Antibody-mediated Rejection Clinical Trials

50 clinical trials for Antibody-mediated Rejection across international registries, including 4 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study to Learn More About the Long-Term Safety and Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR) or Microvascular Inflammation (MVI) (TRANSCEND/TRANSPIRE LTE) — RECRUITING · PHASE3
• A Two Part Dose-escalation Safety and Efficacy Study of CID-103 in Adults With Active and Chronic Active Renal Allograft Antibody Mediated Rejection (ABMR). — RECRUITING · PHASE1
• Biorepository and Registry for Plasma Exchange Patients — RECRUITING
• A Prospective Randomized Trial of ECP in Subclinical AMR — RECRUITING · NA
• Study of SG301 for Renal AMR After Transplantation — NOT_YET_RECRUITING · PHASE2
• Phase 2 Study of ALXN2030 in Patients With Antibody-Mediated Rejection After Kidney Transplantation — ACTIVE_NOT_RECRUITING · PHASE2
• TocIlizumab in Late/Chronic Active Antibody-mediated Rejection in Kidney Transplant Recipients — ACTIVE_NOT_RECRUITING · PHASE3
• CD38 mAb Induction + Azathioprine Maintenance for Chronic Active AMR in Kidney Transplant Recipients — NOT_YET_RECRUITING · NA
• Development and Validation of HistoMX, a Gene-Expression Platform for Molecular Interpretation of Kidney Allograft Biopsies — COMPLETED
• VIRTUUS Children's Study — COMPLETED
• A Study to Evaluate the Safety and Tolerability of Efgartigimod PH20 SC Given by Prefilled Syringe in Kidney Transplant Recipients With Antibody-Mediated Rejection (AMR) — ACTIVE_NOT_RECRUITING · PHASE2
• A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR) — ACTIVE_NOT_RECRUITING · PHASE3
• A Study of Mezagitamab in Adults With Late Antibody-Mediated Rejection (AMR) After a Kidney Transplant — NOT_YET_RECRUITING · PHASE2
• TRAnscriptional Profile of Peripheral Blood Cells in Patient With Chronic Kidney and Lung Rejection: Correlation With Response to Extracorporeal Photo-aphereSiS — ACTIVE_NOT_RECRUITING
• A Global, Multicenter, Randomized, Double-Blinded, Placebo-Controlled, Phase 2 Study to Evaluate the Safety, Tolerability, and Efficacy of Efgartigimod PH20 SC Administered by a Prefilled Syringe in Kidney Transplant Recipients with Antibody Mediated Rejection. — TERMINATED · PHASE2
• Comparison Between Bortezomib and Rituximab Plus Plasmapheresis in AMR — COMPLETED · NA
• Clazakizumab for the Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients — TERMINATED · PHASE3
• Quantitative Parameters of HLA-DQ Antibodies in Lung Transplantation — COMPLETED
• Diagnostic Efficacy of Molecular Diagnostic Method for AMR in ABOiKT — COMPLETED · NA
• Clazakizumab for Chronic and Active Antibody Mediated Rejection Post-Kidney Transplant — COMPLETED · PHASE1
• Transplant Antibody-Mediated Rejection: Guiding Effective Treatments — TERMINATED · PHASE3
• Isatuximab in Lung Transplant Recipients — WITHDRAWN · PHASE1
• Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal Transplant — ACTIVE_NOT_RECRUITING · PHASE1
• Donor-derived Cell-free DNA for Early Diagnosis of Antibody-mediated Rejection — COMPLETED · NA
• Felzartamab in Late Antibody-Mediated Rejection — COMPLETED · PHASE2
• Desensitization in Kidney Allograft Using Daratumumab — COMPLETED · PHASE1
• The Safety and Efficacy of CD38 Monoclonal Antibody Monotherapy for CaAMR in Renal Transplantation — OTHER · NA
• Incidence, Course and Outcome of ABMR in Kidney Transplantation — OTHER
• Subclass of Donor-specific Antibody as a Risk Factor of Antibody Mediated Rejection in Renal Transplantation — COMPLETED
• Belatacept Pilot Study in Lung Transplantation Immunosuppression in Lung Transplantation — COMPLETED · PHASE2
• Combined Apheresis for ABO-incompatible Transplantation - a Pilot Study — TERMINATED · NA
• Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR) in Adult Renal Transplant Recipients — TERMINATED · PHASE3
• MuLtimodality EvaluatiOn of aNtibody mEdiated Damage in Heart Transplantation (LEONE-HT) — ACTIVE_NOT_RECRUITING
• DSA Risk Factors in MMF-based Immunosuppressed Post-transplanted Patients — OTHER
• DSA Intragraft in Lung Transplantation: Diagnostic and Prognostic Value in Antibody Mediated Rejection — OTHER · NA
• HPA Antibodies and the Distribution of Antigen and Antibodies — COMPLETED · NA
• Effects of A Standardized Treatment Approach on Kidney Transplant Recipients With Antibody-Mediated Rejection — COMPLETED
• The De-novo Use of Eculizumab in Presensitized Patients Receiving Cardiac Transplantation — COMPLETED · PHASE3
• A Pilot Trial of Clazakizumab in Late ABMR — COMPLETED · PHASE2
• Treatment of Chronic Active Antibody Mediated Rejection After Kidney Transplantation by Double-Filtration PlasmaPheresis or Plasma Exchange — OTHER · NA
• Lung Transplant Plasmapheresis/Belatacept/Carfilzomib for Antibody Mediated Rejection and Desensitization — WITHDRAWN · PHASE2
• Antibodies and Liver Retransplantation — OTHER
• Belatacept in Kidney Transplantation of Moderately Sensitized Patients — WITHDRAWN · PHASE4
• Cyclophosphamide Therapy for Refractory Antibody-Mediated Rejection (AMR) in Kidney Transplants — TERMINATED · PHASE2
• Analysis of Biopsies With Antibody Mediated Rejection According to the Therapy Response — OTHER
• Safety & Efficacy of Eculizumab to Prevent AMR in Living Donor Kidney Transplant Recipients Requiring Desensitization — TERMINATED · PHASE2
• Efficacy and Safety of Eculizumab for Treatment of Antibody-mediated Rejection Following Renal Transplantation — TERMINATED · PHASE2
• Endothelial Injury and Development of Coronary Intimal Thickening After Heart Transplantation — TERMINATED · PHASE1
• Bortezomib in Late Antibody-mediated Kidney Transplant Rejection — COMPLETED · PHASE2
• Elimination of Cardiac and Inflammatory Biomarkers and Adipokines by Therapeutic Plasma Exchange — COMPLETED

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