Locally Advanced Rectal Carcinoma Clinical Trials

27 clinical trials for Locally Advanced Rectal Carcinoma across international registries, including 7 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer — RECRUITING · PHASE1
• Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally Advanced Rectal Cancer — RECRUITING · PHASE2
• Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer — RECRUITING · PHASE3
• A Series of Neoadjuvant Chemoradiotherapy Combined With Immunotherapy for Locally Advanced Rectal Cancer — RECRUITING · PHASE2
• Exercise for Improving Long-course Chemoradiotherapy Efficacy in People With Locally Advanced Rectal Cancer — RECRUITING · PHASE1
• Circulating Tumor DNA-guided Neoadjuvant Treatment Strategy for Locally Advanced Rectal Cancer — RECRUITING · PHASE2
• Organ Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local Excision — RECRUITING · NA
• Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers — ACTIVE_NOT_RECRUITING · PHASE2
• Longitudinal Multimodal Response Assessment During Neoadjuvant Treatment of Rectal Cancer — ACTIVE_NOT_RECRUITING
• An Investigational Scan (64Cu-Labeled M5A Antibody) in Combination With SOC Chemotherapy and Radiotherapy in Locally Advanced Rectal Cancer — ACTIVE_NOT_RECRUITING · PHASE1
• Preoperative, Adaptive Radiotherapy Concomitant to Chemotherapy for Rectal Adenocarcinoma (Adaptive Rectal Cancer Trial 02) — NOT_YET_RECRUITING · NA
• Neoadjuvant FOLFOXIRI and Chemoradiotherapy Versus Neoadjuvant CAPOX/FOLFOX and Chemoradiotherapy Followed by Surgery or a Watch-and-Wait Approach in High Risk Locally Advanced Rectal Cancer — NOT_YET_RECRUITING · PHASE3
• Exercise for Improving Radiotherapy Efficacy in Rectal Cancer — WITHDRAWN · NA
• MRI T1 Relaxation Time in Rectal Cancer — COMPLETED
• Reducing the Resection Range After Neoadjuvant Therapy for Locally Advanced Upper Rectal and Rectosigmoid Junction Cancers — ACTIVE_NOT_RECRUITING · NA
• Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation — ACTIVE_NOT_RECRUITING · PHASE2
• Deep Learning Based MRI Radiomics in Predicting the Clinical Risk of Locally Advanced Rectal Cancer — COMPLETED
• Endorectal Brachytherapy for Rectal Cancer — SUSPENDED · PHASE2
• Testing the Addition of a Radiation Sensitizing Drug, IPdR, to the Usual Chemotherapy Treatment (Capecitabine) During Radiation Therapy for Rectal Cancer — TERMINATED · PHASE1
• Radiological Markers in Locally Advanced Rectal Cancer — NOT_YET_RECRUITING
• Neoadjuvant Cadonilimab Plus Chemotherapy Following Short-Course Radiotherapy in Locally Advanced Rectal Cancer — COMPLETED · PHASE2
• Assessment of Efficacy of Neoadjuvant Therapy in Locally Advanced Rectal Cancer — COMPLETED
• Evaluating PD-1/PD-L1 in Locally Advanced Rectal Cancer by Quantitative Fluorescence Molecular Endoscopy — OTHER · PHASE1
• Comparison of the Clinical Response of Total Neoadjuvant Treatment of Two Methods of Long-term or Short-term Chemoradiotherapy in Rectal Cancer — OTHER · NA
• Neoadjuvant Envafolimab in Resectable and Locally Advanced MSI-H/dMMR Rectal Cancer — OTHER
• Prospective Study of Short Course Radiation Therapy Followed by Neoadjuvant Chemotherapy and Surgery in Locally Advanced Rectal Cancer — COMPLETED · PHASE2
• Ferumoxytol-Enhanced MRI in Imaging Lymph Nodes in Patients With Locally Advanced Rectal Cancer — TERMINATED · PHASE1

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