Chronic Graft Versus Host Disease Clinical Trials

123 clinical trials for Chronic Graft Versus Host Disease across international registries, including 25 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Dental Cleaning to Prevent Chronic Graft-Versus-Host Disease — RECRUITING · NA
• Axatilimab for Sclerotic Chronic Graft-versus-Host Disease — RECRUITING · PHASE2
• A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease — RECRUITING · PHASE3
• Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy — RECRUITING · PHASE2
• A Long-term Extension Study of PCI-32765 (Ibrutinib) — RECRUITING · PHASE3
• Tissue Immune Landscape of Graft Versus Host Disease After Allogeneic Stem Cell Transplantation (TIL-GVHD) — RECRUITING · NA
• Axatilimab in Combination With Extracorporeal Photopheresis (ECP) in Chronic Graft-versus-Host Disease — RECRUITING · PHASE2
• A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD) — RECRUITING · PHASE2
• BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP) — RECRUITING · PHASE2
• An open-label, Phase 1/2, multicenter study of belumosudil in children aged 1 to <18 years requiring systemic treatment for active moderate-to-severe chronic graft versus host disease (cGVHD). — RECRUITING · PHASE2
• A Study of Belumosudil in Children With Chronic Graft Versus Host Disease (schoolROCK) — RECRUITING · PHASE2
• Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease — RECRUITING · PHASE2
• A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256) — RECRUITING · PHASE2
• A Prospective Study of Madecassoside Tablets in Sclerotic Chronic Graft-versus-Host Disease After Allo-HSCT — RECRUITING · PHASE2
• Belumosudil and Rituximab for Primary Treatment of Chronic Graft-Versus-Host-Disease — RECRUITING · PHASE2
• A multiCenter phase I study of aUtologous CD19 CAR T cElls for therapy refractory chronic GvHD (CURE-cGvHD) — RECRUITING · PHASE1
• Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial — RECRUITING · NA
• Evaluation of Belumosudil Whole Tablets vs. Crushed Tablets Pharmacokinetics in Patients Suffering From Chronic GvHD — RECRUITING
• Ruxolitinib Plus Fostamatinib for Steroid Refractory cGvHD — RECRUITING · PHASE1
• A Study to Evaluate Adrixetinib (Q702) in Adults With Active Chronic Graft-Versus-Host Disease — RECRUITING · PHASE1
• A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD) — RECRUITING · PHASE2
• A Phase 3, Randomized, Open-Label Study of Axatilimab Versus Best Available Therapy in Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy — RECRUITING · PHASE3
• Gecacitinib for cGVHD: Safety and Efficacy in Patients After ≥2 Lines of Prior Therapy — RECRUITING · PHASE1
• A Clinical Trial of TQ05105 Tablets in the Treatment of Chronic Graft-versus-host Disease — RECRUITING · PHASE2
• Therapeutic Effects of Hydrogen on Steroid-refractory/or Steroid-dependent cGVHD — RECRUITING · PHASE2
• A Ph1b/2 Study of Axatilimab Monotherapy in Chinese Participants With Recurrent or Refractory cGVHD — ACTIVE_NOT_RECRUITING · PHASE1
• Mindfulness Intervention to Reduce Patient Reported Symptoms in Patients With Chronic Graft-Versus-Host Disease — NOT_YET_RECRUITING · NA
• Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation — ACTIVE_NOT_RECRUITING · PHASE1
• Study to Compare the Plasma Concentration of Belumosudil Given as an Oral Suspension and as a Tablet to Healthy Adult Male Participants — NOT_YET_RECRUITING · PHASE1
• Psychosocial Mobile App for Chronic Graft-Versus-Host Disease — ACTIVE_NOT_RECRUITING · NA
• INCA34176-254: A Phase 2, Open-Label, Randomized, Multicenter Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease — TERMINATED · PHASE2
• Predicting the Quality of Response to Specific Treatments in Patients With cGVHD, PQRST Study — ACTIVE_NOT_RECRUITING
• Leflunomide in Treating Patients With Steroid Dependent Chronic Graft Versus Host Disease — ACTIVE_NOT_RECRUITING · PHASE1
• AGAVE-201, A Phase 2, Open-label, Randomized, Multicenter Study to Evaluate the Efficacy, Safety and Tolerability of Axatilimab at 3 Different Doses in Patients with Recurrent or Refractory Active Chronic Graft Versus Host Disease who have Received at least 2 Lines of Systemic Therapy. — TERMINATED · PHASE2
• A Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Itacitinib — TERMINATED · PHASE2
• A Phase 2, Randomized, Open-Label Study Of Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256) — TERMINATED · PHASE2
• Abatacept to Treat Steroid Refractory Chronic Graft Versus Host Disease (cGVHD) — COMPLETED · PHASE1
• A Clinical Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Belumosudil in Chinese Adolescents With cGVHD Who Have Had an Inadequate Response to Glucocorticoids or Other Systemic Therapies — COMPLETED · PHASE4
• A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Axatilimab (INCA034176) and Corticosteroids as Initial Treatment for Chronic Graft-Versus Host Disease (AXemplify 357) — TERMINATED · PHASE3
• Ibrutinib for the Prevention of Chronic Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant — TERMINATED · PHASE2
• A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease — ACTIVE_NOT_RECRUITING · PHASE2
• A Study to Investigate Safety of Belumosudil in Participants Aged 12 Years and Above, With Chronic Graft-versus-host Disease (cGVHD) — NOT_YET_RECRUITING · PHASE4
• Improving Outcomes Assessment in Chronic GVHD — ACTIVE_NOT_RECRUITING
• Establishment of Biomarker Panel For Forecasting Chronic Graft-Versus-Host Disease (cGVHD) After Allo-HSCT — NOT_YET_RECRUITING · NA
• Tele-Palliative Care Intervention for Patients With Chronic Graft-Versus-Host Disease — ACTIVE_NOT_RECRUITING · NA
• Digital Health Intervention to Promote Quality of Life in Adults With Chronic Graft Versus Host Disease — ACTIVE_NOT_RECRUITING · NA
• A Study to Evaluate Axatilimab Versus Best Available Therapy in Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy — ACTIVE_NOT_RECRUITING · PHASE3
• Dendritic Cells in Patients With Acute or Chronic Skin Graft Versus Host Disease — ACTIVE_NOT_RECRUITING
• Upfront Ruxolitinib for Chronic Graft-vs-host Disease — TERMINATED · PHASE1
• Study of Q702 in Subjects with Relapsed or Refractory Chronic Graft-versus-Host Disease (cGVHD) — TERMINATED · PHASE1

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