Major Depressive Episode Clinical Trials

76 clinical trials for Major Depressive Episode across international registries, including 23 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Signature Response to Light Therapy in Unipolar and Bipolar Major Depressive Episode (MDE) — RECRUITING · NA
• Cohort of Patients Suffering From Major Depressive Episode With Evaluation of Sleep, Circadian Rhythms and Psychiatric Disorders — RECRUITING
• EEG Microstate Parameters and Neuroinflammatory Biomarkers in Patients With Treatment-Resistant Major Depressive Disorder Receiving ECT — RECRUITING
• EEG Microstate and Neuroinflammatory Biomarkers in Older Age Patients With Major Depressive Disorder Receiving ECT — RECRUITING
• Belief Update: The Effects of Depression and Antidepressants in Older People — RECRUITING · NA
• Feasibility of Home-Based Intermittent 60Hz Light Therapy for Major Depressive Disorder (MDD) — RECRUITING · NA
• tDCS: Sleep to Mood in Depression (S2M-D) — RECRUITING · NA
• A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD) — RECRUITING · PHASE2
• Personalized Ultrasonic Brain Stimulation for Depression (R61) — RECRUITING · PHASE1
• LHC-CIDI-5 in Hong Kong — RECRUITING
• University of Iowa Interventional Psychiatry Service Patient Registry — RECRUITING
• Presynaptic Imaging in Major Depressive Episodes After COVID-19 — RECRUITING
• At-Home tDCS as Maintenance Therapy — RECRUITING · NA
• Feasibility and Efficacy of rTMS in Depression in Patients With Autism Spectrum Disorder (ASD) — RECRUITING · NA
• Validation of a Composite Medical Device Using a Blood Biomarker-based Algorithm and MDQ for the Diagnosis of Bipolar Disorder — RECRUITING · NA
• Early Effects of Ketamine vs Placebo With Venlafaxine in Severe Depression Patients — RECRUITING · PHASE3
• The Impact of Coach-guided Risk Communication on the Risk of Major Depression — RECRUITING · NA
• Add-on Buprenorphine at Analgesic Doses for the Treatment of Severe Suicidal Ideas During a Major Depressive Episode — RECRUITING · PHASE3
• Metabolomics During ElectroConvulsivoTherapy — RECRUITING · NA
• Patient-oriented Randomized Pragmatic Feasibility Trial with RTMS in Depression and Anxiety — RECRUITING · NA
• Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot Study — RECRUITING
• Accelerated Intermittent Theta Burst in Treatment-Naive Adolescents — RECRUITING · NA
• Comparing Uni- and Bi-lateral TBS in Major Depression — RECRUITING · NA
• Biomarker Discovery for Suicide Precision Circuit Therapeutics — NOT_YET_RECRUITING
• Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder — COMPLETED
• Circuit-Based Approach to Suicide: Biomarkers, Predictors, and Novel Therapeutics — COMPLETED · NA
• Major Depression and Messenger RNAs — COMPLETED · NA
• The RAFT ECT Study — COMPLETED · NA
• A Text Messaging Intervention to Reduce Perinatal Depression Risk — COMPLETED · NA
• Terrorist Attack - Continuity of Care — COMPLETED
• Beta-arrestins and Response to Venlafaxine in Major Depressive Disorder (MDD) (DEPARRESTCLIN) — COMPLETED · PHASE4
• Neuroinflammation in COVID-19 and Depression — COMPLETED
• Microglial Activation in Inflammatory Bowel Disease — COMPLETED
• SAINT for MDD in an Inpatient Setting Follow-on — TERMINATED · PHASE2
• The Effects of SAINT® Neuromodulation System on Explicit and Implicit Suicidal Cognition — TERMINATED · PHASE2
• Personalized Repetitive Transcranial Magnetic Stimulation Treatment for Major Depressive Episode — COMPLETED · NA
• Ketamine As an Adjunctive Therapy for Major Depression (2) — COMPLETED · PHASE3
• Affective Touch, Hedonia and Suicidal Behavior — COMPLETED · NA
• Depression-Reduction by Accelerated Personalized NeuroModulation and Its Effects on Sleep — COMPLETED
• Personalized Ultrasonic Brain Stimulation for Depression — ACTIVE_NOT_RECRUITING · PHASE1
• Reward Processing and Depressive Subtypes: Identifying Neural Biotypes — OTHER
• Universal vs. Targeted School Screening for Adolescent Major Depressive Disorder — COMPLETED · NA
• Medibio DDA Confirmatory Performance Study — COMPLETED
• A Study to Evaluate SAGE-217 in Participants With Bipolar I/II Disorder With a Current Major Depressive Episode — COMPLETED · PHASE2
• Predict MDE Outcomes After MST — COMPLETED · NA
• Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) Treatment for Major Depressive Episode — OTHER · NA
• ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD) — COMPLETED · PHASE2
• Mobile Observation Of Depression — COMPLETED
• Depressive Symptoms and Subjective Stress in the Course of the Menstrual Cycle - an Ambulatory Assessment Study. — COMPLETED
• Antidepressant Efficacy of Psychotherapy and Citalopram in Patients With Breast Cancer and Major Depression — TERMINATED · PHASE2

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