Lennox Gastaut Syndrome Clinical Trials

70 clinical trials for Lennox Gastaut Syndrome across international registries, including 8 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• EEG Dynamics in Lennox-Gastaut Syndrome Patients Undergoing Fenfluramine Treatment — RECRUITING
• Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome — RECRUITING
• An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome — RECRUITING · PHASE3
• Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Clemizole HCl as Adjunctive Therapy in Patients with Lennox-Gastaut Syndrome — RECRUITING · PHASE3
• The Children's Adaptive Deep Brain Stimulation for Epilepsy Trial — RECRUITING · NA
• BMB-101 in Absence Epilepsy and DEE — RECRUITING · PHASE2
• Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults — RECRUITING · PHASE3
• A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO INVESTIGATE THE EFFICACY, SAFETY, AND TOLERABILITY OF LP352 IN THE TREATMENT OF SEIZURES IN CHILDREN AND ADULTS WITH DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHIES — RECRUITING · PHASE3
• Double-Blind, Placebo-Controlled, Efficacy and Safety Study of Clobazam (0.25, 0.5 and 1.0 mg/kg/day) in Patients with Lennox-Gastaut Syndrome. — COMPLETED · PHASE3
• A Placebo-Controlled, Double-Blind Comparative Study of E2080 in Lennox-Gastaut Syndrome Patients — OTHER · PHASE3
• A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults — COMPLETED · PHASE3
• A controlled clinical trial to look at the effects of treatment with rufinamide on the body, thought process development and its safety in children aged 1 to 4 years with poorly controlled Lennox Gastaut Syndrome. — OTHER · PHASE3
• Prospective German Real World Epidyolex® Beyond Seizure Study - PROGRESS — OTHER
• Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution — ACTIVE_NOT_RECRUITING · PHASE4
• A Study to Investigate the Effect of Gradual Titration to Optimize Cannabidiol Treatment in Adults With LGS — NOT_YET_RECRUITING · PHASE4
• A Randomized, Double-blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Carisbamate (YKP509) as Adjunctive Treatment for Seizures Associated with Lennox-Gastaut Syndrome in Children and Adults, with Optional Open- Label Extension — TERMINATED · PHASE3
• An Extended Access Program (EAP) for Participants Who Have Completed Rufinamide Study E2080-G000-303 — OTHER
• A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome — TERMINATED · PHASE3
• Epidyolex® in Lennox Gastaut, Dravet Syndrome and Tuberous Sclerosis Complex: an Observational Study in ITALY — ACTIVE_NOT_RECRUITING
• Sleep-Driven Adaptive Neuromodulation in Lennox-Gastaut Syndrome — NOT_YET_RECRUITING · NA
• Pallidothalamic Tracts Electrical Stimulation for Lennox-Gastaut Syndrome — ACTIVE_NOT_RECRUITING · NA
• A Study of Soticlestat in Adults and Children With Rare Epilepsies — TERMINATED · PHASE2
• A Study to Investigate the Transition of Children From 'Artisanal" Cannabidiol (CBD) to Epidiolex — NOT_YET_RECRUITING · PHASE4
• RNS System LGS Feasibility Study — ACTIVE_NOT_RECRUITING · PHASE2
• Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy — COMPLETED · PHASE2
• A Study to Investigate the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution in Children and Adults With Epileptic Encephalopathy Including Dravet Syndrome and Lennox-Gastaut Syndrome — COMPLETED · PHASE3
• Clinical Utility of Reduced EEG Home Monitoring in Fenfluramine Titration for Dravet and LGS — NOT_YET_RECRUITING · NA
• An Extended Access Program (EAP) for Perampanel — TERMINATED
• A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to Fenfluramine — TERMINATED · PHASE3
• A Study to Investigate the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) as an Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome — COMPLETED · PHASE3
• A Study to Gather Information About Overall Occurrence and New Cases of Dravet and Lennox-Gastaut Syndromes in Children, Teenagers and Adults in Spain — COMPLETED
• Intermediate-Size Expanded Access Protocol (EAP) for LP352 — OTHER
• CBD Delivery with the A-Synaptic GT4 Transdermal Delivery System in with Dravet Syndrome And/or Lennox-Gastaut Syndrome — NOT_YET_RECRUITING · PHASE1
• Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies — COMPLETED · PHASE1
• A Study on Dravet Syndrome (DS) and Lennox-Gastaut Syndrome (LGS) in Children, Teenagers and Adults in Portugal — WITHDRAWN
• A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut Syndrome — COMPLETED · PHASE3
• Carisbamate Safety Study in Adult and Pediatric Subjects With Lennox-Gastaut Syndrome — COMPLETED · PHASE1
• A Study to Assess the Safety and Tolerability of ZX008 in Children and Young Adults With Dravet Syndrome or Lennox Gastaut Syndrome Currently Taking Cannabidiol — COMPLETED · PHASE1
• Add-on Therapy With Low Dose Fenfluramine in Lennox Gastaut Epilepsy — OTHER · PHASE2
• Carisbamate in Adult & Pediatric Subjects With Lennox-Gastaut Syndrome — COMPLETED · PHASE1
• Post-marketing Surveillance of Long-term Administration of Inovelon Tablets in Patients With Lennox-Gastaut Syndrome — COMPLETED
• Long-term Cardiac Monitoring in Epilepsy — TERMINATED · NA
• Efficacy and Safety of GWP42003-P for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults — COMPLETED · PHASE3
• A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults — COMPLETED · PHASE3
• Investigation of Cognitive Outcomes With Cannabidiol Oral Solution — WITHDRAWN · PHASE4
• The Effects of Cannabidiol (CBD) on Electrical and Autonomic Cardiac Function in Children With Severe Epilepsy — TERMINATED · PHASE1
• Melatonin Versus Placebo in the Lennox-Gastaut Syndrome: Neurophysiological and Neuropsychological Effects — WITHDRAWN · PHASE4
• A PHASE 3, PROSPECTIVE, OPEN-LABEL, MULTISITE, EXTENSION OF PHASE 3 STUDIES TO ASSESS THE LONG-TERM SAFETY AND TOLERABILITY OF SOTICLESTAT AS ADJUNCTIVE THERAPY IN SUBJECTS WITH DRAVET SYNDROME OR LENNOX-GASTAUT SYNDROME (ENDYMION 2) — COMPLETED · PHASE3
• Study of Perampanel as Adjunctive Treatment for Inadequately Controlled Seizures Associated With Lennox-Gastaut Syndrome — TERMINATED · PHASE3
• A 20-WEEK MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF EPX-100 (CLEMIZOLE HYDROCHLORIDE) AS ADJUNCTIVE THERAPY IN PATIENTS WITH LENNOX-GASTAUT SYNDROME (STUDY EPX-100-003) — NOT_YET_RECRUITING

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