Glioblastoma Clinical Trials

1020 clinical trials for Glioblastoma across international registries, including 206 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells — RECRUITING · PHASE1
• Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII — RECRUITING · PHASE2
• The Effect of Glioblastoma PSMA Expression Following Tumour VEGF Blockade From Bevacizumab — RECRUITING
• PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications — RECRUITING · PHASE1
• Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma — RECRUITING · PHASE3
• Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM — RECRUITING · PHASE3
• Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care — RECRUITING · PHASE3
• A Study to Better Understand the Biological and Molecular Mechanisms Involved in Glioblastoma Recurrence and Progression — RECRUITING
• A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 Gliomas — RECRUITING · PHASE2
• Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression — RECRUITING · PHASE1
• Bortezomib and Temozolomide in Recurrent Grade-4 Glioma Unmethylated MGMT Promoter (BORTEM-17) — RECRUITING · PHASE1
• A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma — RECRUITING · PHASE2
• Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma — RECRUITING · PHASE2
• A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma — RECRUITING · PHASE1
• The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas — RECRUITING · PHASE2
• Characterization of the Blood-Brain Barrier in High-Grade Glioma Through Immunohistochemical, Transcriptional, Fluorescein and Radiological Analyses — RECRUITING · NA
• EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma — RECRUITING · PHASE3
• A Phase I/II Study of IVONESCIMAB in Recurrent Glioblastoma — RECRUITING · PHASE1
• ERAS-801 for the Treatment of Resectable and Progressive or Recurrent or Elderly Newly Diagnosed IDH Wildtype Grade IV Glioblastoma or Gliosarcoma With an EGFR Amplification or Mutation, ERAS801-SARG Trial — RECRUITING · PHASE1
• Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors — RECRUITING · NA
• Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma — RECRUITING · PHASE2
• Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas — RECRUITING · PHASE2
• The Feasibility and Efficacy of Dose Timing (Morning vs Evening) of Temozolomide in the Treatment of Glioblastoma — RECRUITING · NA
• CARv3-TEAM-E T Cells in Glioblastoma — RECRUITING · PHASE1
• DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM) — RECRUITING · PHASE2
• Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures — RECRUITING · PHASE1
• Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion — RECRUITING · PHASE1
• Vortioxetine for Newly Diagnosed Glioblastoma — RECRUITING · PHASE2
• Intensified Adjuvant Therapy for High-Risk Newly Diagnosed Glioblastoma With Subtotal Resection or Short-Term Progression — RECRUITING · PHASE2
• TTFields Plus FET-PET-Guided Stereotactic Radiosurgery Versus TTFields Alone for Recurrent Glioblastoma (Tarrget 2.0) — RECRUITING · NA
• Investigating the Feasibility and Acceptability of an Innovative Interdisciplinary Supportive Care Program: Couples Coping Together Against Cancer — RECRUITING
• A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies — RECRUITING · PHASE1
• Imaging Acetadote Metabolism in Glioblastoma — RECRUITING · PHASE1
• Radiodynamic Therapy (RDT) With Gliolan in Patients With First Recurrence of Brain Tumor — RECRUITING · PHASE1
• Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent Glioblastoma — RECRUITING · PHASE1
• Music Therapy in Newly Diagnosed Glioblastoma After Chemoradiation Therapy (MELODY-GBM) — RECRUITING · NA
• Methimazole in Patients With Progressive Glioblastoma — RECRUITING · PHASE2
• Sitagliptin in Recurrent/Progressive Grade 4 Glioma — RECRUITING · PHASE1
• Dosimetry, Safety, and Efficacy Study of [177Lu]Lu-XT771 in Patients With Recurrent Glioblastoma — RECRUITING · PHASE1
• Study of an AAV Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma — RECRUITING · PHASE1
• ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors — RECRUITING · PHASE1
• Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors — RECRUITING · PHASE1
• Targeted Pediatric High-Grade Glioma Therapy — RECRUITING
• Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma — RECRUITING · PHASE1
• The EASE Study: Randomized Trial of a Novel Approach to Addressing Fear of Progression in Advanced Cancer — RECRUITING · NA
• Triggered Imaging in Glioblastoma Based on Clinical Outcome Evaluation Compared to Routine: a Feasibility Study — RECRUITING · NA
• Assessment of Early Post-operative Nuclear Imaging in Neurosurgery: a Safety and Feasibility Study in Patients Operated for Glioblastoma — RECRUITING · NA
• Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). — RECRUITING · PHASE1
• Personalized Targeted Glioblastoma Therapies by ex Vivo Drug Screening: Advanced Brain Tumor TheRApy Clinical Trial In Patients Scheduled for shOrt Course radiatioN — RECRUITING · NA
• Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM — RECRUITING · PHASE3

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