Colorectal Cancer Metastatic Clinical Trials

212 clinical trials for Colorectal Cancer Metastatic across international registries, including 49 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• BAL/BOT/agenT-797 in pMMR CRC With Liver Metastases — RECRUITING · PHASE2
• Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases — RECRUITING
• A Phase II Clinical Study of Multimodal Ablation Combined With Systemic Drug Therapy for Advanced Solid Tumors. — RECRUITING · PHASE2
• Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection — RECRUITING
• Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis — RECRUITING · PHASE1
• China Metastatic Liver Cancer Clinical Registry Cohort Database — RECRUITING
• Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases — RECRUITING · PHASE2
• Technical Feasibility of Modified Early Post-Operative Intraperitoneal Chemotherapy (mEPIC) — RECRUITING · PHASE2
• The Efficacy and Safety of IBI351, Cetuximab β Combined With FOLFIRI as First-line /IBI351, Cetuximab β as Second-line in the Treatment of KRAS G12C-mutated Metastatic Colorectal Cancer — RECRUITING · PHASE2
• In Vivo Lung Perfusion (IVLP) for Colorectal Cancer Metastatic to Lung — RECRUITING · PHASE1
• TL938 and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer — RECRUITING · PHASE2
• Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS) — RECRUITING · PHASE2
• INFINITIVE: ImmuNotherapy For PatIeNts wIth colorecTal LIVer MEtastases — RECRUITING · PHASE1
• Dual-Target CAR-NK Cells for Biomarker-Selected Advanced Colorectal Cancer — RECRUITING · PHASE1
• Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy — RECRUITING · PHASE2
• A Study of CNA3103 (LGR5-targeted, Autologous CAR-T Cells) Administered to Subjects With Metastatic Colorectal Cancer — RECRUITING · PHASE1
• COLONYVAQ™, a Quantum-Classical Guided Personalized Neoantigen Vaccine for MSS Stage III Colorectal Cancer — RECRUITING · PHASE1
• Clinical Study of Second-line Treatment in Advanced Colorectal Cancer With Chemotherapy With Bevacizumab or Cetuximab — RECRUITING · PHASE2
• ValproIc Acid to Potentiate Anti-EGFR Treatment Efficacy and Prevent/Revert Resistance in Colorectal Cancer — RECRUITING · PHASE2
• STREAM-2: Second-line Treatment With REgorafenib in Advanced RAS-Mutant Colorectal Cancer — RECRUITING · PHASE2
• A Study of ABT-301 Plus Tislelizumab With Bevacizumab in pMMR/Non-MSI-H Locally Advanced or mCRC — RECRUITING · PHASE1
• Prospective National Cohort Evaluating Predictive Biomarkers of Resistance to Immunotherapy in Patients With MSI/dMMR Metastatic Colorectal Cancer (CORESIM) — RECRUITING
• Efficacy and Safety of Tunlametinib Plus Vemurafenib in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer — RECRUITING · PHASE3
• Oral Chemotherapy, Targeted Therapy and Immunotherapy With/Without Radiotherapy as 3rd- or Later-line Therapy for Advanced MSS/pMMR Colorectal Cancer — RECRUITING · PHASE2
• Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test — RECRUITING
• Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer — RECRUITING
• Medical Cannabis in Patients With Advanced Pancreatic and Colorectal Cancer — RECRUITING · PHASE2
• A Dose-Expansion Trial of Intravenous HNF4α srRNA for Unresectable or Metastatic Colorectal Cancer — RECRUITING · PHASE1
• Clinical Study of Irinotecan Liposome (II)-Based Combination Treatment for Irinotecan-resistant Colorectal Cancer. — RECRUITING · PHASE2
• ctDNA-Guided Cetuximab or Bevacizumab Plus Trifluridine/Tipiracil in RAS/BRAF Wild-Type mCRC — RECRUITING · PHASE1
• ctDNA Monitoring in Patients With HCC and mCRC — RECRUITING · NA
• FOLFOX Via HAI Plus Intravenous Irinotecan With or Without Bevacizumab Versus Systemic FOLFOXIRI With or Without Bevacizumab in Initially Unresectable RAS-mutated CRLM Patients — RECRUITING · PHASE2
• Trifluridine/Tipiracil Plus Regorafenib vs Trifluridine/Tipiracil Plus Bevacizumab for Refractory Metastatic Colorectal Cancer — RECRUITING · PHASE3
• DEBIRI Plus Chemotherapy vs. Chemotherapy Alone in Colorectal Cancer Liver Metastases — RECRUITING · PHASE3
• Irinotecan Liposomes Combined with Cetuximab + Vermofenib in First-line Failure of Advanced Colorectal Cancer — RECRUITING · PHASE2
• Cryoablation Combined with Sintilimab Plus Regorafenib in Previously Treated Colorectal Cancer Liver Metastasis — RECRUITING · PHASE2
• Regorafenib and Sintilimab in Combination with Electroacupuncture in MSS CRC — RECRUITING · NA
• Efficacy and Safety of Chemotherapy With XELOX (Oxaliplatin + Capecitabine) and Bevacizumab in Combination With Adebrelimab in First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer — RECRUITING · PHASE2
• Sequential Immunochemotherapy Treatment with Pembrolizumab Plus Dendritic Cell (DC) Vaccine Followed by Trifluridine/Tipiracil Plus Bevacizumab in Refractory Mismatch-repair-proficient (pMMR) or Microsatellite-stable (MSS) Metastatic Colorectal Cancer — RECRUITING · PHASE2
• Gut Microbiome Dynamics in Metastasized or Irresectable Colorectal Cancer — RECRUITING
• Molecular Characterisation of Colorectal Cancer Peritoneal Metastases — RECRUITING
• Safety and Efficacy of Fruquintinib Plus Chidamide and Sintilimab in the Third and Later Line Treatment of MSS/pMMR Metastatic Colorectal Cancer — RECRUITING · PHASE2
• PRELUDE-1 (Prospective Evaluation of Radiotherapy-induced Biologic Effects in Colorectal Cancer Oligometastatic Patients with LUng-limited Disease: Evolution of Cancer Genetics and Regulatory Immune Cells) — RECRUITING · NA
• A Study of NILK-2301 in Patients with Locally Advanced or Metastatic Low Tumor Volume (LTV) Colorectal Cancer — RECRUITING · PHASE1
• Cetuximab, Irinotecan, Toripalimab in RAS/BRAF Wild-type Ultraselected Right-sided Colorectal Cancer Study — RECRUITING · PHASE2
• Living Donor Liver Transplantation With Two Stage Hepatectomy for Patients With Isolated, Irresectable Colorectal Liver Metastases — RECRUITING · NA
• Exploration of Therapeutic Strategies for NeoRAS Wild-type Metastatic Colorectal Cancer Based on Circulating Tumor DNA — RECRUITING · PHASE2
• Early Detection of Treatment Failure in Metastatic Colorectal Cancer Patients — RECRUITING
• Explore Biomarkers Associated With Prognosis of Recurrent and Metastatic CRC After Surgery by Multi-omics Methods — RECRUITING
• XNW27011 Study of Advanced Solid Tumor Subjects Who Failed Standard Therapies. — ACTIVE_NOT_RECRUITING · PHASE1

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