Hereditary Spastic Paraplegia Clinical Trials

38 clinical trials for Hereditary Spastic Paraplegia across international registries, including 18 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• DESCRIBE - DZNE - clinical registry study of neurodegenerative disorders — RECRUITING
• 12-Week Strength and Functional Exercise Program for Hereditary Spastic Paraplegia Trial (HSPMOVE) — RECRUITING · NA
• Neuromodulation to Enhance Motor Function in HSP — RECRUITING · NA
• STOP-HSP.Net: a Registry for Hereditary Spastic Paraplegia as an Integration Tool for Future Therapeutic Strategies — RECRUITING
• Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq) — RECRUITING
• Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia — RECRUITING
• Spastic Paraplegia - Centers of Excellence Research Network — RECRUITING
• Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease — RECRUITING · NA
• Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology — RECRUITING · NA
• Robot-assisted Walking Treatment in Hereditary Spastic Paraplegia (HSP) — RECRUITING
• A Prospective Cohort Study of Surgical Treatment for Foot Deformities in HSP — RECRUITING
• Natural History Study of Patients with HPDL Mutations — RECRUITING
• A Prospective Cohort Study of ITB Treatment for HSP — RECRUITING
• Flexibility, Resistance, Aerobic, Movement Execution Training in Adults With Hereditary Spastic Paraplegia — RECRUITING · NA
• Calcium Folinate Treatment of Spastic Paraplegia 56 — RECRUITING · PHASE1
• The preSPG4 Study - Studying the Prodromal and Early Phase of SPG4 — RECRUITING · NA
• Phenotypes, Biomarkers and Pathophysiology in Hereditary Spastic Paraplegias and Related Disorders — RECRUITING
• Collection of cerebrospinal fluid and performing skin biopsies for obtaining fibroblasts for studies at the DZNE — RECRUITING
• Phenotype, Genotype & Biomarkers in ALS and Related Disorders — ACTIVE_NOT_RECRUITING
• Phenotype, Genotype and Biomarkers 2 — ACTIVE_NOT_RECRUITING
• Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals — COMPLETED · PHASE1
• Efficacy of the Exopulse Mollii Suit on spasticity, mobility, and pain in patients with hereditary spastic paraplegia (HSP): a double-blind, placebo-controlled crossover pilot study. — NOT_YET_RECRUITING
• D-Cycloserine for Serine Palmitoyltransferase Inhibition — COMPLETED · PHASE4
• Clinical and molecular investigations into PGAP1-CDG — OTHER
• Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) — NOT_YET_RECRUITING · PHASE1
• Assessment of the Psychophysical State During Rehabilitation Treatment With Lokomat — COMPLETED
• A Pilot Study of Shockwave Therapy in HSP — WITHDRAWN · NA
• Identification of Modifying Factors in Hereditary Spastic Paraplegia — COMPLETED
• Effect of Dalfampridine in Patients With Hereditary Spastic Paraplegia — COMPLETED · NA
• Trehalose Administration in Subjects With Spastic Paraplegia 11 (3AL-SPG11) — COMPLETED
• Improving Gait Adaptability in Hereditary Spastic Paraplegia — COMPLETED · NA
• Repetitive Transcranial Magnetic Stimulation as Therapy in Hereditary Spastic Paraplegia and Adrenomyeloneuropathy — COMPLETED · NA
• Disease Natural History and Biomarkers of SPG3A, SPG4A, and SPG31 — TERMINATED
• Studying Cognition in SPG4 — COMPLETED
• A Patient Centric Motor Neuron Disease Activities of Daily Living Scale — COMPLETED
• Physiotherapy in Hereditary Spastic Paraplegia — COMPLETED · PHASE2
• Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic Paraplegia — COMPLETED · PHASE2
• Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis — COMPLETED

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