Huntington Disease Clinical Trials

229 clinical trials for Huntington Disease across international registries, including 44 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease — RECRUITING · PHASE3
• Pridopidine Phase 3 Study in Huntington's Disease — RECRUITING · PHASE3
• Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease — RECRUITING · PHASE2
• A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease — RECRUITING · PHASE1
• Optimizing Parameters of Low-Intensity Focused Ultrasound for Pallidal Modulation in Huntington's Disease — RECRUITING · NA
• Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders — RECRUITING
• Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease — RECRUITING · PHASE1
• iMagemHTT-009- FIH Evaluation of Novel Mutant Huntingtin PET Radioligand [11C]CHDI-00491009 — RECRUITING · PHASE1
• Evaluation of Three Tests to Assess Social Cognition in Huntington Disease — RECRUITING
• Cognitive Assessment Tools for Huntington's Disease. — RECRUITING
• Study of BDNF Pathway Biomarkers in the Cerebrospinal Fluid in Patients With Huntington's Disease — RECRUITING · NA
• Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's Disease — RECRUITING · NA
• Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease — RECRUITING · NA
• Retinal Imaging in Neurodegenerative Disease — RECRUITING
• A RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND PHASE 3 STUDY TO EVALUATE THE EFFICACY, SAFETY AND TOLERABILITY OF VOTOPLAM IN PARTICIPANTS WITH HUNTINGTON’S DISEASE — RECRUITING · PHASE3
• Hinting Task for Huntington's Disease — RECRUITING
• Digital Measures for Clinical Trial Endpoints in Huntington's Disease — RECRUITING
• Frequency of selected single nucleotide polymorphisms in phase with the mutant and wild-type HTT alleles in huntington disease gene expansion carriers — RECRUITING
• Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD) — RECRUITING · NA
• A PHASE I, 2-PART STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF SINGLE ASCENDING DOSES OF INTRATHECALLY ADMINISTERED RG6496 IN A RANDOMIZED, PLACEBO-CONTROLLED, INVESTIGATOR/PARTICIPANT-BLIND STUDY WITH AN OPEN-LABEL EXTENSION IN HUNTINGTON'S DISEASE GENE EXPANSION CARRIERS — RECRUITING · PHASE1
• Longitudinal Endpoint Assessment of Disease Burden in HD — RECRUITING
• A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD — RECRUITING · PHASE1
• Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology — RECRUITING · NA
• Comparison Between [11C]UCB-J and [18F]SynVest-1 PET in HD. — RECRUITING · NA
• Gut Microbiomes in HD — RECRUITING
• Huntington's Disease Biobank: Advancing Remote Monitoring and Deep Phenotyping — RECRUITING
• The NAD-HD Study: A Study to Investigate Efficacy and Safety of Nicotinamide Riboside Compared With Placebo in Huntington's Disease — RECRUITING · PHASE2
• IMarkHD: in Vivo Longitudinal Imaging of HD Pathology — RECRUITING
• NYSCF Scientific Discovery Biobank — RECRUITING
• A Randomised Controlled Trial, Of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion Carriers — RECRUITING · PHASE2
• Trial of the Combined Use of Thiamine and Biotin in Patients With Huntington's Disease — RECRUITING · PHASE2
• Clinical observational study on the relationship between digital and clinical parameters of fatigue and sleep disturbances in neurodegenerative disorders and immune-mediated inflammatory diseases — RECRUITING
• Early Biomarkers in Premanifest Huntington's Disease Gene Carriers: a Pilot Study — RECRUITING · NA
• Extracellular Vesicles for HD — RECRUITING
• FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases — RECRUITING
• A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY, TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF INTRATHECALLY ADMINISTERED SINGLE ASCENDING DOSES OF ALN-HTT02 IN ADULT PATIENTS WITH HUNTINGTON'S DISEASE — RECRUITING
• A PHASE 2B, DOUBLE-BLIND, RANDOMIZED EXTENSION STUDY TO EVALUATE THE LONG-TERM SAFETY AND EFFICACY OF VOTOPLAM IN PARTICIPANTS WITH HUNTINGTON'S DISEASE — RECRUITING · PHASE2
• Innovative Imaging and Cognitive BIOmarkers to Predict Huntington's Disease Progression — RECRUITING · NA
• LONG-TERM STUDY TO EVALUATE SAFETY AND TOLERABILITY OF VALBENAZINE IN PATIENTS WITH CHOREA ASSOCIATED WITH HUNTINGTON DISEASE IN CANADA — RECRUITING
• A PHASE II, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-FINDING STUDY TO INVESTIGATE THE SAFETY, BIOMARKERS, AND EFFICACY OF TOMINERSEN IN INDIVIDUALS WITH PRODROMAL AND EARLY MANIFEST HUNTINGTON'S DISEASE — RECRUITING · PHASE2
• Register study on neuroprognostics in patients with neurological / neurosurgical diseases in intensive care unit — RECRUITING
• HDClarity: a multi-site cerebrospinal fluid collection initiative to facilitate therapeutic development for Huntington’s disease — RECRUITING
• A PHASE 2, MULTI-CENTER, DOUBLE-BLIND, PLACEBO CONTROLLED STUDY IN SUBJECTS WITH LATE PRODROMAL AND EARLY MANIFEST HUNTINGTON DISEASE (HD) TO ASSESS THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF VX15/2503 — RECRUITING · PHASE2
• A RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED STUDY OF SD-809 EXTENDED RELEASE FOR THE TREATMENT OF CHOREA ASSOCIATED WITH HUNTINGTON DISEASE — RECRUITING
• GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's Disease — ACTIVE_NOT_RECRUITING · PHASE2
• Gene Therapy Development and Validation for Huntington's Disease Fibro TG-HD — COMPLETED · NA
• Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register Study — ACTIVE_NOT_RECRUITING
• Impact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington Disease — ACTIVE_NOT_RECRUITING · PHASE2
• Proof of Concept of an Anaplerotic Study Using Brain Phosphorus Magnetic Resonance Spectroscopy in Huntington Disease — COMPLETED · PHASE2
• Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers — COMPLETED

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