Chronic Granulomatous Disease Clinical Trials

56 clinical trials for Chronic Granulomatous Disease across international registries, including 11 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Part B- G1X-CGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease — RECRUITING · PHASE1
• Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease — RECRUITING · PHASE1
• Evaluation of Patients With Immune Function Abnormalities — RECRUITING
• NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD) — RECRUITING · PHASE1
• Lentiviral Gene Therapy for CGD — RECRUITING · NA
• Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD) — RECRUITING · PHASE2
• Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists — RECRUITING · PHASE1
• A Study of the Safety and Efficacy of Prime Editing (PM359) in Participants With p47phox Autosomal Recessive Chronic Granulomatous Disease (CGD ) — RECRUITING · PHASE1
• Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease — RECRUITING
• pCCLCHIM-p47 (Lentiviral Vector Transduced CD34 Plus Cells) in Patients With p47 Autosomal Recessive Chronic Granulomatous Disease (AR-CGD) — RECRUITING · PHASE1
• Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases — RECRUITING · PHASE1
• Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer — COMPLETED
• Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide — ACTIVE_NOT_RECRUITING · PHASE1
• Analysis of Patients Treated for Chronic Granulomatous Disease Since January 1, 1995 — COMPLETED
• Early Check: Expanded Screening in Newborns — ACTIVE_NOT_RECRUITING
• Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies — ACTIVE_NOT_RECRUITING · NA
• Genetic Disorders of Mucociliary Clearance in Nontuberculous Mycobacterial Lung Disease — COMPLETED
• Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease With Inflammatory Complications — COMPLETED · PHASE1
• Immune Disorder HSCT Protocol — ACTIVE_NOT_RECRUITING · PHASE2
• Elemental Diet for Treatment of Inflammatory Bowel Disease in Patients With Chronic Granulomatous Disease — COMPLETED · PHASE2
• Gene Therapy for Chronic Granulomatous Disease in Korea — WITHDRAWN · PHASE1
• Study to Assess the Use of JSP191 in Matched Unrelated Donor Transplantation for Chronic Granulomatous Disease (CGD) — ACTIVE_NOT_RECRUITING · PHASE1
• Baby Detect : Genomic Newborn Screening — COMPLETED
• Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer — TERMINATED · PHASE2
• Skin Immunity Sample Collection Involving Blisters and Biopsies — WITHDRAWN · PHASE1
• Vitamin D3 For CGD Patients With BCGosis/Itis — COMPLETED · PHASE2
• Whole Blood Biospecimen Collection for Subjects With Chronic Granulomatous Disease (CGD) — TERMINATED
• Neutrophil Oxidative Burst in Early and Late Onset Pediatric Inflammatory Bowel Disease — OTHER
• Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation — COMPLETED · PHASE1
• Natural History of Intestinal Inflammation in People With Primary Immune Dysregulations — WITHDRAWN
• Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204) — COMPLETED · PHASE2
• Non-Invasive Assessment of Atherosclerosis in Patients With CGD and Other Disorders of the Immune System — COMPLETED
• Role of Interferon-gamma 1-b (IFN-γ) on Cells of the Innate Immune System: Functional, Biochemical and Gene Expression Studies in Patients With Chronic Granulomatous Disease — COMPLETED
• Pharmacokinetics of Posaconazole in Children With Chronic Granulomatous Disease (CGD) — COMPLETED · PHASE2
• Haploidentical Transplant for People With Chronic Granulomatous Disease Using Post Transplant Cyclophosphamide — TERMINATED · PHASE1
• IL-1 Receptor Inhibitor for Granulomatous Complications in Patients With Chronic Granulomatous Disease — COMPLETED · PHASE1
• Bone Marrow Transplant With Abatacept for Non-Malignant Diseases — COMPLETED · PHASE1
• Pioglitazone Therapy for Chronic Granulomatous Disease — TERMINATED · PHASE1
• Plerixafor/G-CSF as Additional Agents for Conditioning Before HSCT in CGD Patients — OTHER · PHASE2
• Effect of IFN-γ on Innate Immune Cells — COMPLETED · PHASE1
• Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous Disease — COMPLETED · PHASE2
• Gene Therapy for Chronic Granulomatous Disease — TERMINATED · PHASE1
• Generation of Powerful Biological Tools for Understanding the Pathophysiology of Chronic Granulomatous Disease. — TERMINATED · NA
• Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation — TERMINATED · NA
• Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up — COMPLETED · PHASE1
• Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood Cells — TERMINATED · PHASE2
• Infliximab to Treat Crohn'S-like Inflammatory Bowel Disease in Chronic Granulomatous Disease — TERMINATED · PHASE1
• Targeted Busulfan, Fludarabine Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Chronic Granulomatous Disease(CGD) — OTHER · PHASE1
• Gene Therapy for X-linked Chronic Granulomatous Disease (CGD) in Children — COMPLETED · PHASE1
• Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies — TERMINATED · NA

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