Metastatic Colorectal Cancer Clinical Trials

755 clinical trials for Metastatic Colorectal Cancer across international registries, including 119 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer — RECRUITING · PHASE2
• A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03) — RECRUITING · PHASE3
• Novel Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer — RECRUITING · NA
• Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC) — RECRUITING · PHASE1
• Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer — RECRUITING · PHASE2
• Neoadjuvant Dupilumab and Toripalimab in MSS CRC Subjects With Resectable Liver Metastases — RECRUITING · PHASE1
• A Study to Investigate CEA-PRIT 2.0 in Participants With Metastatic Colorectal Cancer (mCRC) — RECRUITING · PHASE1
• Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer — RECRUITING · PHASE3
• TARGETed Therapy Drug MONITOring in DIGestive Oncology — RECRUITING · NA
• Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation — RECRUITING · PHASE3
• A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors — RECRUITING · PHASE1
• ICE Study: Combination of Irinotecan Plus Cetuximab and Envafolimab as a Rechallenge Regimen in mCRC — RECRUITING · PHASE2
• Fruquintinib Plus Anti-EGFR Antibody for Third-Line Treatment of RAS Wild-Type mCRC — RECRUITING · PHASE2
• Phase 1 Study Of SAR445877 In Combination With FOLFOX6 And Bevacizumab As First-Line Treatment For Microsatellite Stable Metastatic Colorectal Cancer — RECRUITING · PHASE1
• Immunotheray Combined With Simvastatin and Target Therapy and Chemotharepy for Advanced Colorectal Cancer — RECRUITING · PHASE2
• Testing a Functional Precision Medicine Approach to Select Chemotherapy for Metastatic Colorectal Cancer (COSENSE-1) — RECRUITING · PHASE2
• A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC) — RECRUITING · PHASE1
• Primary and Acquired Resistance to Targeted Treatment in BRAF V600E-mutated Metastatic Colorectal Cancer — RECRUITING
• A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer — RECRUITING · PHASE2
• PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma — RECRUITING · PHASE2
• A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer — RECRUITING · PHASE1
• A Clinical Study of Arfolitixorin in Patients With mCRC — RECRUITING · PHASE1
• C6461003 - AN INTERVENTIONAL, PHASE 3, DOUBLE-BLIND, RANDOMIZED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY VERSUS BEVACIZUMAB IN COMBINATION WITH CHEMOTHERAPY IN TREATMENT-NAÏVE PARTICIPANTS WITH METASTATIC COLORECTAL CANCER — RECRUITING · PHASE3
• A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations — RECRUITING · PHASE1
• Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors — RECRUITING · PHASE1
• A FIH, Phase I/IIa, Trial Assessing Feasibility of Administrations of TIL-based Immunotherapy in Patients With Metastatic CRC and PC — RECRUITING · PHASE1
• BBO-11818 in Adult Subjects With KRAS Mutant Cancer — RECRUITING · PHASE1
• Real World Multicenter National Study to Evaluate the Effectiveness and Safety of Biosimilar Bevacizumab Elovie — RECRUITING
• Prospective National Cohort Evaluating Prognostic Factors for Efficacy of Fruquintinib Treatment in Patients With Metastatic Colorectal Cancer — RECRUITING · NA
• Phase II Study of Anti-PD-1/VEGF Bispecific Antibody Ivonescimab in Patients With Previously Treated Metastatic Colorectal Cancer — RECRUITING · PHASE2
• Evaluation of RBS2418 in Patients With Advanced, Metastatic, and Progressive Colorectal Cancer — RECRUITING · PHASE2
• FAPI Molecular Imaging for Diagnosis of the CMS4 Unfavorable Colorectal Cancer Subtype — RECRUITING · NA
• Randomized Controlled Trial of the Effects of Combined Resistance and AerobiC Exercise on Health-related Quality of Life in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer (REACH) — RECRUITING · NA
• JS212 Combination Therapies in Metastatic Colorectal Cancer — RECRUITING · PHASE2
• New Second-Line Combo Therapy for MSS Metastatic Colorectal Cancer — RECRUITING · PHASE2
• Evaluation of a Diagnostic Test to Identify the Best Drugs for Treatment of Metastatic Colorectal Cancer — RECRUITING · NA
• A Comparative Study of Pharmacokinetics, Safety, and Immunogenicity of RPH-030 and Vectibix® in Patients With Metastatic Colorectal Cancer With Wild-type RAS as First-line Therapy in Combination With FOLFIRI — RECRUITING · PHASE1
• Assessing the Efficacy and Safety of ctDNA-driven Selection for Anti-EGFR Retreatment in a Real World Metastatic Colorectal Cancer Patients Cohort (the REalCHALLENGE Study) — RECRUITING
• Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer — RECRUITING · PHASE2
• Fruquintinib in Patients With Metastatic Colorectal Cancer — RECRUITING
• Liposomal Irinotecan With TAS102 and Bevacizumab for Patients With Metastatic Colorectal Cancer — RECRUITING · PHASE2
• Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC — RECRUITING · PHASE2
• Personalized T-Cell Therapy iNeo-Vac-T01 in Advanced Colorectal Cancer — RECRUITING · PHASE1
• Open-label Phase 1b Study of Ulixertinib and Cetuximab or Ulixertinib in Combination With Cetuximab and Encorafenib in Patients With Unresectable or Metastatic Colorectal Cancer Who Have Previously Received EGFR or BRAF-directed Therapy — RECRUITING · PHASE1
• A RANDOMIZED, DOUBLE BLIND, PHASE 3 STUDY OF STANDARD-OF-CARE CHEMOTHERAPY AND BEVACIZUMAB WITH OR WITHOUT INCA33890 IN THE FIRST LINE TREATMENT OF METASTATIC MICROSATELLITE STABLE COLORECTAL CANCER — RECRUITING · PHASE3
• Phase II Study of EMB-01 in Recurrent/Metastatic Colorectal Cancer Patients — RECRUITING · PHASE2
• Continuation of Cetuximab Beyond First-Line Progression in Metastatic Colorectal Cancer — RECRUITING · PHASE3
• 5FU/LV, Irinotecan, Temozolomide and Bevacizumab for MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer. — RECRUITING · PHASE1
• NALIRIFOX Plus Targeted Therapy Versus FOLFOX Plus Targeted Therapy as First-line Treatment for Metastatic Colorectal Cancer — RECRUITING · PHASE3
• AN INTERVENTIONAL, PHASE 3, DOUBLE-BLIND, RANDOMIZED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY VERSUS BEVACIZUMAB IN COMBINATION WITH CHEMOTHERAPY IN TREATMENT-NAÏVE PARTICIPANTS WITH METASTATIC COLORECTAL CANCER — RECRUITING · PHASE3

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