Malaria Clinical Trials

881 clinical trials for Malaria across international registries, including 25 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge — RECRUITING
• Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates — RECRUITING
• Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants — RECRUITING
• Assessing Vaccine Effectiveness of R21/Matrix-M Across Malaria Transmission Settings (AVERT) — RECRUITING
• Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays — RECRUITING · PHASE1
• Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection — RECRUITING
• PfSPZ-LARC2 Vaccine in Women of Child-bearing Potential (WOCBP) in Mali — RECRUITING · PHASE2
• Safety and Efficacy of Imatinib in Combination With Artemether-Lumefantrine for Uncomplicated Malaria — RECRUITING · PHASE2
• Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali — RECRUITING
• FocaL Mass Drug Administration for Vivax Malaria Elimination — RECRUITING · PHASE3
• Field Trial of PfSPZ-LARC2 Vaccine in Burkinabe Adults — RECRUITING · PHASE2
• Pregnancy Registry in Mali — RECRUITING
• Dose Finding Trial of R21/Matrix-M in School Children — RECRUITING · PHASE2
• Effectiveness of Malaria Vaccines in Reducing the Risk of Invasive Non-typhoidal Salmonella Disease — RECRUITING
• OPTImizing Malaria And HIV Treatment in a Shifting Landscape in Africa — RECRUITING · PHASE4
• Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective — RECRUITING
• Safety of Antimalarials in the FIRst trimEster — RECRUITING · PHASE3
• A Study to Assess the Safety and Immunogenicity of a Vaccine Against Malaria in Healthy Children Aged 5-60 Months — RECRUITING · PHASE2
• L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE) — RECRUITING · NA
• ACT vs CQ With Tafenoquine for P. Vivax Mono-infection — RECRUITING · PHASE4
• Strengthening the Evidence for Policy on the RTS,S/AS01 Malaria Vaccine — RECRUITING
• Evaluation of Artesunate in Infants Being Treated for Severe Malaria — RECRUITING
• Seasonal R21 Mass Vaccination for Malaria Elimination — RECRUITING · PHASE3
• Malaria Molecular Surveillance in Mozambique (Phase 2) — RECRUITING
• Observational Study of the Safety of Intravenous Artesunate Treatment of Pregnant Women and Their Infants — RECRUITING
• Impact of long-lasting insecticide treated bednets with and without piperonyl butoxide (PBO) on malaria indicators in Uganda — ACTIVE_NOT_RECRUITING
• A phase I/IIa sporozoite challenge study to assess the safety, immunogenicity and protective efficacy of new malaria vaccine candidates; AdCh63 AMA1, MVA AMA1, AdCh63 MSP1, MVA MSP1, AdCh63 ME-TRAP & MVA ME-TRAP. — COMPLETED · PHASE2
• Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1) — SUSPENDED · PHASE1
• Safety, Tolerability, Pharmacokinetics, and Mosquitocidal Activity of Lotilaner in Healthy Participants in Mali. — NOT_YET_RECRUITING · PHASE1
• A Study of Oral E1018 in Healthy Adult Participants — ACTIVE_NOT_RECRUITING · PHASE1
• First-in-Human PfSPZ-LARC2 Vaccination/CHMI — ACTIVE_NOT_RECRUITING · PHASE1
• A Study of the Plasmodium Falciparum Malaria Vaccine Candidate Pfs48/45 in Matrix-M Adjuvant in the UK — TERMINATED · PHASE1
• Evaluation of a Comprehensive School Health Programme in Zambia — ACTIVE_NOT_RECRUITING · NA
• A Clinical Study of Piperaquine, Pyronaridine, and Artesunate Administered in Combination in Healthy Adults — NOT_YET_RECRUITING · PHASE1
• Monoclonal Antibodies in Children With Severe Anaemia or Severe Malaria to Prevent Malaria After Hospital Discharge — ACTIVE_NOT_RECRUITING · PHASE3
• R21/MM Dosing, Presentations, and Preservatives — NOT_YET_RECRUITING · PHASE4
• Challenge Trial of PfSPZ-LARC2 Vaccine in Burkina Faso — NOT_YET_RECRUITING · PHASE1
• This is a Clinical Study to Assess Whether the Combination of SJ733 and Tafenoquine Will be a Safe and Rapidly Acting Anti-malarial for the Radical Cure of P. Vivax Malaria — NOT_YET_RECRUITING · PHASE2
• A clinical trial of MK-3868 in healthy participants (MK-3868-001) — TERMINATED · PHASE1
• Integrating the Guardian Spatial Emanator Within AVENIR II — NOT_YET_RECRUITING · NA
• A Study to Assess the Safety and Effectiveness of Two Experimental Malaria Vaccines — COMPLETED · PHASE1
• Study to Assess Safety and Clinical Responses With Coartem® Baby Dispersible Tablets in Paediatric Patients Weighing 2 to <5 kg With Uncomplicated Malaria — NOT_YET_RECRUITING · PHASE4
• Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults — COMPLETED · PHASE1
• Antimalarial prophylactic efficacy of a weekly dose atovaquone-proguanil — TERMINATED · PHASE2
• L9LS in Women of Childbearing Potential in Mali — COMPLETED · PHASE2
• Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP) — ACTIVE_NOT_RECRUITING · PHASE3
• Intermittent Preventive Treatment of Malaria in School-age Children to Decrease Community Transmission — NOT_YET_RECRUITING · PHASE4
• Safety, Tolerability, Immunogenicity and Protective Efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian Adults Against Naturally-Transmitted Malaria — COMPLETED · PHASE2
• Star Homes Project 2 — COMPLETED · NA
• Malaria CVD 36000; Gates INV090205 — NOT_YET_RECRUITING · PHASE1

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