Dravet Syndrome Clinical Trials

91 clinical trials for Dravet Syndrome across international registries, including 17 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome — RECRUITING · PHASE3
• A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS) — RECRUITING · PHASE3
• ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome — RECRUITING · PHASE1
• A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome — RECRUITING · PHASE3
• A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome — RECRUITING · PHASE1
• The FINTEPLA as an Anti-SUDEP Therapy in Dravet Syndrome Project — RECRUITING · PHASE4
• EMPEROR: A Multicenter, Randomized, Double-blind, Sham-controlled, Parallel Group, Phase 3 Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen (STK-001) in Patients with Dravet Syndrome — RECRUITING · PHASE3
• A Study to Evaluate the Safety and Pharmacokinetics of RC001 in Children With Dravet Syndrome — RECRUITING · PHASE1
• Assessment of Safety of the Use of Fenfluramine in Children With Dravet Syndrome Under 24 Months of Age — RECRUITING · PHASE4
• A PET-MRI Study of Serotoninergic Brainstem Pathway in Patients With Dravet Syndrome — RECRUITING · NA
• Multicentre Real-life Follow-up Study of Rare Epileptic Syndromes in Children and Adolescents — RECRUITING
• Longitudinal Study of Phenotypic and Developmental Severity in Patients With Dravet Syndrome With SCN1A Gene Mutation — RECRUITING
• BMB-101 in Absence Epilepsy and DEE — RECRUITING · PHASE2
• A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO INVESTIGATE THE EFFICACY, SAFETY, AND TOLERABILITY OF LP352 IN THE TREATMENT OF SEIZURES IN CHILDREN AND ADULTS WITH DRAVET SYNDROME — RECRUITING · PHASE3
• GABA Biomarkers in Dravet Syndrome — RECRUITING
• A 20-WEEK MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF EPX-100 (CLEMIZOLE HYDROCHLORIDE) AS ADJUNCTIVE THERAPY IN CHILDREN AND ADULT PARTICIPANTS WITH DRAVET SYNDROME (ARGUS TRIAL) — RECRUITING
• CANNABIDIOL IN CHILDREN WITH REFRACTORY EPILEPTIC ENCEPHALOPATHY: A PHASE 1 OPEN LABEL DOSE ESCALATION STUDY — RECRUITING · PHASE1
• A MULTICENTRE RANDOMIZED CONTROLLED TRIAL COMPARING TOPIRAMATE, STIRIPENTOL AND CLOBAZAM AS ADJUNCTIVE THERAPY TO VALPROATE AND CLOBAZAM IN PAEDIATRIC PATIENTS WITH DRAVET'S SYNDROME (SMEI) NOT ADEQUATELY CONTROLLED WITH CLOBAZAM AND VALPROATE, AND AUXILIARY PHARMACOGENETIC STUDY — ACTIVE_NOT_RECRUITING · PHASE3
• A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome — ACTIVE_NOT_RECRUITING · PHASE3
• Prospective German Real World Epidyolex® Beyond Seizure Study - PROGRESS — OTHER
• Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution — ACTIVE_NOT_RECRUITING · PHASE4
• Phase 1-2, Open-Label, Single and Multiple Ascending Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION337 in Patients with Dravet Syndrome — NOT_YET_RECRUITING · PHASE2
• Early Check: Expanded Screening in Newborns — ACTIVE_NOT_RECRUITING
• A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome — TERMINATED · PHASE3
• A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome — ACTIVE_NOT_RECRUITING · PHASE1
• A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Investigate the Efficacy, Safety, and Tolerability of LP352 in the Treatment of Seizures in Children and Adults with Dravet Syndrome — TERMINATED · PHASE3
• Epidyolex® in Lennox Gastaut, Dravet Syndrome and Tuberous Sclerosis Complex: an Observational Study in ITALY — ACTIVE_NOT_RECRUITING
• Applicability and Effectiveness of Remote Occupational Therapy — COMPLETED
• Fenfluramine for Adult Dravet Patients — TERMINATED · PHASE3
• Treatment of Dravet Syndrome With Fenfluramine (Expanded Access Protocol) — OTHER
• A Study of Soticlestat in Adults and Children With Rare Epilepsies — TERMINATED · PHASE2
• A Study to Investigate the Transition of Children From 'Artisanal" Cannabidiol (CBD) to Epidiolex — NOT_YET_RECRUITING · PHASE4
• PHASE 1-2, OPEN-LABEL, SINGLE AND MULTIPLE ASCENDING DOSE STUDY TO EVALUATE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF INTRATHECALLY-ADMINISTERED ION337 IN PATIENTS WITH DRAVET SYNDROME — NOT_YET_RECRUITING · PHASE1
• An Open-Label Extension Study of STK-001 for Patients With Dravet Syndrome — ACTIVE_NOT_RECRUITING · PHASE2
• A 20-Week Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of EPX-100 (Clemizole Hydrochloride) as Adjunctive Therapy in Children and Adult Participants with Dravet Syndrome (ARGUS Trial) — TERMINATED · PHASE3
• Treatment Plan to Provide Expanded Access to Stiripentol for Patients With Dravet Syndrome — OTHER
• Neurodevelopmental Impact of Epilepsy on Autonomic Function in Dravet Syndrome — ACTIVE_NOT_RECRUITING · NA
• Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy — COMPLETED · PHASE2
• A Study to Investigate the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution in Children and Adults With Epileptic Encephalopathy Including Dravet Syndrome and Lennox-Gastaut Syndrome — COMPLETED · PHASE3
• A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (Australia Only) — ACTIVE_NOT_RECRUITING · PHASE1
• Clinical Utility of Reduced EEG Home Monitoring in Fenfluramine Titration for Dravet and LGS — NOT_YET_RECRUITING · NA
• Bioavailability of Stiripentol After Single Oral Dose of Capsule vs Suspension in Healthy Subjects (STILIQ) — COMPLETED · PHASE1
• A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to Fenfluramine — TERMINATED · PHASE3
• An Open-Label Extension Trial to Assess the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride HCl) Oral Solution in Children and Young Adults With Dravet Syndrome — COMPLETED · PHASE3
• Bioavailability study of stiripentol after single oral administration of two different formulations (capsule and oral suspension) in 24 healthy subjects — OTHER · PHASE1
• An Open-Label Study to Investigate the Safety of Single and Multiple Ascending Doses in Children and Adolescents With Dravet Syndrome — COMPLETED · PHASE1
• A Study to Gather Information About Overall Occurrence and New Cases of Dravet and Lennox-Gastaut Syndromes in Children, Teenagers and Adults in Spain — COMPLETED
• Intermediate-Size Expanded Access Protocol (EAP) for LP352 — OTHER
• A Study of Soticlestat as an Add-on Therapy in Children and Young Adults With Dravet Syndrome — COMPLETED · PHASE3
• CBD Delivery with the A-Synaptic GT4 Transdermal Delivery System in with Dravet Syndrome And/or Lennox-Gastaut Syndrome — NOT_YET_RECRUITING · PHASE1

Refine this search