Malignant neoplasm of bladder Clinical Trials

80 clinical trials for Malignant neoplasm of bladder across international registries, including 29 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Prognostic value of molecular subtypes in bladder cancer — RECRUITING
• Randomized comparison of oophorectomy or not in conjunction with radical cystectomy in women — RECRUITING
• Partial Cystectomy & Extended Pelvic Lymph Node Dissection With SOC Perioperative Systemic Therapy — RECRUITING · PHASE2
• Evaluation of training offers within the framework of the Center for Competence Development in Cancer Self-Help (ZfK KSH) — RECRUITING
• Search for exosomal biomarkers for urological tumors — RECRUITING
• Molecular Fingerprinting in Cancer Detection — RECRUITING
• Non-interventional, prospective study to evaluate the predictive potential of early CRP kinetics, in particular the CRP flare-response phenomenon, on the efficacy of immunotherapy in advanced urooncological tumors (renal cell carcinoma, urothelial carcinoma). "Prospective Evaluation of the CRP-FLAre phenomenon on Immunotherapy REsponse in Urooncology (FLAIRE)." — RECRUITING
• Patient perspective on follow-up care for bladder cancer: experiences with cystoscopy and acceptance of AI-supported urine cytology — RECRUITING
• The impact of transurethral en bloc resection on the dissemination of circulating tumor cells and tumor DNA in NMIBC compared with conventional TUR-B — RECRUITING
• Comprehensive Outcome Measures and Perioperative Morbidity After Cystectomy — RECRUITING
• Evaluation of One-step Nucleic Acid Amplification (OSNA) for the detection of lymph node metastases in bladder and penile carcinoma — RECRUITING
• Clinical implementation and real-world outcomes of single-port robot-assisted laparoscopic procedures at a university medical centre — RECRUITING
• GUARDIANS-Registry (GenitoUrinary Academic Research Development Initiative and Network) — RECRUITING
• Improvement of the quality of care through standardized documentation — RECRUITING
• Prehabilitation of bladder cancer patients at elevated risk of perioperative mortality to improve outcome after radical cystectomy: Therapy modelling and feasibility study. — RECRUITING
• Molecular biological and cellular characterization of urological tumours tumors for the investigation of tumorigenesis, metastasis and therapy response response to therapy, as well as establishment of an organoid and biobank of urological tumors — RECRUITING
• Influence of the anesthetic procedure on the exosomal micro-RNA signature in patients undergoing radical cystectomy — RECRUITING
• National urothelial carcinoma registry for recording and improving the quality of care across sectors — RECRUITING
• Non-interventional prospective research study by d-uo on intravesical instillation of mitomycin C in non-muscle invasive bladder cancer — RECRUITING
• Prospective clinical trial about quality of life and sexuality following radical cystectomy — RECRUITING
• Fertility Preserving Measures in Young People with Cancer - Ethical and Psychosocial Aspects of Information and Consent — RECRUITING
• Examination of tissue samples of the urogenital tract using optical coherence tomography and other spectrographic means — RECRUITING
• Impact of drugs on survival of patients with non-muscle invasive urothelial carcinoma of the bladder and patients after radical cystectomy. — RECRUITING
• Prospective, randomized, interventional, multi-center, single-blinded phase III clinical trial on the use of en-bloc mucosec-tomy technique (ERBT) or conventional transurethral resection of bladder tumors (TURBT) in patients with first appearance of non-muscle invasive bladder tumors (NMIBC) - EBRUC II trial — RECRUITING
• Value of FGFR alterations on treatment outcomes in bladder cancer: a multicenter collaboration project — RECRUITING
• Prospective evaluation of a preoperative geriatic assessment as predictor of clinical outcome after major urological tumor surgery. — RECRUITING
• Urinary LASP-1 as diagnostic marker for detection of transitional cell carcinoma of the urinary bladder — RECRUITING
• A Phase IIB study of the tetramodal therapy of T2-T4 Nx M0 bladder cancer with hyperthermia combined with chemoradiotherapy following TUR-BT — RECRUITING
• An open-label, randomised, multicentre, phase II study to evaluate the efficacy of chemotherapy with gemcitabine and cisplatin in combination with the EGF receptor antibody panitumumab (GemCisP) versus GemCis in the first-line therapy of locally advanced/metastatic urothelial carcinoma in patients with wild-type HRAS - PURO - AB 23/09 — RECRUITING
• A study comparing three vs six cycles of platinum-based chemotherapy before avelumab in advanced bladder cancer — ACTIVE_NOT_RECRUITING · PHASE2
• Yorkshire screening of urine trial (YORKSURe) — ACTIVE_NOT_RECRUITING
• A study investigating if a new medication, bintrafusp alfa, can reduce the size of urothelial carcinoma, a type of bladder cancer, before surgery to remove the bladder — ACTIVE_NOT_RECRUITING · PHASE2
• Prospective Development and Evaluation of a Non-Invasive, Multimodal, Risk-Adapted Diagnostic Tool for the Detection of Urothelial Carcinoma in an Outpatient Cystoscopy Cohort — NOT_YET_RECRUITING
• Multiple-instance learning for classification of urinary cytology slides: retrospective model development in a pilot cohort and prospective validation — OTHER
• Quality of life after bladder-preserving radiotherapy for bladder cancer — OTHER
• Epidemiology and perioperative outcomes of radical cystectomy in Germany and Denmark: a population-based parallel-cohort study — NOT_YET_RECRUITING
• Prospective validation of membranous NECTIN-4 expression as biomarker to predict enfortumab vedotin + pembrolizumab response in metastatic urothelial cancer — OTHER
• Focused abdominal physiotherapy to reduce postoperative ileus after radical cystectomy — OTHER
• Automated Classification of Urinary Cytology Slides by Artificial Intelligence: Retrospective Development and Prospective Validation of a Multiple-Instance Learning Model — OTHER
• Urinary Peptide Panel to Predict Necessity of Repeated Transurethral Resection of Bladder Tumour — NOT_YET_RECRUITING
• Comparison of Cystectomy and Nephroureterectomy with Alternative Therapeutic Strategies in Patients with Urothelial Carcinoma of the Urinary Bladder and Upper Urinary Tract – Analysis of Clinicopathological Factors and Survival Data. — NOT_YET_RECRUITING
• Optimization of polypharmacy in geriatric oncology — OTHER
• Smoking cessation in patients with urothelial carcinoma has significant and positive effects on quality of life, disease coping, and clinical outcomes. — NOT_YET_RECRUITING
• Transurethral En-Bloc Resection of Urothelial Bladder Carcinoma using combined high-pressure-waterjet-technology and high frequency surgery — OTHER
• Clinical outcomes in non-muscle invasive bladder cancer: A global multisite chart review study — OTHER
• Feasibility of a day clinic for integrative prehabilitation complementary to neoadjuvant tumor treatment in an open group setting — OTHER
• The effect of audio(-visual) distraction on anxiety and pain during outpatient urological procedures — OTHER
• Circulating tumor DNA (ctDNA), circulating cancer cells (CTC), and biomarker evaluation of Nectin4, Trop2, and Her2neu in patients with muscle invasive bladder cancer (MIBC) receiving neoadjuvant chemotherapy (NAC) prior to robotic-assisted radical cystectomy. — NOT_YET_RECRUITING
• Use of wearables for pre- and postoperative monitoring of patients after radical robot-assisted or open cystectomy — NOT_YET_RECRUITING
• Use and acceptance of a psycho-oncological online help for urogenital cancers — OTHER

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