CRC Clinical Trials

83 clinical trials for CRC across international registries, including 31 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• First in Human Study of TUB-030 in Patients With Advanced Solid Tumors — RECRUITING · PHASE1
• A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer — RECRUITING · PHASE3
• Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors — RECRUITING · PHASE1
• Feasibility of a Multi-Channel Intervention to Promote Colorectal Cancer Screening Among American Indians in Oklahoma — RECRUITING · NA
• Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors — RECRUITING · PHASE1
• A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer — RECRUITING · PHASE1
• PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer — RECRUITING · PHASE2
• Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors — RECRUITING · PHASE1
• cfDNA 5mC/5hmC Biomarkers to Predict Chemotherapy Response in Metastatic Colorectal Cancer — RECRUITING
• Development of a cfDNA 5mC/5hmC-based Biomarker Panel to Predict Targeted Therapy Efficacy in mCRC — RECRUITING
• A Study of a Urine Test to Detect Colorectal Cancer — RECRUITING
• A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression — RECRUITING · PHASE1
• A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations — RECRUITING · PHASE1
• BBO-11818 in Adult Subjects With KRAS Mutant Cancer — RECRUITING · PHASE1
• Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing — RECRUITING
• A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors — RECRUITING · PHASE1
• Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer — RECRUITING · PHASE2
• A Phase Ib/II Trial of HS-20110 Combination Therapies in Advanced Colorectal Cancer Patients. — RECRUITING · PHASE1
• A Prospective Study to Evaluate the Performance of a Real-time System in the Estimation of Colorectal Polyp Size — RECRUITING · NA
• A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies — RECRUITING · PHASE1
• An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia. — RECRUITING · PHASE2
• Neoadjuvant SHR-1701 Plus Chemoradiotherapy for Locally Advanced Rectal Cancer — RECRUITING · PHASE2
• Validation of High-Throughput Large-Format Tissue Preprocessing for Lung and Colorectal Cancer — RECRUITING
• A Phase 1 Study of TGI-5 as Monotherapy and in Combination With Nivolumab in Subjects With Locally Advanced/Metastatic Solid Tumors — RECRUITING · PHASE1
• A Prospective, Safety, and Efficacy Clinical Trial of Pressurized Intraperitoneal Aerosol Therapy for Peritoneal Metastasis of Colorectal Cancer — RECRUITING · PHASE1
• Identification of New Non-invasive, Predictive, and Diagnostic Biomarkers for Colorectal Cancer — RECRUITING
• A Study of GFH375 Combined With Cetuximab or Chemotherapy in Participants With Solid Tumors Harboring KRAS G12D Mutation — RECRUITING · PHASE1
• The Phase 1b/IIa, Open-label, Dose Escalation and Dose Expansion to Evaluate Safety, Tolerability, and Preliminary Efficacy of the Combination of HCB101, Cetuximab/Bevacizumab, and FOLFOX/FOLFIRI in Advanced or Metastatic Colorectal Cancer — RECRUITING · PHASE1
• A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression — RECRUITING · PHASE1
• An Exploratory Study on Gene Methylation Detection of Colorectal Cancer — RECRUITING
• A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors — RECRUITING · PHASE1
• Recombinant Vaccinia Virus Administered Intravenously in Patients With Metastatic, Refractory Colorectal Carcinoma — COMPLETED · PHASE1
• A Multicenter Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors. — NOT_YET_RECRUITING · NA
• Efficacy and Safety of Retlirafusp Alfa Plus Bevacizumab and Chemotherapy With or Without Short-Course Radiotherapy in Patients With CRCLM — NOT_YET_RECRUITING · PHASE2
• Efficacy and Safety of Tunlametinib Combination Therapy in the Treatment of Second-line and Above Metastatic Colorectal Cancer — NOT_YET_RECRUITING · PHASE2
• Monocentric Retrospective and Prospective Observational Study of Patients With Colorectal Cancer — NOT_YET_RECRUITING
• Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation — ACTIVE_NOT_RECRUITING · PHASE2
• Noninvasive Early Diagnosis of Colorectal Cancer Using Odor-Targeted Capture, Point-of-Care Testing, and Intelligent Analysis — NOT_YET_RECRUITING
• Autologous CAR-T Cells (WD-01) for Metastatic Colorectal Cancer — SUSPENDED · PHASE1
• Universal CAR-T Cells (REVO-UWD-01) for Metastatic Colorectal Cancer — SUSPENDED · PHASE1
• Intratumoral Budding (ITB) in Preoperative Biopsies of Colon and Rectal Cancer — COMPLETED
• Oncolytic Virus (H101) + SBRT + Chemotherapy + Targeted Therapy + Immunotherapy for Unresectable CRLM — NOT_YET_RECRUITING · PHASE2
• Study of Cabozantinib Plus TAS102 in mCRC as Salvage Therapy — COMPLETED · PHASE1
• Study of NGM707 in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies — WITHDRAWN · PHASE2
• SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases — NOT_YET_RECRUITING
• Safety and Efficacy of Neoantigen-Based Personalized Immunotherapy as Consolidation Therapy After Standard Adjuvant Treatment in Resectable Stage III Colorectal Cancer or Non-Small Cell Lung Cancer — COMPLETED · PHASE1
• JAB-21822 Activity in Adult Patients With Advanced Solid Tumors Harboring KRAS G12C Mutation — COMPLETED · PHASE1
• Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors — ACTIVE_NOT_RECRUITING · PHASE1
• A Study to Characterize the Safety, Tolerability, and Preliminary Efficacy of CFT1946 as Monotherapy and Combination Therapy in Subjects With BRAF V600 Mutant Solid Tumors — COMPLETED · PHASE1
• A Single-Arm, Open-Label, Multicenter Phase I/II Clinical Study of GFH276 in Patients With RAS-Mutant Advanced Solid Tumors — NOT_YET_RECRUITING · PHASE1

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