Malaria,Falciparum Clinical Trials

171 clinical trials for Malaria,Falciparum across international registries, including 8 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Drug-Interaction Assessment of GSK3772701 in Healthy Male and Female Participants Aged 18 to 55 Years — RECRUITING · PHASE1
• Safety, Tolerability and Efficacy of PfSPZ-LARC2 Vaccine Against CHMI in Malaria-Naïve Adults — RECRUITING · PHASE1
• Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of LAI MMV055 Alone and in Combination With MMV371 in Healthy Participants — RECRUITING · PHASE1
• Serological Testing and Treatment for Plasmodium Vivax Malaria: a Trial in Ethiopia and Madagascar — RECRUITING · PHASE3
• A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 Combined With R21/Matrix-M (a "Multi-stage" Malaria Vaccine) — RECRUITING · PHASE1
• Assessing the Feasibility of Combining Dihydroartemisinin Piperaquine and Primaquine for Malaria Mass Drug Administration in High Endemic Communities in the Eastern Region of Ghana — RECRUITING · NA
• An Observational Study to Assess Effectiveness and Safety of The R21/Matrix-M Malaria Vaccine — RECRUITING
• A Study to Test Experimental Blood Stage Malaria Vaccine in Burkina Faso. — RECRUITING · PHASE1
• Preventing Malaria in School Children to Protect the Whole Community in Rural Blantyre District, Malawi — COMPLETED · PHASE4
• A Study to Assess the Safety and Effectiveness of Two Experimental Malaria Vaccines — COMPLETED · PHASE1
• A Study to Investigate the Safety of GSK4024484 in Healthy Adult Participants — COMPLETED · PHASE1
• A Phase 2A Study of a Novel Antimalarial Pyrrolidinamide in Adult Patients With Uncomplicated P. Falciparum Malaria — NOT_YET_RECRUITING · PHASE2
• First-in-Human Dose-escalation of GSK4425689A: Safety, Tolerability, and PK in Healthy Adults — NOT_YET_RECRUITING · PHASE1
• Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics — ACTIVE_NOT_RECRUITING · PHASE4
• Pharmacokinetics of Antimalarials in Breastfeeding Ugandan Mother-infant Pairs — ACTIVE_NOT_RECRUITING
• Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV371 LAI in Healthy Participants — COMPLETED · PHASE1
• Safety and PK of MMV371 LAI in Healthy Adults and Adolescents in Rwanda — NOT_YET_RECRUITING · PHASE1
• Age De-escalation Safety Trial of PfSPZ-LARC2 Vaccine in Burkina Faso — COMPLETED · PHASE1
• A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™ — ACTIVE_NOT_RECRUITING · PHASE1
• A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 With Matrix-M in Combination With R21/Matrix-M — ACTIVE_NOT_RECRUITING · PHASE2
• CHILD (Child Health and Infection With Low Density) Malaria — COMPLETED · NA
• Health Systems Implementation and Molecular Surveillance of Multiple First-Line Treatments for Uncomplicated Malaria in Western Kenya — COMPLETED
• Safety, Pharmacokinetics, and Plasmodium Falciparum Transmission-reducing Activity of Monoclonal Antibody TB31F in Mali — COMPLETED · PHASE1
• Perennial Malaria Chemoprevention in the Malaria Vaccine Era — NOT_YET_RECRUITING · PHASE4
• MDA and Targeted Control Against Plasmodium Carriage in the Sahel — ACTIVE_NOT_RECRUITING · NA
• Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum — COMPLETED · PHASE1
• Safety and Immunogenicity of Recombinant Pichia Pastoris AMA1-DiCo Candidate Malaria Vaccine With GLA-SE and Alhydrogel ® as Adjuvant in Healthy Malaria Non-Exposed European and Malaria Exposed African Adults — COMPLETED · PHASE1
• Safety and Immunogenicity of SUM-101 Malaria Vaccine in Children and Infants Living in Burkina Faso — ACTIVE_NOT_RECRUITING · PHASE1
• IGHID 12334 - After the Flood: Optimal Strategies to Prevent Malaria Epidemics Caused by Severe Flooding — ACTIVE_NOT_RECRUITING · NA
• Safety, Immunogenicity and Efficacy of R21 Matrix-M in 5-17 Month Old Children in Nanoro, Burkina Faso — COMPLETED · PHASE1
• Understanding and Maximizing the Community Impact of Antimalarial Treatment (INDIE-SMC) — COMPLETED · NA
• Safety and Immunogenicity of the Malaria Vaccine, R21/MatrixM, in Healthy Thai Adults — COMPLETED · PHASE2
• Clinical Practices for Treating Severe Malaria Caused by P. Falciparum — COMPLETED
• Pyronaridine in Healthy Adult Participants Infected With Blood Stage Malaria — COMPLETED · PHASE1
• Private Medicine Retailer-based Trial of Malaria Tests and Conditional Treatment Subsidies Among Patients With Fever — COMPLETED · PHASE4
• A Phase Ia Clinical Trial to Assess the Safety and Immunogenicity of the Blood-stage Malaria Candidate Vaccines RH5.1 in Matrix-M and R78C in Matrix-M in Healthy UK Adults — ACTIVE_NOT_RECRUITING · PHASE1
• Experimental Malaria Infection of Healthy Malaria-Naive Adults by Mosquito Bite With the Genetically Modified Plasmodium Falciparum NF54/iGP3 GAP — NOT_YET_RECRUITING · PHASE1
• Safety and Efficacy of R0.6C Vaccine — COMPLETED · PHASE1
• A Study to Determine if New Types of Malaria Vaccines Are Safe, Effective and Lead to Immunity in Kenyan Adults — TERMINATED · PHASE2
• First-in-Human Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV367 — COMPLETED · PHASE1
• Safety, Immunogenicity and ex Vivo Efficacy of Pfs25-IMX313/Matrix-M in Healthy Volunteers in Bagamoyo, Tanzania. — TERMINATED · PHASE1
• Durability of Protection After Single Immunisation With GA2 Sporozoites (CoGA-Rechallenge) — NOT_YET_RECRUITING · PHASE1
• Malaria Vaccine Pilot Evaluation — COMPLETED
• A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI — TERMINATED · PHASE1
• Safety and Immunogenicity of RH5.1/Matrix-M in Adults and Infants Living in Tanzania — COMPLETED · PHASE1
• Effectiveness and Safety of Intermittent Preventive Treatment for Malaria Using Either Dihydroartemisinin-piperaquine or Artesunate-amodiaquine in Reducing Malaria Related Morbidities and Improving Cognitive Ability in School-aged Children in Tanzania — COMPLETED · PHASE3
• A Study to Compare Two Dosing Regimens for a New Malaria Vaccine — ACTIVE_NOT_RECRUITING · PHASE1
• Gametocytocidal and Transmission-blocking Efficacy of ASAQ and ALAQ With or Without PQ in Mali — COMPLETED · PHASE2
• Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) Extension Study — COMPLETED · PHASE3
• Short Course Radical Cure of P. Vivax Malaria in Nepal — COMPLETED · PHASE4

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