Hepatic Impairment Clinical Trials

272 clinical trials for Hepatic Impairment across international registries, including 17 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Normal Hepatic Function and Participants With Hepatic Impairment — RECRUITING · PHASE1
• A Study to Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems — RECRUITING · PHASE1
• A Study to Evaluate the Effect of Moderate or Severe Hepatic Impairment on the Pharmacokinetics (PK) of Inavolisib — RECRUITING · PHASE1
• A Phase I Study to Investigate the Effect of Hepatic Impairment of AZD9550 and AZD6234 — RECRUITING · PHASE1
• Effect of Hepatic Impairment on the Pharmacokinetics of Mirdametinib — RECRUITING · PHASE1
• Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease — RECRUITING · PHASE1
• A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With and Without Reduced Liver Function — RECRUITING · PHASE1
• A Pharmacokinetic Study of D-2570 in Participants With Hepatic Impairment and Normal Hepatic Function — RECRUITING · PHASE1
• A Study to Assess the Drug Levels and Safety of BMS-986435 in Participants With Normal Hepatic Function and Participants With Different Degrees of Hepatic Impairment — RECRUITING · PHASE1
• A Study to Test How BI 3000202 is Taken up in the Blood of People With and Without Liver Problems — RECRUITING · PHASE1
• Radiprodil in Participants With Hepatic Impairment — RECRUITING · PHASE1
• Assessment of Quizartinib Pharmacokinetic in Subjects With Severe Hepatic Impairment — RECRUITING · PHASE1
• Study to Evaluate the Pharmacokinetics (PK) of E7090 (Herein Referred to as Tasurgratinib) and Its Metabolite in Participants With Mild and Moderate Hepatic Impairment Compared to Healthy Participants — RECRUITING · PHASE1
• Pharmacokinetics (PK) and Safety of Zanzalintinib in Participants With Moderate Hepatic Impairment (HI) — RECRUITING · PHASE1
• Effect of Hepatic Impairment on the Pharmacokinetics and Safety of VIR-2218 and VIR-3434 — RECRUITING · PHASE1
• A Study of HDM1002 in Subjects With And Without Varying Degrees Of Hepatic Impairement — RECRUITING · PHASE1
• A Study of RAY1225 in Participants With Impaired Liver Function — RECRUITING · PHASE1
• Comparative PK Assessment Study of Casdatifan in Moderate Hepatically Impaired Participants Versus Matched Participants With Normal Hepatic Function — NOT_YET_RECRUITING · PHASE1
• A Study of Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015) — ACTIVE_NOT_RECRUITING · PHASE1
• A Study of Calderasib (MK-1084) in Participants With Hepatic Impairment and Healthy Volunteers (MK-1084-017) — COMPLETED · PHASE1
• Study of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With Normal or Severely Impaired Renal or Hepatic Function — COMPLETED · PHASE1
• A Study to Evaluate EDG-7500 in Adults With Hepatic Impairment — COMPLETED · PHASE1
• Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Hepatic Impairment — COMPLETED · PHASE1
• GT-032 Belapectin Hepatic Impairment — COMPLETED · PHASE1
• A Study to Learn How the Study Medicine Called Atirmociclib is Handled by the Body in People With Normal Liver Function and Different Levels of Liver Disease — NOT_YET_RECRUITING · PHASE1
• Pharmacokinetics, Safety and Tolerability of ITF2357 in Participants With Chronic Hepatic Impairment and With Normal Hepatic Function — COMPLETED · PHASE1
• A Clinical Study of Enlicitide Decanoate in People With Liver Function Problems (MK-0616-030) — COMPLETED · PHASE1
• A research study looking into blood levels of the medicine NNC0487 0111 in the body and how well it is tolerated in people with reduced liver function and normal liver function — TERMINATED · PHASE1
• An Investigational Study of ESK-001 in Participants With Normal Liver Function and Participants With Mild, Moderate, and Severe Liver Damage — COMPLETED · PHASE1
• A Phase I Study to Investigate the Effect of Hepatic Impairment on the PK, Safety, and Tolerability of AZD2693 — COMPLETED · PHASE1
• An Open-Label Study Following Oral Dosing of Seladelpar to Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI) — COMPLETED · PHASE1
• A Study of the Blood Levels of Palovarotene in Participants With Abnormal Liver Function Compared to Healthy Adult Participants After Intake of a Single Dose — COMPLETED · PHASE1
• A Study to Investigate the Influence of Hepatic Impairment on Elpipodect (MK-8189) Treatment (MK-8189-012) — COMPLETED · PHASE1
• Pharmacokinetics and Safety of MDR-001 in Mild and Moderate Hepatic Impairment — NOT_YET_RECRUITING · PHASE1
• A Study to Compare the Blood Levels and Safety of Tazemetostat in Participants With Advanced Cancer and Moderate/Severe Liver Impairment to Participants With Advanced Cancer and Normal Liver Function — TERMINATED · PHASE1
• Study of Nalbuphine ER in Participants With Hepatic Impairment — COMPLETED · PHASE1
• A Study About Fazirsiran in People With and Without Liver Problems — COMPLETED · PHASE1
• A Study to Evaluate AMG 133 in Participants With Varying Degrees of Hepatic Impairment or Normal Hepatic Function — COMPLETED · PHASE1
• A Varegacestat Hepatic Impairment Study — COMPLETED · PHASE1
• Phase 1 Study of BPN14770 in Participants With Hepatic Impairment and Healthy Controls — COMPLETED · PHASE1
• A Clinical Study of MK-8527 in Participants With Mild and Moderate Hepatic Impairment (MK-8527-015) — COMPLETED · PHASE1
• A Study to Evaluate Opevesostat (MK-5684) in Male Participants With Moderate Hepatic Impairment (MK-5684-009) — COMPLETED · PHASE1
• A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function — COMPLETED · PHASE1
• Study of Bulevirtide in Participants Who Have Normal or Impaired Liver Function — COMPLETED · PHASE1
• Study to Assess Drug Levels and Safety of Golcadomide (BMS-986369) in Healthy Participants and Participants With Different Degrees of Hepatic Impairment — COMPLETED · PHASE1
• A Clinical Trial of the Study Medicine (Called Fosmanogepix) in Participants With Varying Degrees of Hepatic Function. — COMPLETED · PHASE1
• A Research Study Looking at How a Single Dose of the Medicine Cagrilintide Works in Participants With Reduced Liver Function and in Healthy Participants With Normal Liver Function and How Cagrilintide is Absorbed and Used by the Body — COMPLETED · PHASE1
• A Study to Evaluate the Pharmacokinetics of Divarasib in Healthy Participants and Participants With Impaired Hepatic Function — COMPLETED · PHASE1
• A Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of KP-001 — COMPLETED · PHASE1
• Effect of Hepatic Impairment on M2951 (BTK Inhibitor) PK — COMPLETED · PHASE1

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