GBM Clinical Trials

74 clinical trials for GBM across international registries, including 17 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII — RECRUITING · PHASE2
• Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM — RECRUITING · PHASE3
• WBSI Guided Personalized Delivery of TTFields — RECRUITING · NA
• Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma — RECRUITING · PHASE1
• Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma — RECRUITING · PHASE2
• Imaging Acetadote Metabolism in Glioblastoma — RECRUITING · PHASE1
• Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma — RECRUITING · PHASE1
• Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma — RECRUITING · NA
• Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM) — RECRUITING · NA
• Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM — RECRUITING · PHASE3
• Sonodynamic Therapy in Patients With Recurrent GBM — RECRUITING · PHASE1
• Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma. — RECRUITING · PHASE1
• Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy — RECRUITING · PHASE1
• Clinical Study on the Treatment of Malignant Brain Glioma by QH104 Cell Injection — RECRUITING · PHASE1
• Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma — RECRUITING · PHASE1
• Evaluate the Efficacy and Safety of ADCV01 As an Add-On Treatment for Primary Glioblastoma Multiforme (GBM) Patients — RECRUITING · PHASE2
• Integrative Analysis of Human Glioblastoma Multiforme — RECRUITING
• A Trial of Belzutifan (PT2977, MK-6482) Tablets In Patients With Advanced Solid Tumors (MK-6482-001) — ACTIVE_NOT_RECRUITING · PHASE1
• A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma — ACTIVE_NOT_RECRUITING · PHASE3
• Safety And Effectiveness Of NaviFUS System With Bevacizumab In Recurrent Glioblastoma — NOT_YET_RECRUITING · NA
• Phase I Pilot Study to Evaluate the Anti-glioblastoma Effect of S-Gboxin in Standard Treatment of Glioblastoma/Diffuse Midline Glioma and Response to Treatment (Regardless of Mutation Status) — SUSPENDED · PHASE1
• Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM) — SUSPENDED · PHASE1
• Surgical Tissue Flap to Bypass the Blood Brain Barrier in GBM — COMPLETED · NA
• Study of LP-184 in Patients With Advanced Solid Tumors — ACTIVE_NOT_RECRUITING · PHASE1
• Ketogenic Diet in Combination With Standard-of-care Radiation and Temozolomide for Patients With Glioblastoma — COMPLETED · PHASE1
• Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma — ACTIVE_NOT_RECRUITING · PHASE1
• Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma — ACTIVE_NOT_RECRUITING · PHASE1
• LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients — COMPLETED · PHASE1
• Surgery and Laser Interstitial Thermal Therapy for Bilateral Glioblastomas — NOT_YET_RECRUITING · NA
• Surgical Nivolumab And Ipilimumab For Recurrent GBM — ACTIVE_NOT_RECRUITING · PHASE1
• A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors — ACTIVE_NOT_RECRUITING · PHASE1
• Niraparib/TTFields in GBM — ACTIVE_NOT_RECRUITING · PHASE2
• Assessment of Novel Metabolic Imaging Modalities as A Predictor Of Therapeutic EfficacyiIn Glioblastoma (GBM) — SUSPENDED · PHASE2
• Infigratinib in Recurrent High-Grade Glioma Patients — TERMINATED · PHASE1
• Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed Glioblastoma — COMPLETED · PHASE1
• Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression — COMPLETED · PHASE2
• VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM — TERMINATED · PHASE3
• Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting — COMPLETED · PHASE2
• Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma — COMPLETED · PHASE1
• Abemaciclib w/Bevacizumab in Recurrent GBM Pts w/Loss of CDKN2A/B or Gain or Amplification of CDK4/6 — TERMINATED · PHASE1
• Study to Evaluate Ibudilast and TMZ Combo Treatment in Newly Diagnosed and Recurrent Glioblastoma — COMPLETED · PHASE1
• A Nomogram for Predicting the Diagnosis of Central Malignant Tumors Based on Preoperative Clinical Characteristics and Laboratory Indicators: — COMPLETED
• Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme — COMPLETED · PHASE2
• A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme — COMPLETED · PHASE1
• Lenvatinib, Pembrolizumab, and Tumor Treating Fields (TTFields) for Second-line Treatment of Glioblastoma — WITHDRAWN · PHASE1
• Methylation Patterns of the NUPR1, MGMT, NDRG2, and GLI1 Genes and Their Impact on Therapeutic Outcome of GBM Patients — COMPLETED
• Single Patient Compassionate Use / Expanded Access L-S-Gboxin (Lyophilized Form of S-Gboxin) for the Treatment of Diffuse Midline Glioma — TERMINATED
• Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant Glioma — NOT_YET_RECRUITING · PHASE1
• Recurrent GBM Treated With Neurosurgical Resection and IORT Using the Xoft Axxent eBx System and Bevacizumab — TERMINATED · PHASE2
• Recurrent GBM With Maximal Neurosurgical Removal and Treatment With IORT — TERMINATED · NA

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