Immune System Diseases Clinical Trials

115 clinical trials for Immune System Diseases across international registries, including 12 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia — RECRUITING
• Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies — RECRUITING · PHASE2
• Long-term extension study to evaluate the safety and efficacy of riliprubart (SAR445088) in participants with chronic inflammatory demyelinating polyneuropathy (CIDP) — RECRUITING · PHASE3
• Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES) — RECRUITING
• METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D) — RECRUITING · PHASE2
• A Study of the Safety and Activity of Sparsentan for the Treatment of Patients With Immunoglobulin A Nephropathy — RECRUITING · PHASE2
• A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition — RECRUITING · PHASE2
• Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity — RECRUITING · PHASE2
• A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus — RECRUITING · PHASE1
• Implementation of Support in the Care of Adults Living With Type 1 Diabetes — RECRUITING · NA
• Support-t Online Training in Youth Living With Type 1 Diabetes Transitioning to Adult Care — RECRUITING · NA
• A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study — RECRUITING · PHASE1
• Music-4-MS to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study — NOT_YET_RECRUITING · NA
• Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma — ACTIVE_NOT_RECRUITING · PHASE1
• Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma — ACTIVE_NOT_RECRUITING · PHASE2
• An open-label Phase 2 study to investigate the efficacy and safety of rilzabrutinib in adult participants with Graves’ disease — TERMINATED · PHASE2
• A Multicenter, Multinational, Randomized, Double-blind, Placebo-Controlled, Phase 3 Maintenance Study to Evaluate the Efficacy and Safety of Duvakitug in Participants with Moderately to Severely Active Ulcerative Colitis — TERMINATED · PHASE3
• A multicenter, multinational, randomized, double-blind, placebo-controlled Phase 3, maintenance study to evaluate the efficacy and safety of duvakitug in participants with moderately to severely active Crohn’s disease — TERMINATED · PHASE3
• HIV Engagement and Adolescent Depression Support (HEADS-UP) — COMPLETED · NA
• A multicenter, multinational, randomized, double-blind, placebo-controlled Phase 3, induction study to evaluate the efficacy and safety of duvakitug in participants with moderately to severely active Ulcerative Colitis. — TERMINATED · PHASE3
• Immuno-Oncology Database and Bioregistry — COMPLETED
• A parallel-group treatment, Phase 2a, multicenter, randomized, double-blind, placebo-controlled umbrella study to evaluate the efficacy and safety of frexalimab, brivekimig and rilzabrutinib in participants aged 16 to 75 years with primary focal segmental glomerulosclerosis (FSGS) or minimal change disease (MCD) — TERMINATED · PHASE2
• Study of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL — ACTIVE_NOT_RECRUITING · PHASE1
• Abrocitinib Taiwan Treatment Pattern and Real World Study in ATopiC Dermatitis (ATTRACT Registry) — ACTIVE_NOT_RECRUITING
• Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL — ACTIVE_NOT_RECRUITING · PHASE1
• Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL — ACTIVE_NOT_RECRUITING · PHASE1
• Administration of T Lymphocytes for Prevention of Relapse of Lymphomas — ACTIVE_NOT_RECRUITING · PHASE1
• A randomized, Phase 3, double-blind, 52-week study to evaluate the efficacy and safety of rilzabrutinib (SAR444671) compared to placebo in adult participants with active IgG4-related disease — TERMINATED · PHASE3
• An Open-Label, FIH Study Evaluating the Safety, Tolerability, and Efficacy of VCTX211 Combination Product in Subjects With T1D — TERMINATED · PHASE1
• Oral Immunotherapy in Food Allergy in Finland — COMPLETED · NA
• Clonal Hematopoiesis of Immunological Significance — NOT_YET_RECRUITING
• Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation — ACTIVE_NOT_RECRUITING · PHASE2
• A Study of Peresolimab (LY3462817) in Participants With Moderately-to-Severely Active Rheumatoid Arthritis — TERMINATED · PHASE2
• A Safety and Efficacy Study of PVX108 in Children and Adolescents With Peanut Allergy — ACTIVE_NOT_RECRUITING · PHASE2
• Study of ATLCAR.CD138 Cells for Relapsed/Refractory Multiple Myeloma — ACTIVE_NOT_RECRUITING · PHASE1
• The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP) — WITHDRAWN · PHASE1
• Effect of Benralizumab in Atopic Dermatitis — COMPLETED · PHASE2
• A study to investigate how different tablet types of balinatunfib and food will influence the absorption of balinatunfib in blood in healthy adult participants — OTHER · PHASE1
• Group Education Trial to Improve Transition for Parents of Adolescents With T1D — ACTIVE_NOT_RECRUITING · NA
• IDP-023 g-NK Cells Plus Ocrelizumab in Patients With Progressive Multiple Sclerosis — SUSPENDED · PHASE1
• Individualizing Treatment for Asthma in Primary Care — COMPLETED · PHASE4
• A FIRST-IN-HUMAN PHASE I TRIAL OF OX118 IN HEALTHY VOLUNTEERS — OTHER · PHASE1
• Ukulele Playing to Improve Cognition in People with Multiple Sclerosis: a Feasibility Study — COMPLETED · NA
• Mechanism of Action of Ocrelizumab in Multiple Sclerosis — COMPLETED
• A Study of Safety and Drug Levels of HIB210 in Healthy Volunteers — COMPLETED · PHASE1
• Upper Extremity Function in Multiple Sclerosis Patients With Advanced Disability Treated With Ocrevus — COMPLETED
• Friendship Bench Adaptation to Improve Mental Health & HIV Care Engagement Outcomes Among PLWH and PWID in Vietnam — COMPLETED · NA
• Digital Diagnostics and Intervention Services for Parkinson's Disease — NOT_YET_RECRUITING
• Effect of SAR445611 on inflammatory responses following LPS challenge study in healthy participants — OTHER · PHASE1
• Biodiversity Interventions for Well-Being — ACTIVE_NOT_RECRUITING · NA

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