Chronic Rhinosinusitis With Nasal Polyps Clinical Trials

107 clinical trials for Chronic Rhinosinusitis With Nasal Polyps across international registries, including 26 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study to Investigate NPS and Symptoms in Chinese Adult Participants With CRSwNP Initiating Treatment With Tezepelumab — RECRUITING · PHASE3
• A Study to Investigate the Clinical Outcome and Quality of Life in Chinese Post-operative CRSwNP Patients — RECRUITING
• ReAl-woRld Evaluation of tEzepelumab for Chronic rhinoSinusitis With Nasal Polyps in Russia — RECRUITING
• A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP) — RECRUITING · PHASE3
• A double-blinded extension study to evaluate the long-term safety and tolerability of itepekimab in adult participants with inadequately controlled chronic rhinosinusitis with nasal polyps (CRSwNP) who participated in either EFC18418 or EFC18419 clinical studies — RECRUITING · PHASE3
• Implementation of a Joint Pulmonologist and ENT Consultation in the Care Pathway of Patients Suffering From Asthma and Chronic Rhinosinusitis With Nasal Polyposis: Effectiveness Compared With Consultations by Specialty (CON-PO Study). — RECRUITING · NA
• Prospective, Non-interventional Single-arm Study With Tezepelumab to Investigate the Change in Clinical and Patient-reported Outcomes in Patients With CRSwNP in Real-world (PETRICHOR) — RECRUITING
• A Study of BBT002 in Healthy Volunteers (HVs) and in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) With or Without Comorbid Asthma — RECRUITING · PHASE1
• Long-term Safety and Efficacy Evaluation of Lunsekimig in Adult Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Who Completed a Previous Lunsekimig CRSwNP Clinical Study — RECRUITING · PHASE2
• 3D Printing to Improve Nasal Irrigation Outcome — RECRUITING · NA
• Polysomnographic Findings in Nasal Polyposis — RECRUITING · NA
• Upper Airway Inflammation and Olfaction: Mechanisms of Loss and Recovery — RECRUITING · NA
• Dupilumab Treatment Effects in an Ethnically Diverse Population With Chronic Rhinosinusitis With Nasal Polyposis — RECRUITING
• Real-Time Diagnosis of Eosinophilic Nasal Polyps Using High-Sensitivity Spectroscopy — RECRUITING · NA
• Clinical Trial of TQC2731 Injection in Patients With Chronic Sinusitis and Nasal Polyps — RECRUITING · PHASE3
• Efficacy and Safety of SHR-1905 Injection in Subjects With Chronic Rhinosinusitis With Nasal Polyps — RECRUITING · PHASE3
• Tapering of Biologics in Chronic Rhinosinusitis With Nasal Polyps — RECRUITING · PHASE4
• Sinonasal Microbiome Transplant as a Therapy for Chronic Rhinosinusitis (CRS). — RECRUITING · PHASE2
• Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal Polyps — RECRUITING · NA
• Effect of Dupilumab on Nasal Epithelial Barrier Function in Patients With CRSwNP — RECRUITING
• Identifying Predictors Of Response To Mepolizumab In CRSwNP — RECRUITING · PHASE4
• Olfactory Outcomes of Dupilumab Treatment for Nasal Polyposis — RECRUITING · PHASE4
• Real-life Evaluation of the Efficacy of Biologicals in Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP) — RECRUITING
• Real Life Study of Biologicals in Patients With Severe CRSwNP — RECRUITING
• Basal Instincts: Towards Better Understanding of Basal Cell Function in Chronic Rhinosinusitis With Nasal Polyps — RECRUITING
• Biomarkers of Response to Mepolizumab Treatment in Patients With Nasal Polyps With or Without Bronchial Asthma — RECRUITING
• A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Adult Japanese Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps — WITHDRAWN · PHASE3
• An Extension Study to Investigate the Long-term Safety and Tolerability of Itepekimab in Adult Participants With Inadequately Controlled Chronic Rhinosinusitis With Nasal Polyps — ACTIVE_NOT_RECRUITING · PHASE3
• A Study to Evaluate the Efficacy and Safety of AK139 in Participants With Chronic Rhinosinusitis With Nasal Polyps — NOT_YET_RECRUITING · PHASE2
• A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab — ACTIVE_NOT_RECRUITING · PHASE3
• Mechanisms of Smell Improvement With Dupilumab. — COMPLETED · PHASE4
• A randomized, double blind, placebo controlled, parallel group, 52­week Phase 3 trial to investigate the efficacy, safety, and tolerability of itepekimab in adult participants with inadequately-controlled chronic rhinosinusitis with nasal polyps — TERMINATED · PHASE3
• A randomized, double blind, placebo controlled, parallel group, 52­week Phase 3 trial to investigate the efficacy, safety, and tolerability of itepekimab in adult participants with inadequately-controlled chronic rhinosinusitis with nasal polyps — TERMINATED · PHASE3
• Efficacy and Safety of SHR-1905 Injection in Patients With Chronic Rhinosinusitis With Nasal Polyps — COMPLETED · PHASE2
• A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Lebrikizumab/LY3650150 in Participants with Chronic Rhinosinusitis with Nasal Polyps on Background Intranasal Corticosteroids — TERMINATED · PHASE3
• The Role of IL5 in Epithelial Cell Integrity — COMPLETED · PHASE1
• A single-arm extension study to investigate the long-term safety, tolerability, and efficacy of lunsekimig in adult participants with inadequately controlled chronic rhinosinusitis with nasal polyps (CRSwNP) who completed a previous lunsekimig CRSwNP clinical study — TERMINATED · PHASE2
• Thermosensitive Gel Nasal Spray With Stem Cell Exosomes, Mupirocin, and DNase I for Chronic Sinusitis — NOT_YET_RECRUITING · PHASE1
• Tezepelumab (Tezspire) Regulatory Postmarketing Surveillance in Korea — NOT_YET_RECRUITING
• A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps — ACTIVE_NOT_RECRUITING · PHASE3
• Preoperative Stapokibart for Endoscopic Sinus Surgery in Chronic Rhinosinusitis With Nasal Polyps — NOT_YET_RECRUITING · NA
• Regulatory Post-Marketing Surveillance of Xolair® for Chronic Rhinosinusitis With Nasal Polyps — COMPLETED
• A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps — ACTIVE_NOT_RECRUITING · PHASE3
• Dual REmission in Moderate-to-SEvere asthMa and Nasal Polyps — COMPLETED
• BIOlogics in Severe Nasal POlyposis SurvEy — ACTIVE_NOT_RECRUITING
• A Proof-of-concept Study of Lunsekimig Compared With Placebo in Adults With Chronic Rhinosinusitis With Nasal Polyps — COMPLETED · PHASE2
• Mepolizumab Effectiveness in Patients With Chronic Rhinosinusitis, Nasal Polyps and Comorbid Severe Eosinophilic Asthma — ACTIVE_NOT_RECRUITING
• Phenotyping of Type 2 Inflammation Profile by Rheology of Nasal Secretions and Tissue Quantification of Eosinophilic Polymorphonuclear Cells in the Middle Turbinate — NOT_YET_RECRUITING · NA
• Aggravated Airway Inflammation: Research on Biological Treatment (Mepolizumab) — COMPLETED · PHASE4
• Direct comparison of Tezepelumab and Dupilumab in CRSwNP in a real world setting — NOT_YET_RECRUITING · PHASE4

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