Locally Advanced or Metastatic Breast Cancer Clinical Trials

26 clinical trials for Locally Advanced or Metastatic Breast Cancer across international registries, including 7 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Phase 2 Study to Evaluate the Efficacy, Safety and Pharmacokinetics of YL202 in Patients With BC — RECRUITING · PHASE2
• The Efficacy of Compression/Ice Gloves/Socks in Patients With UTD1-induced Neuropathy. — RECRUITING · NA
• A Study to Evluate Efficacy and Safety of HRS-8080 Combined With Dalpiciclib in Patients With Advanced or Metastatic Breast Cancer Resistant to Adjuvant Endocrine Therapy. — RECRUITING · PHASE3
• YL202 Versus Treatment of Physician's Choice in Patients With HR+/HER2- Breast Cancer — RECRUITING · PHASE3
• Safety and Efficacy of SPH4336 in Combination With Endocrine Therapy in the Treatment of Locally Advanced or Metastatic Breast Cancer — RECRUITING · PHASE2
• Phase II/III Study of SPH4336 Combined With Letrozole vs Placebo Combined With Letrozole in First-line Treatment of Breast Cancer — RECRUITING · PHASE2
• Utidelone Versus Docetaxel in HER2-negative Locally Advanced or Metastatic Breast Cancer — RECRUITING · PHASE3
• A phase II open label single-arm study of E7389 in patients with locally advanced or metastatic breast cancer, previously treated with anthracycline, taxane, and capecitabine therapy, refractory to the last prior therapy for their disease. — COMPLETED · PHASE2
• A Randomized, Double-Blind, Phase 2 Trial of Fulvestrant Plus Enzastaurin versus Fulvestrant Plus Placebo in Aromatase Inhibitor-Resistant Metastatic Breast Cancer — COMPLETED · PHASE2
• A study to investigate whether adding a new hormone treatment for breast cancer, called Irosustat, to current hormone treatment (aromatase inhibitor) can affect the growth of breast cancer. — COMPLETED · PHASE2
• A Phase II, Randomised, Open-Label, Multicentre Study of AS1402 in Combination with Letrozole as First Line Treatment in Postmenopausal Women with Locally Advanced or Metastatic Breast Cancer. — ACTIVE_NOT_RECRUITING · PHASE2
• A Study of SIM0270 Combined With Everolimus vs. Treatment of Physician's Choice in Patients With ER+/HER2- Advanced Breast Cancer (SIMRISE) — ACTIVE_NOT_RECRUITING · PHASE3
• Antibody-based PET Imaging and Treatment Response in Breast Cancer Treated With an Antibody-drug Conjugate. — NOT_YET_RECRUITING · PHASE2
• A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer) — ACTIVE_NOT_RECRUITING · PHASE3
• A Phase IIIB Study to Evaluate the Use of Capivasertib in Combination With Fulvestrant in Patients With Advanced Breast Cancer Who Have Relapsed/Progressed on ET and CDK4/6 Inhibitor Reflecting Real World Clinical Practice in Spain — ACTIVE_NOT_RECRUITING · PHASE3
• An Open Label, Randomized, Multicenter Study Comparing the Efficacy and Safety of the Combination of Lasofoxifene and Abemaciclib to the Combination of Fulvestrant and Abemaciclib for the Treatment of Pre- and Postmenopausal Women and Men with Locally Advanced or Metastatic ER+/HER2− Breast Cancer with an ESR1 Mutation — TERMINATED · PHASE3
• Evaluation of Lasofoxifene Versus Fulvestrant in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation — COMPLETED · PHASE2
• A Study of Entinostat in Combination With Fulvestrant for the Treatment of Locally Advanced or Metastatic Breast Cancer — NOT_YET_RECRUITING · PHASE2
• A Study of SHR-A1811 and Fulvestrant, With or Without HS-10352, in Locally Advanced or Metastatic Breast Cancer Patients — NOT_YET_RECRUITING · PHASE1
• GB491 Combined With Fulvestrant for HR+ HER2- Locally Advanced or Metastatic Breast Cancer — COMPLETED · PHASE3
• To Assess Efficacy and Safety of Oral Reparixin in Patients With Fatigue and Locally Advanced / Metastatic Breast Cancer — WITHDRAWN · PHASE2
• Incidence and Resolution of Eribulin-Induced Peripheral Neuropathy — COMPLETED
• Weekly Utidelone in HER2-negative Inoperable Locally Advanced or Metastatic Breast Cancer — OTHER · PHASE2
• Utidelone Plus Capecitabine Versus Taxane Plus Capecitabine in HER2-negative Locally Advanced or Metastatic Breast Cancer — NOT_YET_RECRUITING · PHASE3
• A Study to Investigate the Efficacy and Safety of Eribulin in Korean Breast Cancer Participants — COMPLETED
• Phase I Study of Ixabepilone Plus Lapatinib With or Without Capecitabine in the Treatment of Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer — TERMINATED · PHASE1

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