorectal Cancer across international registries, including 14 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations. — RECRUITING · PHASE1
• A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer — RECRUITING · PHASE1
• Standard Second-line Therapy With ONgericimab and TOripalimab in pMMR/MSS Colorectal Cancer: a Single-arm Phase II Trial — RECRUITING · PHASE2
• Clinical Trial Evaluating the Efficacy of Capecitabine Plus Lenvatinib in Patients With Advanced Colorectal Cancer Refractory to Irinotecan, Oxaliplatin, and Fluoropyrimidine — RECRUITING · PHASE1
• Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination With Defactinib (FAK Inhibitor) and Cetuximab in Patients With Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cancer — RECRUITING · PHASE2
• Evaluation of RBS2418 in Patients With Advanced, Metastatic, and Progressive Colorectal Cancer — RECRUITING · PHASE2
• FOLICOLOR TRIAL: Following Therapy Response Through Liquid Biopsy in Metatstatic Colorectal Cancer Patients — RECRUITING · PHASE3
• TL938 and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer — RECRUITING · PHASE2
• Optimal Surveillance Strategy After Positive FIT and Negative Colonoscopy — RECRUITING
• Clinical Study on the First-line Treatment of Advanced Colorectal Cancer With Simultaneous Infusion of Levozolinate for Injection and 5-FU — RECRUITING · PHASE2
• Trial of ProAgio in Advanced/Metastatic Colorectal Cancer — RECRUITING · PHASE1
• A Phase 2 Study Evaluating the Safety and Efficacy of JS207 With or Without JS015 in Combination With Chemotherapy in Patients With Colorectal Cancer — RECRUITING · PHASE2
• The Role of 18F-FDG and 68Ga-FAPI PET/CT in the Diagnosis and the Efficacy Evaluation of Advanced Colorectal Cancer (peritoneal Metastasis With/without Other Metastases) — RECRUITING
• Chemokine and Co-stimulatory Molecule-modified Mesenchymal Stem Cells for the Treatment of Advanced Colorectal Cancer — RECRUITING · PHASE1
• Treatment Monitoring of Advanced Colorectal cancer with 18F-FDG PET/CT — COMPLETED · PHASE4
• A Study of MRG007 Combination Therapy for Advanced Colorectal Cancer — NOT_YET_RECRUITING · PHASE1
• Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10) — ACTIVE_NOT_RECRUITING · PHASE3
• A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplification — TERMINATED · PHASE1
• A Randomized, Open-Label, Controlled, Multicenter Phase III Clinical Study of SHR-A1811 in Combination With Chemotherapy and Bevacizumab Versus Standard Therapy as First-Line Treatment for Advanced Colorectal Cancer — NOT_YET_RECRUITING · PHASE3
• Sintilimab Plus Gossypol Acetate in Advanced Colorectal Cancer — NOT_YET_RECRUITING · PHASE2
• ANGIOPREDICT. ICORG 12-16, V3 — COMPLETED
• Identification of New Patient Stratification Tools in MSS RAS mt mCRC — COMPLETED
• JAB-21822 in Combination With Cetuximab in Patients With Advanced CRC and Other Solid Tumors With KRAS G12C Mutation — ACTIVE_NOT_RECRUITING · PHASE1
• Rehabilitation for People With Advanced Cancer — COMPLETED · NA
• Trastuzumab Deruxtecan in Participants With HER2-overexpressing Advanced or Metastatic Colorectal Cancer — COMPLETED · PHASE2
• Assessment of the Dose Safety and Efficacy of Serine Combined With Fluorouracil Drugs — NOT_YET_RECRUITING · PHASE1
• Injection of SHR-A1811 Versus Physician Choiced Treatment in Patients With Advanced Colorectal Cancer Who Had Failed to Respond to Oxaliplatin, 5-fu, and Irinotecan — ACTIVE_NOT_RECRUITING · PHASE3
• A Study of Cetuximabβ Combined With Envolimab and mFOLFOX6 in Subjects With Advanced Colorectal Cancer — NOT_YET_RECRUITING · PHASE2
• SBRT-LDRT-Cadonilimab for Advanced Gastric, Colorectal and Ovarian Cancers With Peritoneal Metastases — ACTIVE_NOT_RECRUITING · PHASE1
• A Multicenter, Open Phase IIb Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in the Treatment of Advanced Colorectal Cancer — NOT_YET_RECRUITING · PHASE2
• SHR-A1811 Combined with Apatinib in the Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma and Colorectal Cancer — NOT_YET_RECRUITING · PHASE2
• IMC001 for Clinical Research on Advanced Digestive System Malignancies — OTHER · PHASE1
• A Clinical Study of T3011 in Combination With Regorafenib in Patients With Advanced Colorectal Cancer — OTHER · PHASE1
• Effect of Curcumin on Dose Limiting Toxicity and Pharmacokinetics of Irinotecan in Patients With Solid Tumors — COMPLETED · PHASE1
• Cetuximab in Combination With Dabrafenib and Tislelizumab in BRAF Mutated Treatment of Advanced Colorectal Cancer — OTHER · NA
• Fruquintinib Combined With Chemotherapy as Third-line /Third-line+ Treatment in Advanced Colorectal Cancer — OTHER · NA
• Regorafenib Monotherapy as Second-line Treatment of Patients With RAS-mutant Advanced Colorectal Cancer — OTHER · PHASE2
• A Prospective Cohort Study of Advanced Colorectal Cancer Treated With Oxaliplatin and Irinotecan. — OTHER
• Circulating Tumor DNA Guided Therapeutic Strategies for CRC Patients With Small Pulmonary Nodules — OTHER · NA
• Screening Platform for Clinical Trials in Advanced Colorectal Cancer — COMPLETED
• Efficacy, Safety and Exploratory Clinical Study of Bevacizumab Combined With Oxaliplatin and TAS-102 in First-line Treatment of Advanced Colorectal Cancer — NOT_YET_RECRUITING · PHASE2
• Regorafenib Treatment Patterns and Survival Outcomes in Advanced Colorectal Cancer: A Real-world Study — OTHER
• Surufatinib Combined With Sintilimab for Advanced MSS-Type Colorectal Cancer : a Phase II Study — OTHER · PHASE2
• Trifluridine/Tipiracil Combined With Oxaliplatin and Bevacizumab Versus XELOX Plus Bevacizumab in mCRC — OTHER · PHASE2
• LEAC-102 for Advanced Colorectal Cancer — OTHER · PHASE1
• Anlotinib Combined With mXELIRI as Second-line Treatment of Advanced Colorectal Cancer — OTHER · PHASE1
• Raltitrexed-based Chemotherapy Plus Bevacizumab in Retreated Patients With Advanced Colorectal Cancer — OTHER · PHASE2
• A Study of Bevacizumab Plus XELOX/XELIRI for First-line Treatment in Unresectable Advanced Colorectal Cancer — OTHER · PHASE2
• Evaluate the Efficacy of MEDI4736 in Immunological Subsets of Advanced Colorectal Cancer — COMPLETED · PHASE2
• Surufatinib Combine With Immunotherapy and Chemotherapy for Second-line Treatment in Advanced Colorectal Cancer — OTHER · PHASE1

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