Glioma, Malignant Clinical Trials

75 clinical trials for Glioma, Malignant across international registries, including 20 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma — RECRUITING · PHASE1
Imaging of Solid Tumors Using 18F-TRX — RECRUITING · PHASE1
Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma — RECRUITING · PHASE1
Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma — RECRUITING · NA
Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM) — RECRUITING · NA
PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial — RECRUITING · NA
Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM — RECRUITING · PHASE3
Window of Opportunity Study of DSP-0390 in Gliomas — RECRUITING · PHASE1
Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG — RECRUITING · PHASE1
Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss — RECRUITING · PHASE1
CUE-102 in Recurrent Glioblastoma — RECRUITING · PHASE1
Efficacy of a Mixed Distancial Neuropsychological Rehabilitation Program in Patients With Grade 2 or 3 Diffuse Glioma — RECRUITING · NA
18F-Fluciclovine PET-MRI in High-grade Glioma — RECRUITING · PHASE1
Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma — RECRUITING · PHASE1
Concurrent Fluorescence and Sonographically Guided Eradication of Contrast-enhancing Gliomas and Metastases — RECRUITING · NA
FET PET in Differentiating Tumour Progression From Pseudoprogression in High Grade Glioma — RECRUITING · PHASE2
Personalized Rendering of Motor System Functional Plasticity Potential to Improve Glioma Resection and Quality of Life — RECRUITING · NA
Monitoring of Patients With Diffuse Gliomas Using Circulating miRNAs — RECRUITING
A PHASE II, OPEN-LABELED, MULTI-CENTER, RANDOMIZED CONTROLLED TRIAL OF VINBLASTINE +/- BEVACIZUMAB FOR THE TREATMENT OF CHEMOTHERAPY-NAÏVE CHILDREN WITH UNRESECTABLE OR PROGRESSIVE LOW GRADE GLIOMA (LGG) — RECRUITING · PHASE2
PHASE III INTERGROUP STUDY OF TEMOZOLOMIDE ALONE VERSUS RADIOTHERAPY WITH CONCOMITANT AND ADJUVANT TEMOZOLOMIDE VERSUS RADIOTHERAPY WITH ADJUVANT PCV CHEMOTHERAPY IN PATIENTS WITH 1P/19Q CO-DELETED ANAPLASTIC GLIOMA OR LOW GRADE GLIOMA — RECRUITING · PHASE3
Niraparib In Recurrent IDH 1/2 Gliomas — ACTIVE_NOT_RECRUITING · PHASE1
Nimotuzumab Combined With the Stupp Regimen for Postoperative Residual Glioblastoma — NOT_YET_RECRUITING · PHASE2
Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma — SUSPENDED · PHASE1
GRETeL: Tumor Response to Standard Radiotherapy and TMZ Patients With GBM — SUSPENDED
Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM) — SUSPENDED · PHASE1
Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG — TERMINATED · PHASE1
ETAPA I: Peptide-based Tumor Associated Antigen Vaccine in GBM — ACTIVE_NOT_RECRUITING · PHASE1
Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption in GBM Patients — COMPLETED
Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant Gliomas — COMPLETED · NA
AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients — ACTIVE_NOT_RECRUITING · PHASE1
Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma — ACTIVE_NOT_RECRUITING · PHASE1
An Integrated Radio-immunological Approach — ACTIVE_NOT_RECRUITING
A Phase I/IIa Study of C5252 in Patients With Intracranial Tumor — NOT_YET_RECRUITING · PHASE1
Prospective Evaluation of AI R&D Tool in Adult Glioma and Other Primary Brain Tumours (PEAR-GLIO) — TERMINATED
18F-FET-PET/MRI vs Standard MRI Alone for Stereotactic RadioTherapy Planning for High Grade Brain Gliomas — OTHER · NA
General Anesthesia Versus Awake Surgery in Resection of Gliomas and Metastases of Motor Areas — SUSPENDED · NA
Integrated Analysis of Therapy Response and Resistence in Embryonal Tumors and Gliomas — NOT_YET_RECRUITING
Modulation of Ciliogenesis in Glioma Stem Cells — COMPLETED · NA
ONC201 in Pediatric H3 K27M Gliomas — TERMINATED · PHASE1
GMCI, Nivolumab, and Radiation Therapy in Treating Patients With Newly Diagnosed High-Grade Gliomas — COMPLETED · PHASE1
Oral AMXT 1501 Dicaprate in Combination With IV DFMO — TERMINATED · PHASE1
Clinical Study on the Safety and Efficacy of TS-2021 in the Treatment of Recurrent Malignant Glioma — OTHER · PHASE1
Niraparib and Temozolomide in Patients Glioblastoma — NOT_YET_RECRUITING · PHASE1
Effect of Perampanel on Peritumoral Hyperexcitability in HGG — COMPLETED · PHASE1
In Vitro Models From Pediatric Brain Tumors — NOT_YET_RECRUITING
SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors — COMPLETED · PHASE1
Glioblastoma and Individualized Therapies — OTHER
Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma Patients — OTHER · NA
Assessing the Effectiveness of 2D Non-Navigated Intraoperative Ultrasound in Glioma Surgery — COMPLETED
Convection-enhanced Delivery of OS2966 for Patients With High-grade Glioma Undergoing a Surgical Resection — TERMINATED · PHASE1

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