Bipolar I Disorder Clinical Trials

134 clinical trials for Bipolar I Disorder across international registries, including 20 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects — RECRUITING · PHASE3
• Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder — RECRUITING · PHASE3
• A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder — RECRUITING · PHASE2
• Safety and Feasibility of DBS for Bipolar Depression — RECRUITING · NA
• An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania — RECRUITING · PHASE2
• A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolar I Disorder — RECRUITING · PHASE1
• Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE. — RECRUITING · PHASE2
• A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder. — RECRUITING · PHASE3
• Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder — RECRUITING · PHASE2
• Open Label Extension Study of NCT06221852 — RECRUITING · NA
• An Open-label Study of Azetukalner in Bipolar I or II Depression (X-CEED-OLE) — RECRUITING · PHASE3
• A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression) — RECRUITING · PHASE3
• SYNCED - SYNChronized Eating in Bipolar Depression Study — RECRUITING · NA
• Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine Depot) in Subjects Eligible for Treatment With Oral Cariprazine — RECRUITING · PHASE1
• Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder — RECRUITING · PHASE4
• LHC-CIDI-5 in Hong Kong — RECRUITING
• Children's Bipolar Network Treatment Trial I — RECRUITING
• Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder — RECRUITING · NA
• Safety and Tolerability of Open-Labeled Iloperidone in Adolescents — RECRUITING · PHASE4
• NMDA Receptor Modulation for the Treatment of Bipolar I Disorder — RECRUITING · PHASE2
• Multicenter, Randomized, Parallel-group, Double-blind, Placebo-controlled Phase III Study of the Efficacy and Safety of Quetiapine Fumarate and Lithium as Monotherapy for up to 104 weeks Maintenance Treatment of Bipolar I Disorder in Adult Patients — TERMINATED · PHASE3
• Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders — COMPLETED · PHASE2
• Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia and Bipolar Disorder (SERENITY III) — COMPLETED · PHASE3
• Assessment of Acute Psychomotor Agitation Measures Associated With Schizophrenia and Bipolar Disorder — COMPLETED · PHASE2
• A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy and Safety of Lumateperone in the Acute Treatment of Patients with Manic Episodes or Manic Episodes with Mixed Features Associated with Bipolar I Disorder (Bipolar Mania) — OTHER · PHASE3
• A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy and Safety of Lumateperone in the Acute Treatment of Patients with Manic Episodes or Manic Episodes with Mixed Features Associated with Bipolar I Disorder (Bipolar Mania) — OTHER · PHASE3
• A Study of Elpipodect (MK-8189) in Participants With Bipolar I Disorder (MK-8189-020) — COMPLETED · PHASE1
• Low Field Magnetic Stimulation: Imaging Biomarkers in Geriatric Bipolar Depression — ACTIVE_NOT_RECRUITING · NA
• A Study of Spoken Language in Mania — COMPLETED · NA
• Early Psychosis Intervention - Spreading Evidence-based Treatment — COMPLETED · NA
• Maintenance Ketamine Infusions for Treatment-Resistant Bipolar Depression — COMPLETED · PHASE2
• Ketamine for Treatment-Resistant Bipolar Disorder — COMPLETED · PHASE2
• Observational Study of Oral Cariprazine Capsules to Assess Change in Disease Activity in Adult Participants With Bipolar I Disorder — COMPLETED
• Braining- Aerobic Physical Activity as Add on Treatment in Bipolar Depression — SUSPENDED · NA
• Study of Oral ABBV-932 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Bipolar I or II Disorder — COMPLETED · PHASE2
• Sequential Multiple Assignment Randomized Trial for Bipolar Depression — ACTIVE_NOT_RECRUITING · PHASE4
• Open-Label, Flexible-dose Study to Evaluate the Long-Term Safety and Tolerability of Cariprazine in the Treatment of Pediatric Participants With Schizophrenia, Bipolar I Disorder, or Autism Spectrum Disorder — COMPLETED · PHASE3
• Pharmacokinetic Study of VHX-896 and Iloperidone Tablets Under Steady-State Conditions — COMPLETED · PHASE1
• ERG Components in Schizophrenia and Bipolar Disorder Type I — ACTIVE_NOT_RECRUITING
• A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Bipolar Disorder — WITHDRAWN
• Mood Stabilizer (MS)+ Antidepressant vs MS + Placebo in Maintenance of Bipolar Disorder. — TERMINATED · PHASE3
• CBT for Problematic Impulsive Behaviours in Bipolar Disorder: A Case Series / CBT-PIB — SUSPENDED · NA
• Effects of Intranasal Insulin on Neuroimaging Markers and Cognition in Patients With Psychotic Disorders — COMPLETED · PHASE2
• A Double-Blind, Oral, Placebo-Controlled, Multiple-Dose, Parallel, Randomized Study to Evaluate Efficacy and Safety of Endoxifen in Bipolar I Disorder Patients — OTHER · PHASE3
• Efficacy of Convulsive Therapies for Bipolar Depression — COMPLETED · NA
• Assessing the Role of Cariprazine in Improving Cognition in Euthymic Bipolar Patients — TERMINATED · PHASE3
• Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831 — COMPLETED · PHASE3
• Evaluate Efficacy and Safety of Endoxifen in Bipolar I Disorder Patients — COMPLETED · PHASE3
• Study to Assess Accuracy of Rapid Mood Screener in Adult Participants With Unipolar Major Depressive Disorder or Bipolar 1 Disorder in Real World Setting — COMPLETED
• iTBS in Bipolar I Depression — COMPLETED · NA

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