Esophageal Squamous Cell Carcinoma Clinical Trials

397 clinical trials for Esophageal Squamous Cell Carcinoma across international registries, including 112 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Neoadjuvant Chemoradiotherapy Combined With CTLA-4 Monoclonal Antibody Plus PD-1 Monoclonal Antibody for Locally Advanced Esophageal Cancer — RECRUITING · PHASE2
• A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas — RECRUITING · PHASE1
• A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01) — RECRUITING · PHASE3
• Surgery vs. Radical Chemoradiotherapy for Esophageal SCC After Neoadjuvant Immunochemotherapy — RECRUITING · PHASE3
• Novel Strategy for Early Detection of Esophageal Squamous Cell Carcinoma — RECRUITING · NA
• A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors — RECRUITING · PHASE1
• A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma in Racial and Ethnic Minority Patients in the United States — RECRUITING · PHASE2
• A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors — RECRUITING · PHASE1
• Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors — RECRUITING · PHASE1
• Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis — RECRUITING · PHASE1
• A Study of BL-B01D1 in Combination With Tislelizumab ±5-Fluorouracil Versus Platinum-Based Chemotherapy Plus Tislelizumab as First-line Treatment in Patients With Unresectable, Locally Advanced Recurrent or Metastatic Esophageal Squamous Cell Carcinoma(PANKU-Esophagus02) — RECRUITING · PHASE2
• PD-1 Inhibitors Combined With Local Therapy at Different Timings in Oligometastatic ESCC — RECRUITING
• Neoadjuvant Cardonilizumab Combined With Neoadjuvant Chemoradiotherapy Can Resect Locally Advanced Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE2
• Predicting Postoperative Chemotherapy Efficacy in Patients With Esophageal Squamous Cell Carcinoma — RECRUITING
• A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer — RECRUITING
• Becotatug Vedotin ± Anti-PD-1 in Pretreated Advanced ESCC — RECRUITING · PHASE2
• A Study of Sigvotatug Vedotin in Advanced Solid Tumors — RECRUITING · PHASE1
• Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06) — RECRUITING · PHASE1
• A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors — RECRUITING · PHASE1
• A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B) — RECRUITING · PHASE1
• Intestinal Low-Dose Radiotherapy Plus Immunochemotherapy for Conversion of Borderline Resectable/Unresectable Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE2
• Evaluation of Skin Tests in Biotherapy Allergies — RECRUITING · NA
• A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types — RECRUITING · PHASE1
• First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors — RECRUITING · PHASE1
• Adebrelimab Combined With Neoadjuvant Chemotherapy in Borderline Resectable Locally Advanced Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE2
• Time-of-Day of Immunotherapy Infusion in Neoadjuvant Immunochemotherapy for Thoracic ESCC — RECRUITING · PHASE2
• A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations — RECRUITING · PHASE1
• Phase II Study Evaluating Safety and Efficacy of Tislelizumab for Elderly Patients Unfit for Chemotherapy, With Advanced Esophageal Squamous-cell Carcinoma — RECRUITING · PHASE2
• Adebrelimab Combined With Neoadjuvant Chemoradiotherapy for Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE2
• A Phase 2 Open-Label, Umbrella Platform Design Study of Investigational Agent(s) in Participants With 2L/3L Unresectable Locally Advanced or Metastatic Esophageal Cancer: KEYMAKER-U06 Substudy 06F — RECRUITING · PHASE2
• A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors — RECRUITING · PHASE1
• Infiltration Pattern of Locally Advanced ESCC — RECRUITING
• Induction Chemo-Immunotherapy + Radiotherapy vs Concurrent Chemoradiotherapy for Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE2
• QLC5508 vs. Chemotherapy in Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE3
• Intensive Nutritional Support in Conversion Therapy for Locally Advanced Unresectable ESCC — RECRUITING · PHASE2
• Efficacy and Safety of Adebrelimab Combined With Chemoradiotherapy in Patients With Unresectable Locally Advanced or Postoperative Recurrent Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE2
• 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors — RECRUITING · PHASE1
• KC1036 in Combination With PD-1 Antibody and Platinum-based Chemotherapy for First-line Advanced Esophageal Cancer — RECRUITING · PHASE2
• Study of Tislelizumab Combined With Chemoradiotherapy and Surgery for Unresectable Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE2
• Neoadjuvant Adebrelimab Plus Chemotherapy for Esophageal Cancer: A Clinical Study — RECRUITING · PHASE2
• A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC — RECRUITING · PHASE1
• Registry Platform Gastric/Esophageal Cancer (SAPHIR) — RECRUITING
• Radiotherapy Combined With Immunochemotherapy in Metastatic Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE2
• MR-Guided Radiotherapy Dose Escalation Trial for Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE1
• Neoadjuvant Immunotherapy Combined With Chemotherapy Sequenced With Endoscopic Resection for Esophageal Cancer (Endosurgery-02) — RECRUITING · PHASE1
• Nimotuzumab,Camrelizumab, and Neoadjuvant Chemotherapy（nCT） in the Treatment of Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE2
• The Efficacy and Safety of Iparomlimab and Tuvonralimab Injection Combined With Chemotherapy as the First-line Treatment for Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE2
• Efficacy and Safety of Neoadjuvant Envafolimab Combined With Albumin-bound Paclitaxel and Carboplatin for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE2
• Adbelimumab Combined With Chemotherapy and Apatinib in Patients With Resectable Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE2
• Surufatinib in Combination With Neoadjuvant Chemo-immunotherapy and Concurrent Chemoradiotherapy for Patients With Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma — RECRUITING · PHASE2

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