Autosomal Dominant Polycystic Kidney Disease Clinical Trials

100 clinical trials for Autosomal Dominant Polycystic Kidney Disease across international registries, including 19 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Managing Depressive Symptoms in ADPKD — RECRUITING · NA
• ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD) — RECRUITING · PHASE2
• Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease — RECRUITING · PHASE1
• Phase 1 Study to Evaluate the Safety and Tolerability of Intravenously Administered PYC-003 — RECRUITING · PHASE1
• A Phase 2a, Open-label, Single-arm Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of VX-407 in Subjects with Autosomal Dominant Polycystic Kidney Disease Who Have a Subset of PKD1 Gene Variants — RECRUITING · PHASE2
• STOP-PKD: SGLT2-inhibition to improve Prognosis in Polycystic Kidney Disease — RECRUITING · PHASE3
• RADIOLOGICAL AND CLINICAL EVALUATION OF RENAL EMBOLIZATION USING EVOH IN DIALYSIS PATIENTS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE: A PROSPECTIVE LONGITUDINAL OBSERVATIONAL STUDY — RECRUITING
• Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD) — RECRUITING · PHASE3
• Metabolic Impacts of Ren-Nu: A Dietary Program for Polycystic Kidney Disease — RECRUITING · NA
• Autosomal Dominant Polycystic Kidney Disease Somatic Mutation Biorepository — RECRUITING
• Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) — RECRUITING
• NOX4 and Related Biomarkers in ADPKD — RECRUITING
• Short-term Effects of an SGLT2 Inhibitor on Divalent Ions in Autosomal Dominant Polycystic Kidney Disease — RECRUITING · PHASE2
• A RANDOMISED, DOUBLE BLIND, PLACEBO-CONTROLLED, SINGLE ASCENDING DOSE, PHASE 1A/1B MULTI-CENTRE STUDY IN HEALTHY PARTICIPANTS AND PARTICIPANTS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF GSK4771261 — RECRUITING · PHASE1
• National Registry of Rare Kidney Diseases — RECRUITING
• Atorvastatin and Alkali Therapy in Patients With Autosomal Dominant Polycystic Kidney Disease — RECRUITING · PHASE2
• A PHASE 3 STUDY OF THE EFFICACY AND SAFETY OF LIXIVAPTAN IN PARTICIPANTS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE CONSISTING OF A 1-YEAR DOUBLE-BLIND, PLACEBO-CONTROLLED, RANDOMIZED PHASE AND A 1-YEAR OPEN LABEL PHASE: THE ACTION STUDY — RECRUITING · PHASE3
• MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TWO STAGE STUDY TO CHARACTERIZE THE EFFICACY, SAFETY, TOLERABILITY AND PHARMACOKINETICS OF GZ/SAR402671 IN PATIENTS AT RISK OF RAPIDLY PROGRESSIVE AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD). — RECRUITING
• A PILOT STUDY OF CYSTIC VOLUME REDUCTION BY FOAM SCLEROTHERAPY IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE — RECRUITING
• Effects of Sirolimus on disease progression in patients with Autosomal Dominant Polycystic Kidney Disease and severe renal insufficiency — TERMINATED · PHASE2
• Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW) — ACTIVE_NOT_RECRUITING · PHASE2
• A First-in-Human Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of MR-L45 in Healthy Adults — TERMINATED · PHASE1
• Polycystic Kidney Disease 1 (PKD1) Gene Variant Groups in Autosomal Dominant Polycystic Kidney Disease — ACTIVE_NOT_RECRUITING
• Dietary Modulation of Urinary MCP-1 in ADPKD — NOT_YET_RECRUITING · NA
• A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of ABBV-CLS-628 in Adult Subjects with Autosomal Dominant Polycystic Kidney Disease (ADPKD) — TERMINATED · PHASE2
• A study to investigate the safety, tolerability, pharmacokinetics, immunogenicity and pharmacodynamics of a single subcutaneous dose of GSK4771261 in healthy participants aged 25 to 55 years of age inclusive — COMPLETED · PHASE1
• Renal Denervation in ADPKD- RDN-ADPKD Study — ACTIVE_NOT_RECRUITING · NA
• Observational Study in Patients With Autosomal Dominant Polycystic Kidney Disease — COMPLETED
• A Study to Evaluate Homocysteine Metabolism and Endothelial Function in ADPKD — ACTIVE_NOT_RECRUITING
• Effects of VX-407 on the Pharmacokinetics of Oral Contraceptives in Healthy Participants — COMPLETED · PHASE1
• A Phase 1 Study Evaluating Safety, Tolerability, and Pharmacokinetics of VX-407 in Healthy Participants — COMPLETED · PHASE1
• A Possible Founding PKD2 Mutation Associated With Variable Phenotypes of ADPKD in Bergamo Province — COMPLETED
• Metformin versus Tolvaptan in adults with Autosomal Dominant Polycystic Kidney Disease (ADPKD): a phase 3a, independent, multi- centre, 2 parallel arms randomized controlled trial — TERMINATED · PHASE3
• Di-PKD: A Pilot Trial of Dietary Intervention in Patients With Autosomal Dominant Polycystic Kidney Disease — NOT_YET_RECRUITING · NA
• Probenecid (PB) to Treat Hereditary Nephrogenic Diabetes Insipidus (NDI), ADPKD Treated With Tolvaptan, and Severely Polyuric Patients With Previous Lithium Administration — COMPLETED · PHASE2
• Robotic vs Open Nephrectomy for ADPKD — ACTIVE_NOT_RECRUITING
• Intrarenal Microvasculature in ADPKD — ACTIVE_NOT_RECRUITING
• Canadian Medical Assessment of JINARC™ Outcomes Registry — COMPLETED
• Role of ROS and cAMP-PKA Biomarkers in ADPKD — ACTIVE_NOT_RECRUITING
• Study of Empagliflozin in Patients with Autosomal Dominant Polycystic Kidney Disease — TERMINATED · PHASE4
• Drug-Drug Interaction of JMKX003142 With Amiodarone and Febuxostat in Healthy Subjects — NOT_YET_RECRUITING · PHASE1
• Simulated and Synthetic Health Data: Improving Clinical Research on Rare Diseases. A Real-World Data Simulation of Autosomal Dominant Polycystic Kidney Disease (ADPKD) Trials. A Retrospective, Observational Study — ACTIVE_NOT_RECRUITING
• Pravastatin and Alkali Therapy in Patients With Autosomal Dominant Polycystic Kidney Disease — COMPLETED · PHASE2
• A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of VX-407 in Healthy Participants — COMPLETED · PHASE1
• A Study of RGLS8429 in Patients With Autosomal Dominant Polycystic Kidney Disease — COMPLETED · PHASE1
• Study of Tamibarotene in Patients With ADPKD — ACTIVE_NOT_RECRUITING · PHASE2
• A PHASE 2, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE SAFETY AND EFFICACY OF ABBV-CLS-628 IN ADULT SUBJECTS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD) — NOT_YET_RECRUITING · PHASE2
• Artificial Intelligence-based Image Processing Methods to Advance the Characterization of Polycystic Kidney Disease — ACTIVE_NOT_RECRUITING
• A Study to Evaluate the Effects of GLPG2737 in Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD) — TERMINATED · PHASE2
• Treatment of vascular stiffness in patients with autosomal dominant polycystic kidney disease — OTHER · PHASE4

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