Amyotrophic Lateral Sclerosis Clinical Trials

916 clinical trials for Amyotrophic Lateral Sclerosis across international registries, including 176 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia — RECRUITING
• Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS — RECRUITING · PHASE3
• Effects of Psilocybin in Patients With Amyotrophic Lateral Sclerosis — RECRUITING · PHASE1
• Therapeutic Approach of Repeated Transient Blood-brain Barrier Opening in Amyotrophic Lateral Sclerosis. — RECRUITING · PHASE1
• Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications — RECRUITING · NA
• Study of COYA 302 for the Treatment of ALS — RECRUITING · PHASE2
• French-German Cohort Study to Determine Factors Associated With Weight Loss in Amyotrophic Lateral Sclerosis — RECRUITING · NA
• A First-in-Human, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study of Intrathecally Administered LTX-002 in Adult Participants with Amyotrophic Lateral Sclerosis — RECRUITING · PHASE2
• FUNCtion ALS: Aiming to Restore UNC13A Function in People Living With ALS — RECRUITING · PHASE1
• Oral Intake of Enteral Nutrition Formula Preceding Placement and Feeding Via GTube and Its Impact on Formula Intolerance in pALS — RECRUITING · NA
• Personalized Antisense Oligonucleotide Therapy for Participants With TARDBP ALS — RECRUITING · PHASE1
• Multicenter ALS Imaging Study — RECRUITING
• PREVENT ALL ALS Study — RECRUITING
• Lung Insufflation Capacity Training and Respiratory Function in Amyotrophic Lateral Sclerosis — RECRUITING · NA
• ASSESS ALL ALS Study — RECRUITING
• QCT in ALS Diagnosis, Mechanistic Understanding and Follow-up — RECRUITING · NA
• ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) — RECRUITING
• Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis — RECRUITING · PHASE2
• A phase 2b, randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the efficacy, safety, pharmacokinetics, and pharmacodynamics of Usnoflast administered to adult subjects with Amyotrophic Lateral Sclerosis (ALS) — RECRUITING · PHASE2
• Plasmapheresis in Amyotrophic Lateral Sclerosis With Autoantibody Against NRIP 2 (PALADIN2) — RECRUITING · NA
• PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS — RECRUITING · PHASE2
• First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS) — RECRUITING · PHASE1
• HD-tDCS in Amyotrophic Lateral Sclerosis: A Multicenter Randomized Controlled Trial — RECRUITING · PHASE2
• A Substudy of LY4256984 in Participants With Sporadic Amyotrophic Lateral Sclerosis — RECRUITING · PHASE1
• A Master Protocol (OLMP): A Study of LY4256984 in Participants With Amyotrophic Lateral Sclerosis (ALS) — RECRUITING · PHASE1
• Phase 1/2 Investigation Of Novel Experimental Regimen in Amyotrophic Lateral Sclerosis (PIONEER-ALS): An Open-Label, Uncontrolled, Multicenter Study to Assess the Safety and Tolerability of Two Doses of VTx-002. — RECRUITING · PHASE2
• Personalized Antisense Oligonucleotide Therapy for a Participant With TARDBP ALS — RECRUITING · PHASE1
• Personalized Antisense Oligonucleotide for Participants With CHCHD10 ALS — RECRUITING · PHASE1
• Analysis of Human ALS Tissues and Registry of ALS Patients — RECRUITING
• Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT) — RECRUITING · NA
• Identification of Early Markers for ALS — RECRUITING · NA
• A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS) — RECRUITING · PHASE1
• Neurologic Stem Cell Treatment Study — RECRUITING · NA
• A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS) — RECRUITING · PHASE2
• Healing ALS Registry Observational Study (HAROS) — RECRUITING
• Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS — RECRUITING · PHASE1
• A Study of LTX-002 in Adult Participants With Amyotrophic Lateral Sclerosis — RECRUITING · PHASE1
• A Clinical Trial to Evaluate NB-4746 in Participants With Amyotrophic Lateral Sclerosis. — RECRUITING · PHASE1
• Dazucorilant in Patients With Amyotrophic Lateral Sclerosis — RECRUITING · PHASE2
• Clinical Procedures to Support Research in ALS — RECRUITING
• Dysphagia, QoL and Attitudes Towards PEG in ALS Patients — RECRUITING
• A Study of Ranolazine in ALS — RECRUITING · PHASE2
• Biomarkers in Different Types of Amyotrophic Lateral Sclerosis (ALS) Patients Being Treated With Edaravone — RECRUITING
• Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia — RECRUITING · NA
• BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia — RECRUITING · NA
• Investigating the Impact of Electrical Stimulation on Facial Pain, Jaw Movement and Oral Health in People With Motor Neuron Disease. — RECRUITING · NA
• Genetic Study of Amyotrophic Lateral Sclerosis in Norway — RECRUITING
• Influence of Olfacto-gustatory Sensoriality on the Nutritional Status of Patients With Amyotrophic Lateral Sclerosis — RECRUITING
• Breathing With Amyotrophic Lateral Sclerosis — RECRUITING · NA
• A phase 2, randomized, double-blind, placebo-controlled parallel group study of VHB937 in Amyotrophic Lateral Sclerosis (ALS) over 40 weeks followed by an Open-label Extension (ASTRALS) — RECRUITING · PHASE2

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