Malignant melanoma of skin Clinical Trials

60 clinical trials for Malignant melanoma of skin across international registries, including 25 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Evaluation of training offers within the framework of the Center for Competence Development in Cancer Self-Help (ZfK KSH) — RECRUITING
• Multiperspective Observations of Survivorship After Immune Checkpoint inhibition (MOSAIC): A Mixed-Methods Study on Unmet Needs of Melanoma Survivors and Their Caregivers — RECRUITING
• Application of a Polylactide-Based Skin Substitute in Dermatosurgery to Promote Secondary Wound Healing Following Excision of Precancerous and Malignant Skin Lesions — RECRUITING
• Long-term quality of life and treatment-related side effects in patients with stage III melanoma – a multicenter comparison between adjuvantly treated and untreated patients (Survivorship III) — RECRUITING
• PEF-Adjuvant – Shared Decision-Making for Adjuvant Systemic Therapy in Melanoma: A Multicentre, Prospective, Cluster-Randomised Implementation Study Using a Stepped-Wedge Design — RECRUITING
• Dynamic data acquisition in PET diagnostics: a prospective data collection in clinically indicated examinations — RECRUITING
• Cross-institutional, prospective, open label, single group basket study of combined CRAF and MEK inhibition in advanced-stage malignancies harboring BRAF mutations with impaired kinase activity — RECRUITING
• MR imaging of human brain metabolism using deuterated glucose at 9.4 T — RECRUITING
• Early detection of side effects in patients with metastatic melanoma receiving immune checkpoint inhibitor therapy by investigation of the CD8+ immune infiltrate using [89Zr]Zr-Df-IAB22M2C-PET — RECRUITING
• Identification of predictive and prognostic factors for cell therapy of solid tumors — RECRUITING
• Pilot study on the acquisition of suspicious skin lesions with thermography and photography in patients at the Dermatology Clinic of the University Medical Center in Göttingen — RECRUITING
• Late PET/CT acquisition for improved tissue characterization and assessment of treatment response: prospective data collection in clinically indicated examinations in oncology. — RECRUITING
• Can ChatGPT Serve as a Supportive Tool for Multidisciplinary Tumor Boards? A Single-Center, Retrospective Analysis — RECRUITING
• Automated analysis of whole body FDG PET/CT Data using Machine Learning methods — RECRUITING
• Symptom burden in dermato-oncology - a prospective observational study — RECRUITING
• Investigation of multispectral photoacoustic tomography (MSOT) as an additional method to ultrasound diagnosis in melanoma follow-up patients for differentiation of lymph node metastases to Covid-19 vaccination associated lymphadenopathy — RECRUITING
• Investigation of the BRAF mutation status in the pleural punctate in patients with malignant melanoma, colorectal or lung cancer, that show a BRAF mutation in the primary tumor and the comparison of the result with the conventional cytological / immunohistochemical and molecular cytology findings of the pleural punctate — RECRUITING
• Case register study to capture the efficacy of Ipilimumab and other therapies after treatment with Nivolumab or Pembrolizumab in Ipilimumab naive patients with stage IV or non-resectable stage III metastatic melanoma — RECRUITING
• A Study of MEK162 in NRAS mutated metastatic melanoma patients with brain metastases — RECRUITING
• Immunohistochemical investigation of the expression of biglycan and integrin beta 1 in melanoma as a prognostic marker for progression-free and overall survival — RECRUITING
• Effects of RAF inhibitors for the treatment of melanoma on patients' keratinocytes — RECRUITING
• Endoscopic vs. conventional radical iliacal lympadenectomy for malignant melanoma - a randomized controlled trial — RECRUITING
• Non-invasive imaging of sentinel lymph node with a Multispectral Optoacoustic Tomography (MSOT-Scanner) in patients with malignant melanoma — RECRUITING
• Endoscopic vs. conventional radical inguinal lympadenectomy for malignant melanoma - a randomized controled trial — RECRUITING
• Phase I Study with non-viral jet-injection-genetransfer of a TNF-alpha expressing MIDGE-vector in cutaneous metastases of malignant melanoma — RECRUITING
• Socioeconomic Context of Melanoma Patients in Lower Saxony and Germany — NOT_YET_RECRUITING
• General practitioners´ involvement in oncological aftercare (ACTION) — NOT_YET_RECRUITING
• Reading Study for AI-Segmentation in PET/CT: Ready for Prime Time? — NOT_YET_RECRUITING
• A Prospective Controlled Trial of Large Language Model–Based Simplification of Oncologic PET/CT Reports for Patients with Cancer — NOT_YET_RECRUITING
• Prospective cross-sectional study on occupational UV exposure, risk awareness and preventive measures in patients with malignant melanoma — OTHER
• Intratumoral PH-762 for Cutaneous Carcinoma — ACTIVE_NOT_RECRUITING · PHASE1
• Optimization of polypharmacy in geriatric oncology — OTHER
• Investigation of cognitive dysfunction in patients with advanced skin cancer undergoing systemic therapy — OTHER
• In vivo dermatofluoroscopy to optimize the algorithm for "intelligent measurement" of malignant melanomas. — OTHER
• Whole brain helical tomotherapy with integrated boost for brain metastases in patients with malignant melanoma – a randomized trial — OTHER
• Evaluation of the sunprotection programm "Clever in Sun and Shade" for preschools — OTHER
• EDDA: Explainable Domain-Specific Artificial Intelligence for Dermatopathological Melanoma Detection — A Diagnostic Accuracy Study — OTHER
• End of Life Care - Preferences of Patients with Advanced Skin Cancer — OTHER
• Metastatic Melanoma Patients Under Immunotherapy: Monitoring of Therapeutic Success Using Liquid Biopsy and PET/CT in a Prospective Study — OTHER
• Evaluation of stepwise PET acquisition compared to continuous acquisition — NOT_YET_RECRUITING
• Sentinel lymph node excision in the head and neck area for cutaneous malignancies: clinical evaluation of a hybrid tracer (technetium and indocyanine) versus technetium labeling — OTHER
• Neuroendocrine and psychophysiological effects of the sentinel lymph node excision in melanoma patients under local anesthesia vs. general anesthesia. — OTHER
• Implementation of teledermatologic referrals into general practice - a cluster-randomized controlled trial — OTHER
• COMBI-r – A non-interventional, multi-centric, prospective trial of combined Dabrafenib and Trametinib treatment of advanced melanoma in the real-world setting — OTHER
• Comparison of surgical closure options using standard textbook and online teaching tool FlapFinder in dermatosurgery. — OTHER
• Recording of pain perception in dermatosurgical interventions under local anesthesia — OTHER
• Identification of seborrheic keratoses by dermatofluoroscopy — OTHER
• "Photoacoustic tomography (PAT) in combination with high resolution ultrasound for non-invasive diagnosis of sentinel lymph node in patients with malignant melanoma" — OTHER
• Investigation of the T cell metabolic reprogramming during immunotherapy in oncologic patients — NOT_YET_RECRUITING
• Cinicial trial to assess the two-photon microscope "VertiSCAN" (future "2PM VertiSCAN") in the in vivo and ex vivo diagnostics of melanocytic, mesenchymal and epithelial benign as malignant skin tumors (epidermis and upper cutis) — OTHER

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