Malignant Glioma Clinical Trials

158 clinical trials for Malignant Glioma across international registries, including 14 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG) — RECRUITING · PHASE1
• CARv3-TEAM-E T Cells in Glioblastoma — RECRUITING · PHASE1
• Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery — RECRUITING · PHASE1
• Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas — RECRUITING · PHASE1
• Chronic CED of TPT for Recurrent Malignant Glioma — RECRUITING · PHASE1
• Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloud® Device to Treat Malignant Brain Tumors in Pediatric Patients — RECRUITING · PHASE1
• Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma — RECRUITING · PHASE1
• Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial — RECRUITING · PHASE1
• Non-invasive Glioma Characterization Through Molecular Imaging — RECRUITING · NA
• Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma — RECRUITING · PHASE1
• Serial Advanced Magnetic Resonance Imaging Scan for Guidance of Personalized Adaptive Radiotherapy for High Grade Glioma — RECRUITING
• T2 Star Magnetic Resonance Imaging and Biomarker Blood Testing to Predict the Change and Progress of Malignant Gliomas — RECRUITING · NA
• Mapping of Electrical Properties in the Brain — RECRUITING
• Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma — RECRUITING · PHASE1
• Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy — SUSPENDED · PHASE2
• Mind-Body Intervention in Glioma Couples — ACTIVE_NOT_RECRUITING · NA
• Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) — ACTIVE_NOT_RECRUITING · PHASE2
• Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma — ACTIVE_NOT_RECRUITING · PHASE1
• Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations — ACTIVE_NOT_RECRUITING · PHASE2
• Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma — ACTIVE_NOT_RECRUITING · PHASE2
• Fitness and Nutrition in Glioma — ACTIVE_NOT_RECRUITING · NA
• D2C7 for Adult Patients With Recurrent Malignant Glioma — COMPLETED · PHASE1
• PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma — ACTIVE_NOT_RECRUITING · PHASE1
• D2C7-IT With Atezolizumab for Recurrent Gliomas — ACTIVE_NOT_RECRUITING · PHASE1
• Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults — ACTIVE_NOT_RECRUITING · PHASE1
• Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG — ACTIVE_NOT_RECRUITING · NA
• Adoptive Cellular Therapy in Pediatric Patients With High-grade Gliomas — TERMINATED · PHASE1
• Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial) — COMPLETED · PHASE2
• Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma — COMPLETED · PHASE2
• A Pilot Study Using 18F-DOPA PET-guided Radiotherapy in Gliomas — ACTIVE_NOT_RECRUITING
• 9-ING-41 in Patients With Advanced Cancers — ACTIVE_NOT_RECRUITING · PHASE2
• BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas — ACTIVE_NOT_RECRUITING · PHASE1
• Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma — ACTIVE_NOT_RECRUITING · PHASE1
• Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype — ACTIVE_NOT_RECRUITING · PHASE2
• Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma — ACTIVE_NOT_RECRUITING · PHASE1
• Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma — COMPLETED · PHASE2
• 18F-DOPA-PET in Finding Tumors in Patients With Newly Diagnosed Gliomas Undergoing Radiation Therapy — COMPLETED · PHASE2
• Effect H2 Water on QoL of Patients Receiving Radiotherapy for High Grade Gliomas. — ACTIVE_NOT_RECRUITING · PHASE2
• Lerapolturev in Recurrent Malignant Glioma — COMPLETED · PHASE2
• 18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy — COMPLETED · PHASE2
• MK-3475 in Combination With MRI-guided Laser Ablation in Recurrent Malignant Gliomas — COMPLETED · PHASE1
• Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma — COMPLETED · PHASE1
• AMPLIFYing NEOepitope-specific VACcine Responses in Progressive Diffuse Glioma — COMPLETED · PHASE1
• Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial) — COMPLETED · PHASE2
• 18F-DOPA-PET in Planning Surgery in Patients With Gliomas — COMPLETED · PHASE1
• Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme — COMPLETED · PHASE2
• Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas — COMPLETED · PHASE1
• Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial) — COMPLETED · PHASE2
• Psychological Intervention For Brain Tumor Caregivers — COMPLETED · NA
• Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma — COMPLETED · PHASE1

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