Hypercholesterolaemia Clinical Trials

48 clinical trials for Hypercholesterolaemia across international registries, including 6 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia — RECRUITING · PHASE2
• A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias — RECRUITING · PHASE1
• An Efficacy and Safety Study of Akkermansia Muciniphila AKM Lab-01 in Hypercholesterolaemia — RECRUITING · NA
• Phase 3 Clinical Study Evaluating Efficacy, Safety, and Tolerability of Obicetrapib Vs Bempedoic Acid to Treat Dyslipidemia in Adults With Primary Non-familial Hypercholesterolemia or Mixed Dyslipidemia at High to Very High Cardiovascular Risk, During a Treatment Period of Approximately 84 Days — RECRUITING · PHASE3
• Evaluation of Adherence, Persistence and Efficacy of Treatment With Alirocumab 300mg in Italy — RECRUITING
• LATAM LOWERS LDL-C — RECRUITING · PHASE4
• Efficacy and Safety of SAR236553 (REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients with Heterozygous Familial Hypercholesterolemia — COMPLETED · PHASE3
• Study to assess the tolerability and efficacy of AMG 145 in patients with hypercholesterolemia unable to tolerate an effective dose of a statin. — COMPLETED · PHASE2
• Effect of Tredaptive on serum lipoproteins, lipoproteins metabolism, oxidative stress and HDL antioxidant function. — COMPLETED · PHASE4
• An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents with Heterozygous Familial Hypercholesterolemia — COMPLETED · PHASE2
• A phase IV, 6-week, randomised, double-blind, multicentre, parallel group, comparative study to evaluate the efficacy of rosuvastatin 5 mg and atorvastatin 10 mg in UK Asian subjects with primary hypercholesterolaemia — TERMINATED · PHASE4
• Specified Drug-use Survey of Leqvio for s.c. Injection. — ACTIVE_NOT_RECRUITING
• A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Laroprovstat, Rosuvastatin and Placebo on LDL-C in LLT-naïve Patients. — NOT_YET_RECRUITING · PHASE3
• A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Rosuvastatin on LDL-C in Patients With Hypercholesterolaemia — NOT_YET_RECRUITING · PHASE3
• An Observational Study to Evaluate Treatment Patterns in High, Very High and Extreme Cardiovascular Risk Patients With Hypercholesterolemia, Including Familial Hypercholesterolemia — NOT_YET_RECRUITING
• Impact of Phytosterol-Rich Extract on Lipid Profile — COMPLETED · NA
• Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes — ACTIVE_NOT_RECRUITING · PHASE3
• Efficacy of Lactobacillus Mucosae DPC6426 on Blood-lipids — COMPLETED · NA
• A clinical trial of MK-3214 taken with different liquids in healthy participants (MK-3214-002) — OTHER · PHASE1
• Bioequivalence Study of Bempedoic Acid 180 mg Film Coated Tablet and Nilemdo® (Bempedoic Acid) 180 mg Film-coated Tablets — COMPLETED · PHASE1
• Treatment With Rosuvastatin Versus Switching PI (Protease Inhibitor) in Patients HIV With High Cholesterol Levels — COMPLETED · PHASE4
• Single Dose Oral Bioequivalence Study of Bempedoic Acid 180 mg Film Coated Tablet and Nilemdo® (Bempedoic Acid) 180 mg Film-coated Tablets in Healthy Adult Human Subjects Under Fasting Conditions. — COMPLETED · PHASE1
• A clinical study of MK-3214 in healthy people (MK-3214-001) — OTHER · PHASE1
• A Study of PCSK9 Inhibitor AK102 in Healthy Subjects — COMPLETED · PHASE1
• Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Renal Impairment Study (MK-0616-020) — COMPLETED · PHASE1
• TWICE (Ezetimibe Together With Any Statin Cholesterol Enhancement)(0653-060) — COMPLETED · PHASE3
• Ezetimibe Plus Simvastatin Versus Simvastatin in Untreated Subjects With High Cholesterol (P03435) — COMPLETED · PHASE4
• Chart Review of Repatha® in Subjects With Hyperlipidaemia — COMPLETED
• An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia — COMPLETED · PHASE3
• A Research Study Investigating How NNC0385-0434 is Tolerated in People With or Without High Cholesterol Levels — COMPLETED · PHASE1
• Carotid Atorvastatin Study in Hyperlipidemic Post-Menopausal Women — COMPLETED · PHASE3
• Study to Evaluate the Safety of Repatha® in Pregnancy — TERMINATED
• Pharmacokinetic Drug Interaction Study Between Raltegravir and Atorvastatin. — COMPLETED · PHASE1
• Usability Study of the Commercial Auto-injector Device and the New Auto-injector Device (SYDNEY) in Patients With High or Very High CV Risk With Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy — COMPLETED · PHASE3
• An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia — COMPLETED · PHASE2
• Efficacy and Safety of Alirocumab Versus Placebo on Top of Maximally Tolerated Lipid Lowering Therapy in Patients With Hypercholesterolemia Who Have Type 1 or Type 2 Diabetes and Are Treated With Insulin (ODYSSEY DM - Insulin) — COMPLETED · PHASE3
• Acotral® Versus Zetia® Ezetimibe Bioequivalance Study. — COMPLETED · PHASE1
• Rosuvastatin Calcium Bioequivalence Study - Fast — COMPLETED · PHASE1
• Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia (ODYSSEY HIGH FH) — COMPLETED · PHASE3
• The Effect of a Red Rice and Olive Extract Nutrition Supplement on Cholesterol Levels in Patients With Metabolic Syndrome — COMPLETED · PHASE4
• Evaluation of Patients Treated With HMG-CoA Reductase Inhibitors to Reach Cholesterol Target Values — COMPLETED
• Dose Effect of Limicol on (LDL)-Cholesterol Levels — COMPLETED · NA
• Non-interventional Study (NIS) to Assess Reaching of Cholesterol Target Values in Patients Treated With HMG-CoA Reductase Inhibitors — COMPLETED
• Registry On Efficacy and Safety Of Rosuvastatin, and Atorvastatin and Simvastatin In Hypercholesterolaemia — COMPLETED
• Study of Asian Patients With Hypercholesterolaemia in the UK - Rosuvastatin 5mg Versus Atorvastatin 10mg — TERMINATED · PHASE4
• Rosuvastatin Efficacy and Safety Evaluation in Hypercholesterolaemic Patients — COMPLETED
• PULSAR - A Prospective Study to Evaluate the Utility of Low Doses of the Statins Atorvastatin and Rosuvastatin. — COMPLETED · PHASE3
• OLE Study to Evaluate Safety / Efficacy of ZD4522 — COMPLETED · PHASE3

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