Kidney Transplant Rejection Clinical Trials

102 clinical trials for Kidney Transplant Rejection across international registries, including 19 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Treatment of Antibody-Mediated Rejection (ABMR) With CarBel — RECRUITING · PHASE1
• A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney Transplantation — RECRUITING · PHASE2
• A seamless Phase 2/3 randomized, open-label study to investigate efficacy and safety of frexalimab versus tacrolimus in adult kidney transplant recipients — RECRUITING · PHASE3
• Trifecta-Kidney cfDNA-MMDx Study — RECRUITING
• Treatment of Chronic Active Antibody Mediated Rejection With Tocilizumab — RECRUITING · NA
• Platelet Aggregation in the Diagnosis of Acute Graft Rejection — RECRUITING
• Long-Term Safety and Efficacy of Tegoprubart in Kidney Transplant Recipients — RECRUITING · PHASE2
• Validation of Donor-Derived Cell-Free DNA (Dd-cfDNA) for Kidney Transplant Monitoring — RECRUITING
• Australian Genomics Of Chronic Allograft Dysfunction Study — RECRUITING
• CRISPR-Edited HLA Donor Kidney Transplant to Reduce Rejection Risk — RECRUITING · PHASE1
• Added Value of 18 FDG Pet-scanner in Diagnosis and Management of Subclinical Rejection in Kidney Transplant Patients — RECRUITING · NA
• Fingolimod for the Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation — RECRUITING · PHASE2
• PRObiotics for KIdney Transplantation — RECRUITING · NA
• A DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER, RANDOMIZED PHASE 3 TRIAL EVALUATING THE EFFICACY AND SAFETY OF FELZARTAMAB IN KIDNEY TRANSPLANT RECIPIENTS WITH LATE ANTIBODY-MEDIATED REJECTION (AMR) (TRANSCEND) — RECRUITING · PHASE3
• A PHASE 2, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE EFFICACY AND SAFETY OF ALXN2030 IN ADULT PATIENTS WITH ANTIBODY MEDIATED REJECTION AFTER KIDNEY TRANSPLANTATION — RECRUITING · PHASE2
• Expanding the Scope of Post-transplant HLA-specific Antibody Detection and Monitoring in Renal Transplant Recipients — RECRUITING
• A GLOBAL, MULTICENTER, RANDOMIZED, DOUBLE-BLINDED, PLACEBO-CONTROLLED, PHASE 2 STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND EFFICACY OF EFGARTIGIMOD PH20 SC ADMINISTERED BY A PREFILLED SYRINGE IN KIDNEY TRANSPLANT RECIPIENTS WITH ANTIBODY-MEDIATED REJECTION — RECRUITING · PHASE2
• Multi Center Observation of Sentinel Skin Graft for Detecting Acute Rejection After Renal Transplantation — RECRUITING
• A PIVOTAL PHASE 3 TRIAL TO EVALUATE THE SAFETY AND EFFICACY OF CLAZAKIZUMAB FOR THE TREATMENT OF CHRONIC ACTIVE ANTIBODY MEDIATED REJECTION IN KIDNEY TRANSPLANT RECIPIENTS — RECRUITING · PHASE3
• Microbiome and Immunosuppression: The Mission Study — ACTIVE_NOT_RECRUITING
• Impact of the Microbiota on the Likelihood of Renal Graft Rejection — ACTIVE_NOT_RECRUITING
• Safety and Efficacy of Tegoprubart in Patients Undergoing Kidney Transplantation — COMPLETED · PHASE2
• Evaluating Urinary CXCL10 for Enhanced Detection of Acute Rejection in Kidney Transplant Patients With Low DD-CFDNA — COMPLETED
• Safety & Tolerability Study of Chimeric Antigen Receptor T-Reg Cell Therapy in Living Donor Renal Transplant Recipients — COMPLETED · PHASE1
• Screening for Subclinical Antibody Mediated Rejection and Efficacy of Belatacept in the Context of de Novo Donor Specific Antibody After Kidney Transplantation (BELA-M-R) — NOT_YET_RECRUITING · PHASE2
• Observational Cohort Study Renal Transplantation University Hospitals Leuven — ACTIVE_NOT_RECRUITING
• Immune Monitoring of Prevalent Kidney Transplant Recipients Using Torque Teno Virus: A Single-Center, Prospective Cohort Study — COMPLETED
• The smartNTx Trial:Telemedical Management Versus Standard Aftercare in Kidney Transplant Recipients (KTR) — ACTIVE_NOT_RECRUITING · NA
• Belimumab to Mobilise Memory B-cells From Secondary Lymhoid Organs to Improve Memory B-cell HLA-specificity Profiling to Support Delisting for Transplant Access in Highly-sensitized — NOT_YET_RECRUITING · PHASE2
• Long-Term Follow-Up of Patients Who Have Received An Autologous Antigen-Specific Chimeric Antigen Receptor T Regulatory Cell Therapy (CAR-Treg therapy, TX200-TR101) In A Prior Clinical study — TERMINATED · PHASE3
• Using MSCs for Chronic Active Antibody Mediated Rejection — NOT_YET_RECRUITING · NA
• AIIM Trial: Personalized Medicine Approach to Kidney Allograft Function — NOT_YET_RECRUITING · NA
• Long-Term Follow-Up of TX200-TR101 (STEADFAST Long Term) — ACTIVE_NOT_RECRUITING
• Validation of Genomic Immune-phenotyping Profiles to Predict Risk of Kidney Transplant Rejection — ACTIVE_NOT_RECRUITING
• PIONEER Trial (Post-Transplant Application of TruGraf and TRAC Molecular Panel in Renal Transplant Recipients) — NOT_YET_RECRUITING
• Simplified IMmunosuppressive Protocol Utilizing Low Dose EnvarsusXR — TERMINATED · PHASE4
• PROACT Pilot Trial — ACTIVE_NOT_RECRUITING
• An Long-term Follow-up Trial of Kidney Tx Patients Treated With Imlifidase or PE After an AMR — TERMINATED
• Clazakizumab for Chronic and Active Antibody Mediated Rejection Post-Kidney Transplant — COMPLETED · PHASE1
• Longitudinal Changes in Donor-Derived Cell-Free DNA With Tocilizumab Treatment for Chronic Antibody-Mediated Rejection — ACTIVE_NOT_RECRUITING
• Transplant Antibody-Mediated Rejection: Guiding Effective Treatments — TERMINATED · PHASE3
• Utilising Volumetric Absorptive Microsampling (VAMS) Technology to Monitor Tacrolimus and Creatinine — SUSPENDED
• GEnomic Medicine in Kidney Transplantation Study — NOT_YET_RECRUITING
• Improving KIdney Transplantation with Cellular Therapy Study — TERMINATED
• Autologous Tolerogenic Dendritic Cells (ATDC) for Highly Sensitized Kidney Transplant Recipients — NOT_YET_RECRUITING · PHASE1
• Donor-derived Cell-free DNA for Early Diagnosis of Antibody-mediated Rejection — COMPLETED · NA
• Efficacy of Achieving Early Target Trough Levels of Tacrolimus Using CYP3A5 Guided Dosing Versus Weight-based Dosing in a Multi-ethnic Population of Kidney Transplant Recipients in Singapore — COMPLETED · NA
• Clinical Impact of the IBox As an Early Intervention TooL — ACTIVE_NOT_RECRUITING · NA
• The PROspera Kidney Transplant ACTIVE Rejection Assessment Registry (ProActive) — ACTIVE_NOT_RECRUITING
• Impact of Microvascular Inflammation on Kidney Allograft Outcome — COMPLETED

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