Diffuse Intrinsic Pontine Glioma Clinical Trials

89 clinical trials for Diffuse Intrinsic Pontine Glioma across international registries, including 25 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0 — RECRUITING · PHASE3
• Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas — RECRUITING · PHASE1
• Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). — RECRUITING · PHASE2
• C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B) — RECRUITING · PHASE1
• Atovaquone Combined With Radiation in Children With Malignant Brain Tumors — RECRUITING · PHASE1
• PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy — RECRUITING · PHASE1
• Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion — RECRUITING · PHASE1
• Combination Therapy for the Treatment of Diffuse Midline Gliomas — RECRUITING · PHASE2
• Study of Olutasidenib and Temozolomide in HGG — RECRUITING · PHASE2
• Targeted Pediatric High-Grade Glioma Therapy — RECRUITING
• Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant — RECRUITING · PHASE2
• A Study of VRT106 in Combination With Radiotherapy in Adult Patients With Diffuse Midline Glioma / Diffuse Intrinsic Pontine Glioma — RECRUITING · PHASE2
• PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma — RECRUITING · PHASE2
• Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors — RECRUITING · PHASE1
• A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion — RECRUITING · PHASE1
• rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG — RECRUITING · PHASE1
• FUS Etoposide for DMG — RECRUITING · PHASE1
• Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age — RECRUITING · PHASE1
• International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository — RECRUITING
• Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG — RECRUITING · PHASE1
• GD2-CAR T Cells for Pediatric Brain Tumours — RECRUITING · PHASE1
• Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma — RECRUITING
• Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma — RECRUITING · PHASE1
• Oncolytic Virus Ad-TD-nsIL12 for Primary Pediatric Diffuse Intrinsic Pontine Glioma — RECRUITING · PHASE1
• International cooperative Phase III trial of the HIT-HGG study group for the treatment of high grade glioma, diffuse intrinsic pontine glioma, and gliomatosis cerebri in children and adolescents < 18 years. — RECRUITING
• A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas — ACTIVE_NOT_RECRUITING · PHASE1
• Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors — COMPLETED
• Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG) — NOT_YET_RECRUITING · PHASE2
• IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG) — NOT_YET_RECRUITING · PHASE1
• Study of Relatlimab and Nivolumab (Opdualag) in Replication Repair Deficient HGG and DIPG — NOT_YET_RECRUITING · PHASE2
• Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma — COMPLETED · PHASE1
• A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma — ACTIVE_NOT_RECRUITING · PHASE1
• Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG — ACTIVE_NOT_RECRUITING · NA
• A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma — ACTIVE_NOT_RECRUITING · PHASE1
• Cilengitide in Combination With Irradiation in Children With Diffuse Intrinsic Pontine Glioma — COMPLETED · PHASE1
• Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG — ACTIVE_NOT_RECRUITING · PHASE2
• Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors — ACTIVE_NOT_RECRUITING · PHASE1
• A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer — ACTIVE_NOT_RECRUITING · PHASE1
• Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I) — TERMINATED · PHASE1
• A Study of Atengenal and Astugenal in Diffuse, Intrinsic Pontine Glioma (DIPG) — SUSPENDED · PHASE2
• A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG — TERMINATED · PHASE1
• 9-ING-41 in Pediatric Patients With Refractory Malignancies. — TERMINATED · PHASE1
• Fimepinostat in Treating Brain Tumors in Children and Young Adults — ACTIVE_NOT_RECRUITING · PHASE1
• Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG) — TERMINATED · PHASE1
• Neoantigen Vaccine Therapy Against H3.3-K27M Diffuse Intrinsic Pontine Glioma — COMPLETED · PHASE1
• Multicenter, open label study using molecularly determined targeted therapies in children 3-18 years of age with DIPG (diffuse intrinsic pontine glioma- DIPG)- DIPGen — TERMINATED · PHASE2
• REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma — TERMINATED · PHASE1
• Vorinostat and Temsirolimus With or Without Radiation Therapy in Treating Younger Patients With Newly Diagnosed or Progressive Diffuse Intrinsic Pontine Glioma — COMPLETED · PHASE1
• Gemcitabine in Newly-Diagnosed Diffuse Intrinsic Pontine Glioma — COMPLETED · PHASE1
• ONC201 in Pediatric H3 K27M Gliomas — TERMINATED · PHASE1

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