Locally Advanced or Metastatic Solid Tumors Clinical Trials

55 clinical trials for Locally Advanced or Metastatic Solid Tumors across international registries, including 18 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors — RECRUITING · PHASE1
• PTT-936 Alone or in Combination in Patients With Locally Advanced or Metastatic Solid Tumors — RECRUITING · PHASE1
• A Phase 1/2, Multicenter, Open-label, Dose-escalation, and Dose-expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamic, and Antitumor Activity of CR-001 in Adult Participants with Locally Advanced or Metastatic Solid Tumors. — RECRUITING · PHASE2
• A Phase 1 Open-Label Study to Evaluate the Efficacy and Safety of ABBV-400 in Select Advanced Solid Tumor Indications — RECRUITING · PHASE1
• Study of XB010 in Subjects With Solid Tumors — RECRUITING · PHASE1
• A First-in-human Phase I Study to Evaluate EMB-15 in Patients With Locally Advanced or Metastatic Solid Tumors. — RECRUITING · PHASE1
• BC3195 in Combination With Pembrolizumab in Participants With Locally Advanced or Metastatic Solid Tumors — RECRUITING · PHASE1
• A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors — RECRUITING · PHASE1
• A Study of YL202 in Patients With Advanced Solid Tumors — RECRUITING · PHASE2
• A Study of YL202 in Selected Patients With Advanced Solid Tumors — RECRUITING · PHASE2
• A Study of BL-M05D1 in Patients With Locally Advanced or Metastatic Solid Tumors — RECRUITING · PHASE1
• A Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of ATG 037 Monotherapy and Combination Therapy With Pembrolizumab in Patients With Advanced Solid Tumors — RECRUITING · PHASE1
• A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies — RECRUITING · PHASE1
• Clinical Trial to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of DA-4505 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Locally Advanced or Metastatic Solid Tumors — RECRUITING · PHASE1
• Study of IBI3005 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors — RECRUITING · PHASE1
• A Study of TYK-00540 in Adult Patients With Solid Tumors — RECRUITING · PHASE1
• IFNα Expressing Mesenchymal Stromal Cells for Locally Advanced/Metastatic Solid Tumors — RECRUITING · PHASE1
• A Study of XZP-5955 Tablets in Patients With NTRK or ROS1 Fusion Positive Locally Advanced or Metastatic Solid Tumors — RECRUITING · PHASE1
• A dose escalation and expansion study of XB010 as a single agent and combination therapy in subjects with locally advanced or metastatic solid tumors — NOT_YET_RECRUITING · PHASE1
• A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors — ACTIVE_NOT_RECRUITING · PHASE1
• A Dose-Escalation Study of SPYK04 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion). — COMPLETED · PHASE1
• A Study of ASP388B Given by Itself and With Standard Therapies in Participants With Solid Tumors — NOT_YET_RECRUITING · PHASE1
• Clinical Study of SM3321 With Solid Tumors — COMPLETED · PHASE1
• HERTHENA-PanTumor01: A Phase 2, Multicenter, Multicohort, Open-Label, Proof of Concept Study of Patritumab Deruxtecan (HER3-DXd) in Subjects with Locally Advanced or Metastatic Solid Tumors — TERMINATED · PHASE2
• An Open-Label, Multicenter, Phase 1 Trial to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of TLN-372 as a Single Agent and in Combination with Other Anti-Tumor Agents, in Patients with Advanced KRAS Mutant Solid Tumors — TERMINATED · PHASE2
• ADCX-020 for the treatment of patients with locally advanced or metastatic cancers — TERMINATED · PHASE1
• An Open-label Dose-Escalation Study to Evaluate XmAb24306 as a Single Agent and in Combination with Atezolizumab in Patients with Locally Advanced or Metastatic Solid Tumors — OTHER · PHASE1
• A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination with Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors — TERMINATED · PHASE1
• A Phase I study of STA551 and STA551 in combination with atezolizumab in patients with solid tumours — TERMINATED · PHASE1
• A study evaluating the safety, tolerability, pharmacokinetics, and activity of RO7566802 given alone and in combination with atezolizumab in patients with locally advanced or metastatic solid tumor malignancies — OTHER · PHASE1
• A Study to Evaluate ANS014004 in Subjects With Locally Advanced or Metastatic Solid Tumors — ACTIVE_NOT_RECRUITING · PHASE1
• A Study to Evaluate the Safety, Tolerability, PK, PD, and Preliminary Efficacy of CS01 in Patients With Locally Advanced or Metastatic Solid Tumors — ACTIVE_NOT_RECRUITING · PHASE1
• A Single-arm, Open-label, Multicenter, Phase Ib/II Clinical Trial of CVL237 Tablets in Combination With Serplulimab Injection for the Treatment of Advanced Solid Tumors With PTEN Loss or Low Expression — NOT_YET_RECRUITING · PHASE2
• A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7496353 in Combination with a Checkpoint Inhibitor with or without Standard-of-Care Chemotherapy in Patients with Locally Advanced or Metastatic Solid Tumors — OTHER · PHASE1
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-Tumor Activity of Inavolisib in Combination with Paclitaxel in Patients with Locally Advanced or Metastatic Solid Tumors — OTHER · PHASE1
• Phase 2 Clinical Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of GH21 Capsules Combined With D-1553 Tablets in Subjects With Locally Advanced or Metastatic Solid Tumors With the KRASG12C Mutation — NOT_YET_RECRUITING · PHASE2
• A Dose-escalation Study of LUNA18 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion). — TERMINATED · PHASE1
• A Study to Investigate the Safety and Effectiveness of RO7759065 in Combination with Atezolizumab in Participants with Locally Advanced or Metastatic Cancer — OTHER · PHASE1
• IN10018 Combination Therapy in Previously-treated Locally Advanced or Metastatic Solid Tumor Patients — COMPLETED · PHASE1
• Assessment of Safety and Preliminary Clinical Efficacy with BAT6005 in Advanced Malignant Solid Tumors — COMPLETED · PHASE1
• Study to Assess Safety, Tolerability and Clinical Activity of BGB-290 in Combination With Temozolomide (TMZ) in Participants With Locally Advanced or Metastatic Solid Tumors — COMPLETED · PHASE1
• A Phase 1 Study of TAS0612 in Patients with Locally Advanced or Metastatic Solid Tumors — OTHER · PHASE1
• MPDL3280A-treatment-IST-UMCG — OTHER · PHASE2
• First-In-Human (FIH) Study of W0180 as Single Agent and in Combination With Pembrolizumab in Adults With Locally Advanced or Metastatic Solid Tumors — TERMINATED · PHASE1
• Javelin BRCA/ATM: Avelumab Plus Talazoparib in Patients With BRCA or ATM Mutant Solid Tumors — TERMINATED · PHASE2
• HLX35(EGFR×4-1BB Bispecific) in Patients With Advanced or Metastatic Solid Tumors — OTHER · PHASE1
• HLX301 (TIGIT×PDL1 Bispecific) in Patients With Locally Advanced or Metastatic Solid Tumors — OTHER · PHASE1
• Study of BC3195 Monotherapy in Patients With Advanced Solid Tumors — OTHER · PHASE1
• Study of Anti-5T4 CAR-raNK Cell Therapy in Locally Advanced or Metastatic Solid Tumors — OTHER · PHASE1
• Study of AMV564 in Subjects With Advanced Solid Tumors — OTHER · PHASE1

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