Leiomyosarcoma Clinical Trials

86 clinical trials for Leiomyosarcoma across international registries, including 24 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) — RECRUITING · PHASE1
• A Phase 1b, Open-Label Study Of REC-617, A Selective CDK7 Inhibitor, In Patients With Metastatic Or Unresectable RB1-Negative Leiomyosarcoma After Prior Systemic Therapy — RECRUITING · PHASE1
• Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors — RECRUITING · PHASE1
• STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas — RECRUITING · PHASE1
• Localized Leiomyosarcoma Biomarker Protocol — RECRUITING
• Metastatic Leiomyosarcoma Biomarker Protocol — RECRUITING
• A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors — RECRUITING · PHASE1
• A Study of Ivonescimab in People With Leiomyosarcoma — RECRUITING · PHASE2
• Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma — RECRUITING · PHASE3
• Agnostic Therapy in Rare Solid Tumors — RECRUITING · PHASE2
• A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions — RECRUITING · PHASE1
• Precision Medicine Approaches for Neoadjuvant Therapy in High-risk Sarcoma Patients — RECRUITING
• Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS) — RECRUITING · PHASE3
• Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas — RECRUITING · NA
• Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma — RECRUITING · PHASE2
• Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarcoma. — RECRUITING · PHASE2
• IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS) — RECRUITING · PHASE2
• Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma — RECRUITING · PHASE2
• MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma — RECRUITING · PHASE2
• Beliefs, Attitudes, and Response to Genetic Testing in SarcomaPatients — RECRUITING
• Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford — RECRUITING
• Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Soft Tissue Sarcoma — RECRUITING · PHASE2
• DOCETAXEL IN PREVIOUSLY TREATED SUBJECTS WITH LEIOMYOSARCOMA (ARGSARC): A RANDOMIZED, DOUBLE-BLIND, MULTI-CENTER PHASE 3 TRIAL — RECRUITING · PHASE3
• Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients — RECRUITING · PHASE1
• Study of DNA Damage, Angiogenesis, and PD-L1 Inhibitors in Advanced Solid Tumors — ACTIVE_NOT_RECRUITING · PHASE2
• A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases — ACTIVE_NOT_RECRUITING · PHASE2
• Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery — ACTIVE_NOT_RECRUITING · PHASE2
• A Study of Rucaparib and Nivolumab in People With Leiomyosarcoma — ACTIVE_NOT_RECRUITING · PHASE2
• Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma (SaLuDo) — ACTIVE_NOT_RECRUITING · PHASE3
• Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery — COMPLETED · PHASE2
• Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications — TERMINATED · PHASE1
• Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma — ACTIVE_NOT_RECRUITING · PHASE1
• Lenvatinib and Eribulin in Advanced Soft Tissue Sarcoma — COMPLETED · PHASE1
• Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas — COMPLETED · PHASE1
• A Phase II Study of Eribulin and Pembrolizumab in Soft Tissue Sarcomas — COMPLETED · PHASE2
• Treatment With Dinutuximab Beta, Zoledronic Acid and Low-dose Interleukin (IL-2) in Patients With Leiomyosarcoma — COMPLETED · PHASE2
• NM32-2668 in Adult Patients With Selected Advanced Solid Tumors — TERMINATED · PHASE1
• A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS) — TERMINATED · PHASE2
• Circulating " Cancer Cells / Macrophage " HYbrid Cells in Patients With Sarcoma, Part 2 — ACTIVE_NOT_RECRUITING · NA
• A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients — COMPLETED · PHASE1
• A Study of Nivolumab in Selected Uterine Cancer Patients — COMPLETED · PHASE2
• Cytotoxic T Cells to Treat Relapsed EBV-positive Lymphoma — COMPLETED · PHASE1
• A Study to Learn About the Study Medicine (Called Ontorpacept or TTI-621) Given Alone and in Combination With Doxorubicin in People With Leiomyosarcoma — TERMINATED · PHASE2
• Evaluation of Chest CT Versus Chest X-Ray for Lung Surveillance After Curative-Intent Resection of High-Risk Truncal-Extremity Soft Tissue Sarcoma — NOT_YET_RECRUITING · NA
• The Role of Pre-Surgical Tru - Cut Biopsy in the Management of Atypical Myometrial Lesions — NOT_YET_RECRUITING
• A Study of Unesbulin (PTC596) in Combination With Dacarbazine in Participants With Advanced Leiomyosarcoma (LMS) — COMPLETED · PHASE1
• Concordance Between Sonography Amd MRI for Presurgical Diagnosis of Uterine Mesenchymal Malignant Tumors — TERMINATED
• ATX-101 in Advanced Dedifferentiated Liposarcoma and Leiomyosarcoma — TERMINATED · PHASE2
• Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma — COMPLETED · PHASE2
• A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents — OTHER · PHASE1

Refine this search