High Grade Glioma Clinical Trials

148 clinical trials for High Grade Glioma across international registries, including 47 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors — RECRUITING · PHASE1
• Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression — RECRUITING · PHASE1
• Atovaquone Combined With Radiation in Children With Malignant Brain Tumors — RECRUITING · PHASE1
• C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B) — RECRUITING · PHASE1
• Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma — RECRUITING · PHASE1
• Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors — RECRUITING · PHASE1
• A Clinical Trial Evaluating the Tolerability, Safety, and Preliminary Efficacy of NRG-103 Injection in Patients With Recurrent or Progressive High-grade Glioma — RECRUITING · PHASE1
• Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases — RECRUITING · PHASE3
• MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas — RECRUITING · PHASE1
• Dabrafenib and/or Trametinib Rollover Study — RECRUITING · PHASE4
• Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG) — RECRUITING · PHASE1
• Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion — RECRUITING · PHASE1
• STARLITE for Unresectable High-Grade Gliomas — RECRUITING · PHASE1
• A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) — RECRUITING · PHASE1
• Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021) — RECRUITING · PHASE1
• Study of Olutasidenib and Temozolomide in HGG — RECRUITING · PHASE2
• Targeted Pediatric High-Grade Glioma Therapy — RECRUITING
• Multiparametic Metabolic and Hypoxic PET/MRI for Disease Assessment in High Grade Glioma — RECRUITING · PHASE1
• Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma — RECRUITING · NA
• Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM) — RECRUITING · NA
• Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant — RECRUITING · PHASE2
• DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma — RECRUITING · PHASE2
• Intratumoral DNX-2401 for High Grade Pediatric Brain Tumors — RECRUITING · PHASE2
• Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors — RECRUITING · PHASE2
• PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma — RECRUITING · PHASE2
• Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) In Newly Diagnosed Glioma (WHO G3-G4) — RECRUITING · NA
• Safety and Efficacy Study of TX103 CAR-T Cell Therapy for Recurrent or Progressive Grade 4 Glioma. — RECRUITING · PHASE1
• MRI in High-Grade Glioma Patients Undergoing Chemoradiation — RECRUITING · NA
• Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma — RECRUITING · PHASE1
• A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion — RECRUITING · PHASE1
• DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma — RECRUITING · PHASE1
• A Living Tissue Bank of Patient-Derived Organoids From Glioma Tumors — RECRUITING
• Concurrent XRD-0394 With Radiation Therapy for High Grade Gliomas — RECRUITING · PHASE1
• Fluorescence Enhanced Stereotactic Surgery (FESS) — RECRUITING
• 18F-Fluciclovine PET-MRI in High-grade Glioma — RECRUITING · PHASE1
• Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors — RECRUITING · PHASE1
• A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions — RECRUITING · PHASE1
• A Pilot Study Investigating Upfront Adaptive Immunotherapy Approach in Children, Adolescent and Young Adult (CAYA) Patients With Replication-Repair Deficient (RRD) High-Grade Gliomas (HGG) — RECRUITING · NA
• Multi-Dimensional MRI Spatial Heterogeneity Analysis for Predicting Key Genes and Prognosis of High-Grade Gliomas: A Multi-Center Study — RECRUITING
• Phase 1 Study of Locoregional Injections of Ex Vivo Expanded Natural Killer Cells — RECRUITING · PHASE1
• A Study of Chlorophyllin for the Management of Brain Radio-necrosis in Patients With Diffuse Glioma — RECRUITING · PHASE2
• Injection of Active Allogeneic Natural Killer Cells in Patients With Gliomas — RECRUITING · PHASE2
• Clinical Study of Carbon Ion Radiotherapy for High-grade Glioma — RECRUITING · NA
• GD2-CAR T Cells for Pediatric Brain Tumours — RECRUITING · PHASE1
• Surgical Suction Aspirates Fluorescence Measurement — RECRUITING
• A Novel Target Delineation Scheme in High-grade Glioma Patients: a Randomized Single-blind Clinical Trial — RECRUITING · NA
• The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201) — RECRUITING
• Treatment with bevacizumab and irinotecan in patients with recurrent or refractory high grade glioma after conventional treatment. — COMPLETED · PHASE2
• A randomised phase 2 trial investigating the additional benefit of hydroxychloroquine (HCQ) to short course radiotherapy (SCRT) in patients aged 70 years and older with high grade gliomas (HGG) — TERMINATED · PHASE2
• Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy — SUSPENDED · PHASE2

Refine this search