Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures Clinical Trials

41 clinical trials for Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures across international registries, including 9 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Comparison of complex executive functions pre- vs. post-after neurosurgical surgery intervention in patients with focal temporal and frontal epilepsy — RECRUITING
• The Significance of the Irritative Zone in Presurgical Epilepsy Diagnostics — RECRUITING
• Placebo optimization of the presurgical video-EEG long-term monitoring — RECRUITING
• Social cognition in focal epilepsy — RECRUITING
• IMAGINE-STIM Upper Rhine (Multimodal Analysis of Networks in Patients Treated with Focal Neurostimulation) — RECRUITING
• A prospective study to evaluate clinical, neurophysiological and neuropsychological consequences of epilepsy surgery in patients with symptomatic focal epilepsy refractory to pharmacotherapy — RECRUITING
• Frequency and prevalence of epilepsy among descendants of adult out-patients of an epilepsy center — RECRUITING
• Evaluation of the 24/7 EEG SubQ System for Ultra Long-Term Recording of Patients with Temporal Lobe Epilepsy — RECRUITING
• Comparative Imaging of the Hippocampal Formation in Epilepsy Patients at 3 and 7 Tesla: Is There a Diagnostic Benefit in Ultra-High-Field MRI? — RECRUITING
• Network dynamics of the electro-magnetic epileptic focus in patients with focal cortical dysplasia — OTHER
• Retrospective evaluation of a rule-constrained GPT-4-based LLM system for neuropsychological lateralization and localization in presurgical epilepsy diagnostics — OTHER
• Efficacy and tolerability of adjunctive treatment of epilepsy patients with cenobamate: An observational study — OTHER
• Psychiatric assessment prior to and after switch from levetiracetam to brivaracetam: a questionnaire study — OTHER
• Quantitative EEG- and EMG-analysis during electroconvulsive therapy — OTHER
• Laboratory parameters before and after epileptic seizures — OTHER
• A prospective randomized comparative trial to evaluate the best time-point to taper-off anticonvulsive medication after epilepsy surgery — NOT_YET_RECRUITING
• Value of Ultra High field MRI for lesion detection in patients with suspected focal epilepsy and negative 3T MRI — NOT_YET_RECRUITING
• Value of Ultra High field MRI for lesion detection in patients with suspected focal epilepsy and negative 3T MRI — OTHER
• Bone density assessment in patients with partial-onset epileptic seizures — OTHER
• Does long-term video-EEG add clinically meaningful information in patients after epilepsy surgery? — NOT_YET_RECRUITING
• Seizure Symptoms and Clinical Factors Associated with Photoparoxysmal Response in Adult Patients Attending an Epilepsy Center: A Retrospective Chart Review Study — OTHER
• Visual Illustration supporting Patient-Physician Communication in Epilepsy, a validation and reliability study of 24 seizure illustrations — OTHER
• The relation between enzyme- inducing antiepileptic drugs and Vitamin D status (assessed from the serum concentration of 25- hydroxy vitamin D, 25OHD) — OTHER
• Anatomical and functional connectivity before and after functional hemispherotomy — OTHER
• Critical Flicker-Fusion Frequency as a Method for Quantification of Neurotoxic Side Effects of Anticonvulsive Drugs — OTHER
• EASEE II – A pilot study to assess the feasibility of neurostimulation with the EASEE® System to treat medically refractory focal epilepsy — OTHER
• deep brain stimulation in patients with refractory epilepsy — OTHER
• Is there a therapeutic plasma level of cenobamate? — NOT_YET_RECRUITING
• Usage of bio-signals obtained from non-EEG sensors to detect epileptic seizures, an observational study — OTHER
• Remote assessment of Disease and Relapse in Central Nervous System Disorders (RADAR-CNS) — OTHER
• A multicenter study to examine clinical scenarios for long-term monitoring of epileptic seizures with a wearable biopotential technology — OTHER
• A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Safety, Tolerability and Efficacy of XEN1101 as Adjunctive Therapy in Focal-onset Epilepsy, with an Open-label extension — OTHER
• Course of the SARS-CoV-2 (COVID-19) infection and tolerability of the SARS-CoV-2 vaccinations in patients with epilepsies in an epilepsy outpatient clinic — NOT_YET_RECRUITING
• A 12-month, non-interventional, observational multinational study to evaluate effectiveness, tolerability, and quality of life of brivaracetam adjunctive therapy in earlier treatment lines in adult patients with history of partial-onset seizures in daily clinical practice. — NOT_YET_RECRUITING
• Forms of anxiety in patients with epilepsy — NOT_YET_RECRUITING
• Is the anticonvulsant activity of levetiracetam dose-dependent? — OTHER
• High-frequency oscillations in high-density scalp electroencephalography. Can physiologic and pathologic high-frequency oscillations be distinguished in the high-density scalp electroencephalography using functional paradigms? — OTHER
• The period prevalence and characteristics of rare disorders in patients with epilepsy at 2 epilepsy centers, Germany — NOT_YET_RECRUITING
• Clinical Use of Different Fiber Tractography Methods in Epilepsy Surgery — OTHER
• Therapeutic range of Brivaracetam, a historical observational study to define a therapeutic range — NOT_YET_RECRUITING
• Postoperative volumetry after hippocampus-sparing epilepsy surgery — NOT_YET_RECRUITING

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