Leber Hereditary Optic Neuropathy Clinical Trials

16 clinical trials for Leber Hereditary Optic Neuropathy across international registries, including 3 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Stem Cell Ophthalmology Treatment Study II — RECRUITING · NA
• New Non-invasive Modalities for Assessing Retinal Structure and Function — RECRUITING · NA
• Metabolomics Analysis According to the Retinal Nerve Fiber Layer in Patients With NOHL Mutations (MétabOCT) — RECRUITING · NA
• Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year — COMPLETED · PHASE3
• Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients — COMPLETED · PHASE1
• RESCUE and REVERSE Long-term Follow-up — COMPLETED · PHASE3
• EAP_GS010_single Patient — TERMINATED
• REALITY LHON Registry — COMPLETED
• A Phase 3, Multicenter, Randomized, Double-Masked, Sham-Controlled Clinical Trial for Leber's Hereditary Optic Neuropathy (LHON) Associated With ND4 Mutation — ACTIVE_NOT_RECRUITING · PHASE3
• Pilot Study of the Efficacy of Nicotinamide (Vitamin B3) in Leber's Hereditary Optic Neuropathy — NOT_YET_RECRUITING · PHASE1
• Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND1 Mutations — TERMINATED · PHASE1
• Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND4 Mutations — ACTIVE_NOT_RECRUITING · PHASE1
• A Single Intravitreal Injection of rAAV2-ND4 for the Treatment of Leber's Hereditary Optic Neuropathy — OTHER · PHASE2
• Safety and Efficacy Study of rAAV2-ND4 Treatment of Leber Hereditary Optic Neuropathy (LHON) — COMPLETED · NA
• Trial of Cyclosporine in the Acute Phase of Leber Hereditary Optic Neuropathy — OTHER · PHASE2
• Leber Hereditary Optic Neuropathy (LHON) Historical Case Record Survey — COMPLETED

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