Critical Limb Ischemia Clinical Trials

240 clinical trials for Critical Limb Ischemia across international registries, including 25 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• CRUSH PAD: Real-world Outcomes Following Use of Shockwave Intravascular Lithotripsy (IVL) Technology in Calcified Common Femoral Lesions — RECRUITING
• Use of Thermal Imaging Camera to Assess Perfusion Before and After Vascular Intervention — RECRUITING
• Nutrition in Patient With Critical Limb Ischemia — RECRUITING · PHASE1
• Predictive Value of Systolic Rise Time of the Plantar Arch on the Risk of Major Adverse Limb Events (MALE) and Major Adverse Cardiovascular Events (MACE) in Peripheral Artery Disease (PAD) at Critical Ischaemia Stage — RECRUITING · NA
• FAZA PET/MRI in CLI Patients Pre and Post Revascularization — RECRUITING · NA
• Local And Systemic Macrophage Activation in Coronary and Peripheral Artery Disease — RECRUITING · NA
• PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia — RECRUITING · NA
• Augmenting ischemia-induced vasculo- and angiogenesis after endovascular reperfusion with host-extracted, percutaneously introduced, leucocyte- and platelet-rich fibrin in patients with critical limb ischemia — RECRUITING · PHASE1
• Efficacy and Safety of Stempeucel® in Patients With Critical Limb Ischemia (CLI) Due to Peripheral Arterial Disease — RECRUITING · PHASE4
• Efficacy and Safety of Stempeucel® in Patients With Critical Limb Ischemia (CLI) Due to Buerger's Disease — RECRUITING · PHASE4
• Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Knee — RECRUITING · PHASE3
• Follow-up Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-L) — RECRUITING
• Initial Feasibility Study of the STENTiT Resorbable Fibrillated Scaffold (RFS). The RFS is Intended to Restore Lumen Patency and Blood Flow to Infrapopliteal Arteries. The RFS is a Fully Electrospun Tubular Device With a Fibrillated Microarchitecture and Designed for Transcatheter Delivery — RECRUITING · NA
• Pressure (Fractional Flow Reserve) and Flow (Vascular Flow Reserve) Measurements During Peripheral Arterial Interventions — RECRUITING
• Serrantor OCT Study — RECRUITING · NA
• miRNAs in Critical Limb Ischemia (miRNACLI) — RECRUITING
• TP03HN106 in Patients With Critical Limb Ischemia — RECRUITING · PHASE2
• Additional Hyperbaric Oxygen After Lower Extremity Amputation — RECRUITING · NA
• Safety, Tolerability, and Biodistribution of [89Zr]Zr-DFO-APAC in Subjects With PAOD/CLI and Healthy Volunteers (Acronyms: 89Zr = Zirconium-89, DFO = Desferrioxamine, APAC = AntiPlatelet AntiCoagulant, PET/CT = Positron Emission Tomography/Computed Tomography) — RECRUITING · PHASE1
• Acceleration Time Assessment for Prediction of Critical Limb Ischemia — RECRUITING
• Evaluation of the MAGNITUDE® Bioresorbable Drug-Eluting Scaffold in the Treatment of Patients With Below the Knee Disease in Australia — RECRUITING · NA
• Prospective Cohort of Patients With Critical Limb Ischemia Undergoing Revascularization — RECRUITING
• Leg Ischaemia Management Collaboration — RECRUITING
• "EVALUATION OF PROGNOSTIC VALUE OF 18F-FLUOROAZOMYCIN ARABINOSIDE (FAZA) — RECRUITING
• The Role of Retrograde Access in The Management of Critical Lower Limb Ischemia — RECRUITING
• Trial to Assess Chelation Therapy in Critical Limb Ischemia — ACTIVE_NOT_RECRUITING · PHASE3
• MOTIV BTK Randomized Controlled Trial — ACTIVE_NOT_RECRUITING · NA
• Heat Therapy for Peripheral Arterial Disease (HEATPAD) — WITHDRAWN · NA
• A Prospective Single-Arm Multicenter StuDy of the BarE TEmporary SPur StEnt System foR the tREatment of Vascular Lesions Located in the infrapoplitEal Arteries beLow the Knee (DEEPER REVEAL) — COMPLETED · NA
• Single Versus Multiple Vessels Endovascular Tibial Arteries Revascularization for Critical Limb Ischemia — COMPLETED · NA
• LIFE-BTK PK Sub-study — ACTIVE_NOT_RECRUITING · NA
• Percutaneous Deep Vein Arterialization Post-Market Study — COMPLETED · NA
• Drug Eluting Temporary Spur Stent System vs Percutaneous Balloon Angioplasty for the Treatment of Critical Limb Ischemia — NOT_YET_RECRUITING · NA
• PROMISE International — COMPLETED · NA
• LIFE-BTK Randomized Controlled Trial — ACTIVE_NOT_RECRUITING · NA
• Tolerance study of allogeneic of Adipose tissue derived mesenchymal Stroma/stem Cells (AdMSC) transplantation in patients with critical limb ischemia — TERMINATED · PHASE1
• Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia — COMPLETED · PHASE2
• Safety Study of Gene Therapy in Treating Critical Leg Ischemia — COMPLETED · PHASE1
• Diagnostic Tools to Establish the Presence and Severity of Peripheral Arterial Disease in People With Diabetes — COMPLETED
• DCB Outcomes After Plain or Scoring Balloon for Vessel Preparation in Patients With Femoropopliteal Arterial Disease — COMPLETED · NA
• Swedish Drug-elution Trial in Peripheral Arterial Disease — ACTIVE_NOT_RECRUITING · NA
• Medium-term Results of Lower Limb Arterial Bypass — COMPLETED
• Intima Versus Adventitia Drug Delivery to Elucidate Mechanisms of Restenosis: Magnetic Resonance Imaging — COMPLETED · PHASE4
• IN.PACT BTK Randomized Study to Assess Safety and Efficacy of IN.PACT 014 vs. PTA — COMPLETED · NA
• BEST vCLI Registry — COMPLETED
• Comprehensive Limb Evaluation and Arterial Revascularization With Toe Pressure Optimization Registry — NOT_YET_RECRUITING · NA
• Effect of Environmental Temperature on Vascular Ultrasound Vein Scan Measurements — NOT_YET_RECRUITING
• Cost Analysis of Vascular Surgical Techniques — COMPLETED
• Imaging-Guided Vessel Sizing in the Tibial Arteries — COMPLETED
• Ultrasound-Guided Sciatic Popliteal Nerve Block vs. Erector Spinae Plane Block in Endovascular Management of CLI — COMPLETED

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