Hepatic Insufficiency Clinical Trials

82 clinical trials for Hepatic Insufficiency across international registries, including 4 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Moderate or Severe Hepatic Impairment — RECRUITING · PHASE1
• A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers. — RECRUITING · PHASE1
• Diagnosis of Lymphohistiocytic Hemophagocytosis in Intensive Care — RECRUITING
• A Study of the Pharmacokinetics and Safety of LY3537031 in Participants With Normal Liver Function and With Mild, Moderate, or Severe Liver Impairment — RECRUITING · PHASE1
• Ulonivirine (MK-8507) in Participants With Mild or Moderate Hepatic Impairment (MK-8507-014) — NOT_YET_RECRUITING · PHASE1
• A Study to Investigate Pharmacokinetics (PK) and Safety of a Single Dose of Mavorixafor in Participants With Hepatic Impairment (HI) Compared to Matched Healthy Volunteers With Normal Hepatic Function — COMPLETED · PHASE1
• A Study to Test How BI 1584862 is Taken up in the Blood of People With and Without Liver Problems — COMPLETED · PHASE1
• A Pharmacokinetic and Safety Study of MY008211A Tablets in Subjects With Impaired or Normal Hepatic Function — COMPLETED · PHASE1
• A Clinical Study of Enlicitide Decanoate in People With Liver Function Problems (MK-0616-030) — COMPLETED · PHASE1
• A Study of LY3502970 in Participants With Impaired and Normal Liver Function — COMPLETED · PHASE1
• A Study to Test How Iclepertin is Taken up in the Blood of People With and Without Liver Problems — COMPLETED · PHASE1
• Pharmacokinetics and Safety of MDR-001 in Mild and Moderate Hepatic Impairment — NOT_YET_RECRUITING · PHASE1
• Hepato Biliary Scintigraphy to Assess the Risk of Postoperative Liver Failure Hepatectomies — COMPLETED · NA
• A Study of Bomedemstat (MK-3543) in Participants With Mild or Moderate Hepatic Impairment (MK-3543-023) — COMPLETED · PHASE1
• A Study Evaluating How Moderate Liver Impairment Affects the Absorption, Distribution, Metabolism, and Elimination of Sevabertinib After a Single Oral Dose — COMPLETED · PHASE1
• A Study of the Pharmacokinetics and Safety of Anaprazole Sodium in Special Populations — NOT_YET_RECRUITING · PHASE4
• A Study to Evaluate CC-486/Onureg in Participants With Moderate or Severe Hepatic Impairment Compared With Normal Hepatic Function in Participants With Myeloid Malignancies — TERMINATED · PHASE1
• A Study to Test How BI 1015550 is Taken up in the Blood of People With and Without Liver Problems — COMPLETED · PHASE1
• A Study of Imlunestrant (LY3484356) in Female Participants With Impaired Liver Function — COMPLETED · PHASE1
• A Study of Olomorasib (LY3537982) in Participants With Hepatic Impairment and Healthy Participants — COMPLETED · PHASE1
• A Study of LY3437943 in Participants With Impaired and Normal Liver Function — COMPLETED · PHASE1
• Study to Determine the Pharmacokinetics on TPV/r in Subjects With Mild and Moderate Hepatic Insufficiency — COMPLETED · PHASE1
• Pharmacokinetics (PK) of Tipranavir/Ritonavir, Ribavirin, Pegylated Interferon (Peg INF) in Hepatitis C (HCV) Subjects With Mild Hepatic Impairment and in HCV, Hepatitis B (HBV), Hepatitis D Infected Subjects or Alcoholic Cirrhosis With Moderate Hepatic Impairment — COMPLETED · PHASE1
• Study of Pirtobrutinib (LOXO-305) in Participants With Impaired Liver Function and Healthy Participants — COMPLETED · PHASE1
• A Pharmacokinetic Study of Simufilam in Subjects With Impaired Hepatic Function — COMPLETED · PHASE1
• Clinical Trial of FCN-437c Capsule in Patients With Hepatic Insufficiency — COMPLETED · PHASE1
• A Study to Investigate the Effect of Impaired Hepatic Function on the Pharmacokinetics of Entrectinib in Volunteers With Different Levels of Hepatic Function — COMPLETED · PHASE1
• Pharmacokinetics Of Jaktinib In Subjects With Hepatic Impairment And Normal Hepatic Function — COMPLETED · PHASE1
• Phase 1 Hepatic Insufficiency Trial of Methoxyethyl Etomidate Hydrochloride — OTHER · PHASE1
• A Pharmacokinetic Study to Assess Nevirapine [Viramune] Levels in HIV Infected Patients With Impaired Hepatic Functions — COMPLETED · PHASE4
• Collection of Data of Ceftobiprole Treated Patients: Comparison of Patients With and Without Certain Diseases — COMPLETED
• A Study of Tirzepatide in Participants With Impaired Liver Function — COMPLETED · PHASE1
• Mitochondrial Function in Patients With Severe Liver Disease — TERMINATED · NA
• A Study of LY2140023 in Hepatically-Impaired Participants — COMPLETED · PHASE1
• Investigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its Metabolite — COMPLETED · PHASE1
• A Study to Test How Different Doses of BI 685509 Are Tolerated in Patients With Liver Problems — COMPLETED · PHASE1
• A Study to Evaluate the Effect of Hepatic Insufficiency on the Pharmacokinetics (PK) of ACP-196 — COMPLETED · PHASE1
• Pharmacokinetics of Everolimus in Subjects With Hepatic Insufficiency — COMPLETED · PHASE1
• Study of the Safety and Tolerability of AXA1665 in Subjects With Mild and Moderate Hepatic Insufficiency — COMPLETED · NA
• Pharmacogenetics Sampling of the CC-90007-CP-003 Study Cohort — COMPLETED
• Major Liver Resection: Early Clotting Disorders and Functional Impairment. — COMPLETED
• A Study of Ipatasertib in Participants With Mild, Moderate or Severe Hepatic Impairment Compared to Healthy Participants — COMPLETED · PHASE1
• Single-Dose Pharmacokinetics of MK-3866 in Participants With Hepatic Impairment (MK-3866-006) — TERMINATED · PHASE1
• A Study of Abemaciclib in Participants With Varying Degrees of Liver Impairment — COMPLETED · PHASE1
• Effect of Hepatic and Renal Impairment on the Pharmacokinetics, Safety and Tolerability of BAY1841788 (ODM-201) — COMPLETED · PHASE1
• The Influence of Hepatic Insufficiency on the Pharmacokinetics of Elbasvir (MK-8742) (MK-8742-009) — COMPLETED · PHASE1
• A Single Dose Study of LY2605541 in Participants With Liver Impairment — COMPLETED · PHASE1
• A Study of Evacetrapib (LY2484595) in Participants With Hepatic (Liver) Impairment — COMPLETED · PHASE1
• Clinical Pharmacology of FYU-981 (Subjects With Hepatic Insufficiency) — COMPLETED · PHASE1
• Pharmacokinetics of Suvorexant in Participants With Hepatic Insufficiency (MK-4305-017) — COMPLETED · PHASE1

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