Locally Advanced Malignant Solid Neoplasm Clinical Trials

32 clinical trials for Locally Advanced Malignant Solid Neoplasm across international registries, including 8 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial — RECRUITING · PHASE2
• Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, DURVA+ Trial — RECRUITING · PHASE2
• Mobile Health Application (PACT) to Improve Engagement in Advance Care Planning — RECRUITING · NA
• Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors — RECRUITING · PHASE1
• Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types — RECRUITING
• Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors — RECRUITING · PHASE1
• Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors — RECRUITING · PHASE2
• Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors — RECRUITING · PHASE2
• Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations — ACTIVE_NOT_RECRUITING · PHASE2
• Testing the Combination of New Anti-cancer Drug Peposertib With Avelumab and Radiation Therapy for Advanced/Metastatic Solid Tumors and Hepatobiliary Malignancies — ACTIVE_NOT_RECRUITING · PHASE1
• Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With PTEN/AKT Mutations, A ComboMATCH Treatment Trial — SUSPENDED · PHASE2
• Testing AZD1775 in Advanced Solid Tumors That Have a Mutation Called SETD2 — ACTIVE_NOT_RECRUITING · PHASE2
• Adoption of Audio Recording in the Outpatient Supportive Care Center — NOT_YET_RECRUITING
• Physical Activity With or Without Dexamethasone in Reducing Cancer-Related Fatigue in Patients With Locally Advanced, Metastatic, or Recurrent Cancer — ACTIVE_NOT_RECRUITING · PHASE2
• Exploratory Study on the Efficacy and Safety of Trastuzumab Rezetecan in the Treatment of HER2-Expressiong Advanced Solid Tumor — NOT_YET_RECRUITING · PHASE2
• Ceritinib and Everolimus in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIB-IV Non-small Cell Lung Cancer — ACTIVE_NOT_RECRUITING · PHASE1
• Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors — ACTIVE_NOT_RECRUITING · PHASE2
• CMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma — TERMINATED · PHASE1
• Assessment of Verbal Comprehension and Cognitive Processes in Patients Admitted to the Palliative and Supportive Care Unit — SUSPENDED
• Design and Testing of a Web-Based Tool for the Improvement of End-of-Life Planning in Patients With Advanced Cancer — COMPLETED · NA
• STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma — WITHDRAWN · PHASE1
• Testing the Safety of CB-5339 in Patients With Cancer — WITHDRAWN · PHASE1
• PLAN Intervention to Enhance Engagement of Latino Cancer Patients in Advanced Care Planning — COMPLETED · NA
• Pembrolizumab Before Surgery for the Treatment of Mismatch Repair Deficient Locally Advanced Solid Cancers — COMPLETED · PHASE2
• Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer — COMPLETED · PHASE1
• Distress Associated with Coronavirus Disease 2019 and Telehealth on Supportive Care Patients with Advanced Cancer — COMPLETED
• Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer — COMPLETED · PHASE1
• Integrative Palliative Care/Psycho-Oncology Telehealth Intervention in Patients With Advanced Cancer — COMPLETED · NA
• Pevonedistat and Pembrolizumab for the Treatment of dMMR/MSI-H Metastatic or Locally Advanced Unresectable Solid Tumor — TERMINATED · PHASE1
• Alpelisib in Combination With Carboplatin in Patients With Solid Tumors and HPV-Positive Squamous Cell Carcinoma — WITHDRAWN · PHASE1
• BAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors — WITHDRAWN · PHASE1
• Brigatinib in Treating Patients With ALK and ROS1 Gene Alterations and Locally Advanced or Metastatic Solid Cancers — WITHDRAWN · PHASE2

Refine this search