Depression - Major Depressive Disorder Clinical Trials

180 clinical trials for Depression - Major Depressive Disorder across international registries, including 78 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder — RECRUITING · PHASE3
• Health and Work Ability Following Inpatient Treatment for Stress-related Disorders - Follow-up Study of the HARMODI Cohort — RECRUITING
• Psilocybin to Treat Depression in Spinal Cord Injury — RECRUITING · PHASE1
• Brief Trial of ACT-i for Adults With Chronic Insomnia — RECRUITING · NA
• Lumateperone for Late-Life Depression — RECRUITING · PHASE3
• ipRGC as a Potential Biomarker for Predicting Transcranial Magnetic Stimulation Treatment Response in Major Depressive Disorder — RECRUITING · NA
• Optimizing Treatment for Depressed Parents of Children With Emotional and Behavioural Problems — RECRUITING · NA
• Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking — RECRUITING · NA
• Modulating Spinal Interoceptive Pathways to Evaluate Their Role and Therapeutic Potential in MDD Symptomatic Domains — RECRUITING · PHASE1
• Virtual Reality-Enhanced Behavioral Activation for Older Adults With Depression — RECRUITING · NA
• Resolving Early Life Stress: Psychotherapy Outcomes and Neurobiology in Complex Depression — RECRUITING · NA
• Intern Health Study 2026 — RECRUITING · NA
• EEG Prediction and Clinical Efficacy of tDCS in Major Depression — RECRUITING · NA
• Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for Depression — RECRUITING · NA
• Longitudinal Study on the Sustainability of Transcranial Magnetic Stimulation Protocols - Biomarkers — RECRUITING
• Enhancing Slow Wave Sleep in Depression — RECRUITING · NA
• Mindfulness-based Psilocybin Therapy for PTSD — RECRUITING · PHASE2
• Analgesic Efficacy of Multisite rTMS in Fibromyalgia Patients — RECRUITING · NA
• HIV-Mental Illness Stigma Reduction and Outcomes in Malawi — RECRUITING · NA
• Effects of Concurrent and Consecutive Repetitive Transcranial Magnetic Stimulation (rTMS) and Cognitive Bias Modification (CBM) — RECRUITING · NA
• Intervention to Reduce HIV Related Stigma Among Pregnant and Postpartum Women — RECRUITING · NA
• Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use — RECRUITING · NA
• Group-based ACT for Psychological Distress of Young People — RECRUITING · NA
• Flumazenil for Benzodiazepine Reversal in Electroconvulsive Therapy — RECRUITING · NA
• Feasibility, Safety, and Preliminary Clinical Efficacy of Magnetic Resonance Imaging-guided Repetitive Transcranial Magnetic Stimulation (rTMS) in Adolescents With Depression: A Randomized, Double-Blind, Controlled Pilot Study — RECRUITING · NA
• Stratified Pharmacological Approaches for Regulating Circuit-Level Effects — RECRUITING · PHASE2
• AI-Guided CBT for Depression and Anxiety — RECRUITING · NA
• Feasibility and Acceptability of an E-learning Dialectical Behavior Therapy Skills Course — RECRUITING · NA
• Personalized Ultrasonic Brain Stimulation for Depression (R61) — RECRUITING · PHASE1
• Integrating Digital Phenotypes and AI-Driven Cognitive-Behavioral Therapy: Advancing Precision Medicine in Depression Through Digital Medicine — RECRUITING · NA
• IMST for Dementia Risk Reduction — RECRUITING · NA
• Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects — RECRUITING · PHASE1
• Nutritional Intervention for College Students With Depression — RECRUITING · NA
• Brain Imaging of Cognition Inn Schizophrenia and Depression — RECRUITING
• Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort — RECRUITING
• TDM-Guided Treatment With SSRIs in Hospitalized Adults and Children — RECRUITING · PHASE4
• Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot — RECRUITING · NA
• Behavioral Health Collaborative Care Model in an ICU Recovery Clinic — RECRUITING · NA
• Open-Label Psilocybin Study in Transdiagnostic Population — RECRUITING · PHASE1
• ACT_for Alcohol Use Disorder and Depression — RECRUITING · NA
• A Novel Blood Test as a Biomarker in Mental Health — RECRUITING
• Virtual Reality-Based Mindfulness as an Adjunct to Treatment as Usual in Treatment-Resistant Depression — RECRUITING · NA
• Fluoxetine on Emotional Experience (FLEX) Study — RECRUITING · NA
• Epigenetic Enhancement of Cognitive Training in Aging Mood Disorder Populations — RECRUITING · NA
• Clinical Impact of an Anti-Inflammatory Diet in Anxiety and Depression With AI — RECRUITING · NA
• No Time to Wait: Single Session Intervention — RECRUITING · NA
• Real-world Clinical Response to Trazodone in Italy, Poland, and Romania — RECRUITING
• Accelerated vs. Conventional Theta Burst Stimulation for Late-life Depression — RECRUITING · NA
• The Effectiveness and Efficacy of an Online Cognitive Behavioral Psychotherapeutic Program — RECRUITING · NA
• AtWork: The Relation Between Cognitive Functioning, Common Mental Disorders and Work Functioning — RECRUITING

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