Familial Hypercholesterolemia Clinical Trials

108 clinical trials for Familial Hypercholesterolemia across international registries, including 22 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• 2-Hydroxybenzylamine (2-HOBA) to Reduce HDL Modification and Improve HDL Function in Familial Hypercholesterolemia (FH) — RECRUITING · PHASE2
• Child-Parent Familial Hypercholesterolemia Screening — RECRUITING
• National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry — RECRUITING
• Comparing Direct vs Indirect Methods for Cascade Screening — RECRUITING · NA
• The ORIGIN-FH Study — RECRUITING · NA
• Improving Diagnosis and Clinical Management of Familial Hypercholesterolemia Through Integrated Machine Learning, Implementation Science, and Behavioral Economics — RECRUITING · NA
• EAS Familial Hypercholesterolaemia Studies Collaboration — RECRUITING
• Familial Hypercholesterolemia Interpretive Comment - Nudging to Detection. — RECRUITING · NA
• Penn Family Screening for Familial Hypercholesterolemia — RECRUITING · NA
• Collaborative Approach to Reach Everyone With Familial Hypercholesterolemia (CARE-FH) — RECRUITING · NA
• PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ZODASIRAN IN ADOLESCENT AND ADULT SUBJECTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (YOSEMITE) — RECRUITING · PHASE3
• Atlantic Lipid Lowering Treatment Optimization Program — RECRUITING · NA
• Clinical Exploration Trial of YOLT-101 in the Treatment of Familial Hypercholesterolemia (FH) — RECRUITING · PHASE1
• Early Detection of Familial Hypercholesterolemia in Children — RECRUITING
• Long-term Efficacy and Safety of OLE LIB003 in HoFH, HeFH, and High-risk CVD Patients Requiring Further LDL-C Reduction — RECRUITING · PHASE3
• PMMHRI - Familial Hypercholesterolemia Registry — RECRUITING
• Lipid Transport Disorder Italian Genetic Record (LIPIGEN) — RECRUITING
• Familial Hypercholesterolemia Canada / Hypercholesterolemie Familiale Canada — RECRUITING
• Evaluation of a Digiphysical Screening Method to Identify and Diagnose Familial Hypercholesterolemia — RECRUITING
• AN OPEN-LABEL, SINGLE ARM, MULTICENTER EXTENSION STUDY TO EVALUATE LONG-TERM SAFETY AND TOLERABILITY OF INCLISIRAN IN PARTICIPANTS WITH HETEROZYGOUS OR HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA WHO HAVE COMPLETED THE PEDIATRIC ORION-16, ORION-13, ORION-20, OR ORION-19 STUDIES (VICTORION-PEDS-OLE) — RECRUITING
• Russian Familial Hypercholesterolemia Registry — RECRUITING
• A PLACEBO-CONTROLLED, DOSE-ESCALATION STUDY TO ASSESS THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF SINGLE AND MULTIPLE DOSES OF ISIS 703802, TARGETING ANGPTL3, ADMINISTERED SUBCUTANEOUSLY TO HEALTHY VOLUNTEERS WITH ELEVATED TRIGLYCERIDES AND SUBJECTS WITH FAMILIAL HYPERCHOLESTEROLEMIA — RECRUITING
• The Effect of UrsodeoXyCholicacid (UDCA) and ezetimibe on total faecal steRol ExcreTion and plasma lipid lEvels — ACTIVE_NOT_RECRUITING · PHASE4
• A Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids — COMPLETED · PHASE3
• Greek Registry - Familial Hypercholesterolaemia — COMPLETED
• Cascade Testing In Identifying At-risk Family Members Of Individuals With Familial Hypercholesterolemia (FH) In PCP — NOT_YET_RECRUITING · NA
• An Adapted Brazilian Cardioprotective Diet, Phytosterols and Krill Oil in Familial Hypercholesterolemia (DICA-FH) — ACTIVE_NOT_RECRUITING · NA
• Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia — COMPLETED · NA
• Pediatric Reporting of Adult-Onset Genomic Results — COMPLETED · PHASE1
• A Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017/CORALreef HeFH) — COMPLETED · PHASE3
• Effect of Breastfeeding on Lipid Profile and Cardiovascular Risk Markers in Women With Familial Hypercholesterolemia — ACTIVE_NOT_RECRUITING
• Improved Diagnosis of Familial Hypercholesterolemia Across the Northland (ID-FH) — ACTIVE_NOT_RECRUITING · PHASE3
• Brazilian Cardioprotective Diet, Phytosterols and Krill Oil in Patients With Familial Hypercholesterolemia — COMPLETED · NA
• Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients — COMPLETED · PHASE1
• Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies — COMPLETED · PHASE3
• Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying Therapies — COMPLETED · PHASE3
• A VSA003 Phase 1 Study in Chinese Adult Healthy Volunteers — COMPLETED · PHASE1
• Unravelling the Impact of Diet on Cardiovascular Health in Heterozygous Familial Hypercholesterolemia. — COMPLETED · NA
• Patterns of Inclisiran Use in the Real World: An Analysis of US Databases — COMPLETED
• Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modifying Therapies. — COMPLETED · PHASE3
• The Danish Familial Hypercholesterolemia Organized Coronary Screening Trial — ACTIVE_NOT_RECRUITING · NA
• Genetic Causes of Familial Hypercholesterolemia — ACTIVE_NOT_RECRUITING
• Genetic Testing and Motivational Counseling for FH — ACTIVE_NOT_RECRUITING · NA
• A Study of the Efficacy and Safety of Enclitide Chloride (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-008) — COMPLETED · PHASE2
• Long Term Post Marketing Specified Drug Use Result Survey for Evolocumab in Japan — COMPLETED
• Unravelling the Impact of Diet on Cardiovascular Health in Treated Heterozygous Familial Hypercholesterolemia. — COMPLETED · NA
• The Use of Mobile Health Technology and Behavioral Economics to Encourage Adherence in Adolescents — COMPLETED · NA
• Clinical Exploration Trial of YOLT-101 in the Treatment of Familial Hypercholesterolemia (FH) — OTHER · PHASE1
• Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia) — COMPLETED · PHASE3
• A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-833) — COMPLETED · PHASE3

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