Hyperoxaluria Clinical Trials

27 clinical trials for Hyperoxaluria across international registries, including 4 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Prospective Research Rare Kidney Stones (ProRKS) — RECRUITING
• PHASE 1-2A SAFETY, TOLERABILITY, AND PHARMACODYNAMICS CONTROLLED STUDY OF NOV-001 IN HEALTHY VOLUNTEERS AND PATIENTS WITH ENTERIC HYPEROXALURIA — RECRUITING · PHASE1
• EVALUATE THE SAFETY AND EFFICACY OF RELOXALIASE (OXALATE DECARBOXYLASE) IN PATIENTS WITH ENTERIC HYPEROXALURIA: A PHASE III RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY (URIROX-2) — RECRUITING · PHASE3
• AN OPEN-LABEL ROLL-OVER STUDY TO EVALUATE THE LONG-TERM SAFETY AND EFFICACY OF DCR-PHXC SOLUTION FOR INJECTION (SUBCUTANEOUS USE) IN PATIENTS WITH PRIMARY HYPEROXALURIA — RECRUITING
• Validation Testing for Plasma Oxalate Levels in the Biochemical Laboratory at the Galilee Medical Center, in Collaboration With the Biochemistry Laboratory at CHARITE Hospital in Berlin, and Testing the Relationship Between Oxalate Levels and Vitamin C Levels in Plasma — NOT_YET_RECRUITING
• Oxalate Excretion Profile in Patients With a Heterozygous Mutation of the AGXT (Alanine-glyoxylate Aminotransferase) Gene — COMPLETED · NA
• A Novel Approach for Reducing Hyperoxaluria and Kidney Stone Risk. — COMPLETED · PHASE4
• A Study of BMN 255 in Participants With Non-Alcoholic Fatty Liver Disease And Hyperoxaluria — WITHDRAWN · PHASE1
• Dapagliflozin and Hydrochlorothiazide in Recurring Kidney Stone Patients — OTHER · PHASE4
• Plasma Oxalate in Patient With Short Bowel — COMPLETED
• A Pilot Study of Oxalate Absorption in Secondary Hyperoxaluria — COMPLETED · NA
• A PHASE 2 OPEN-LABEL MULTICENTER STUDY TO EVALUATE THE SAFETY, PHARMACOKINETICS, AND EFFICACY OF NEDOSIRAN IN PEDIATRIC PATIENTS FROM BIRTH TO 5 YEARS OF AGE WITH PRIMARY HYPEROXALURIA AND RELATIVELY INTACT RENAL FUNCTION — NOT_YET_RECRUITING · PHASE2
• Reference Interval of Spot Urinary Oxalate to Creatinine Ratio in Children — COMPLETED
• Spot Urine Oxalate to Creatinine Ratio and 24 Hours Urinary Oxalate — COMPLETED
• Enteric Oxalate Absorption Study in Unclassified Hyperoxaluria — COMPLETED · PHASE1
• Evaluating ALLN-177 for Reducing Urinary Oxalate Excretion in Calcium Oxalate Kidney Stone Formers With Hyperoxaluria — COMPLETED · PHASE2
• A PHASE 2 PLACEBO-CONTROLLED, DOUBLE-BLIND, MULTICENTER STUDY TO EVALUATE THE EFFICACY, SAFETY, AND TOLERABILITY OF DCR-PHXC SOLUTION FOR INJECTION (SUBCUTANEOUS USE) IN PATIENTS WITH PRIMARY HYPEROXALURIA (PLACEBO CONTROLLED) — COMPLETED · PHASE2
• A PHASE III DOUBLE-BLIND, RANDOMISED STUDY TO EVALUATE THE LONG-TERM EFFICACY AND SAFETY OF OXABACT IN PATIENTS WITH PRIMARY HYPEROXALURIA — NOT_YET_RECRUITING · PHASE3
• Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Hyperoxaluria and Kidney Stones — COMPLETED · PHASE2
• Hydroxyproline Influence on Oxalate Metabolism — COMPLETED · PHASE1
• Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Secondary Hyperoxaluria and Kidney Stones Over 28 Days — COMPLETED · PHASE2
• Effect of Over-the-counter Dietary Supplements on Kidney Stone Risk — COMPLETED · NA
• Renal Protective Effect of ACEI and ARB in Primary Hyperoxaluria — WITHDRAWN · PHASE3
• Efficacy of Betaine for Reduction of Urine Oxalate in Patients With Type 1 Primary Hyperoxaluria — COMPLETED · PHASE2
• Oxazyme in Patients With Hyperoxaluria — COMPLETED · PHASE1
• Use of Oral Probiotics to Reduce Urinary Oxalate Excretion — COMPLETED · PHASE1
• Proteomic Study of Urinary Stone Disease — COMPLETED

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