Gastrointestinal Stromal Tumors Clinical Trials

141 clinical trials for Gastrointestinal Stromal Tumors across international registries, including 21 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Study of DCC-2618 in Patients With GIST After at Least 3 Prior Treatments — RECRUITING · PHASE1
• Integrated Cancer Repository for Cancer Research — RECRUITING
• Preoperative Imatinib and Fampridine in KIT Mutant Gastrointestinal Stromal Tumor — RECRUITING · PHASE1
• Rivoceranib Plus Paclitaxel in Patients With Gastrointestinal Stromal Tumor — RECRUITING · PHASE2
• The Efficacy and Safety of Temozolomide in SDH-deficient GIST — RECRUITING · PHASE2
• GIST Oral Paclitaxel(Liporaxel) — RECRUITING · PHASE2
• Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring — RECRUITING · PHASE2
• Imatinib TDM in GIST — RECRUITING · PHASE2
• A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit — RECRUITING · PHASE1
• ctDNA-Guided Sunitinib And Regorafenib Therapy for GIST — RECRUITING · PHASE2
• 5 Years of Adjuvant Imatinib in Patients With Gastrointestinal Stromal Tumor With a High Risk — RECRUITING · PHASE2
• Observational Registry Data on GIST Patients — RECRUITING
• Observational Study, for Quality Assessment, of Sarcoma in European and Latin American Multidisciplinary NETWORK — RECRUITING
• A Multicenter Study of Avapritinib Efficacy and Safety of Metastatic or Unresectable Gastrointestinal Stromal Tumors — RECRUITING
• Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRA — RECRUITING
• Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients — RECRUITING
• Evaluate the Efficacy and Safety of Radiotherapy Combined With Ripretinib in the Treatment of Unresectable Advanced GIST — RECRUITING · NA
• A Cohort Study on the Safety of Laparoscopic Resection of 5cm or Larger Gastric Gastrointestinal Stromal Tumors — RECRUITING
• Clinical Research of Drug Holiday Based on MRD Detection in GIST Patients at High Risk of Recurrence — RECRUITING
• Apatinib Mesylate Versus Standard Second-line TKI in the Treatment of Advanced GIST — RECRUITING · NA
• Prediction of Postoperative Treatment Efficacy and Recurrence Risk of High-risk GIST Based on Liquid Biopsy MRD — RECRUITING
• An open-label, multi-center study to evaluate the efficacy of nilotinib in adult patients with gastrointestinal stromal tumors resistant to imatinib and sunitinib — COMPLETED · PHASE3
• Multicenter, single-arm, two-stage phase II trial of RAD001 (everolismus) with Glivec® in Glivec®-resistant patients with progressive GIST — COMPLETED · PHASE2
• Development of a Multimodal AI System for GIST Management — COMPLETED
• Temozolomide (TMZ) In Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST) — COMPLETED · PHASE2
• Treatment of Patients With Metastatic or Unresectable Gastrointestinal Stromal Tumors in First Line With Nilotinib — COMPLETED · PHASE4
• Phase 2 Study to Evaluate the Efficacy of Regorafenib in Specific GIST Mutation Subsets (KIT Exon 17, 18, or 14 Mutation and SDHB Deficient GIST) in the Post-imatinib Second-line Setting. — ACTIVE_NOT_RECRUITING · PHASE2
• To Explore the Optimal Therapeutic Window for Imatinib in the Adjuvant Treatment of Intermediate and High-risk Gastrointestinal Stromal Tumors — COMPLETED
• Paclitaxel in Patients With GIST With Low P-glycoprotein Expression After Failure of at Least Imatinib and Sunitinib, and Regorafenib. — COMPLETED · PHASE2
• A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer — TERMINATED · PHASE2
• Safety and Efficacy of Avapritinib in Chinese Patients With Gastrointestinal Stromal Tumor (GIST) in the Real World — COMPLETED
• A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib — ACTIVE_NOT_RECRUITING · PHASE3
• A Study of Pimitespib in Combination With Imatinib in Patients With GIST (CHAPTER-GIST-101) — ACTIVE_NOT_RECRUITING · PHASE1
• SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST — ACTIVE_NOT_RECRUITING · PHASE2
• Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies — TERMINATED · PHASE1
• A Study of Avelumab In Combination With Axitinib in Patients With Unresectable/Metastatic Gastrointestinal Stromal Tumor After Failure of Standard Therapy — COMPLETED · PHASE2
• A Study of DCC-2618 (Ripretinib) In Patients With With Advanced Gastrointestinal Stromal Tumors (GIST) — COMPLETED · PHASE2
• Second-line Pharmacotherapy Patterns and Outcomes of Advanced Gastrointestinal Stromal Tumor: A Real-world Study — OTHER
• The Correlation Between Ripretinib Exposure and the Efficacy and Safety in Patients with Advanced GISTs — OTHER
• CGT9486 (Formerly Known as PLX9486) as a Single Agent and in Combination With PLX3397 (Pexidartinib) or Sunitinib in Participants With Advanced Solid Tumors — COMPLETED · PHASE1
• A Phase II, single arm Study of avelumab in combination with Axitinib in Patients with unresectable/metastatic Gastrointestinal Stromal Tumor after failure of standard therapy - AXAGIST — OTHER · PHASE2
• A Drug-drug Interaction Study of Avapritinib and Midazolam — COMPLETED · PHASE1
• Study for Patients Previously Treated in Avapritinib Clinical Trials — COMPLETED · PHASE4
• Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics — ACTIVE_NOT_RECRUITING · NA
• Nilotinib Roll-over Protocol for Patients in Novartis-sponsored Nilotinib Study and Benefiting From Nilotinib Treatment — COMPLETED · PHASE2
• Epacadostat and Pembrolizumab in Patients With GIST — TERMINATED · PHASE2
• A Study of THE-630 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST) — TERMINATED · PHASE1
• DNX-2440 for Resectable Colorectal Liver Metastasis — SUSPENDED · PHASE1
• DS-6157a in Participants With Advanced Gastrointestinal Stromal Tumor (GIST) — TERMINATED · PHASE1
• Efficacy and Safety of Famitinib Versus Sunitinib in the Treatment of Advanced Gastrointestinal Stromal Tumour Patients After Failure of Imatinib — TERMINATED · PHASE3

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