Metastatic Malignant Neoplasm in the Brain Clinical Trials

78 clinical trials for Metastatic Malignant Neoplasm in the Brain across international registries, including 18 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab — RECRUITING · PHASE1
• Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer — RECRUITING · PHASE2
• An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis — RECRUITING · PHASE4
• Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability — RECRUITING · PHASE3
• Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain — RECRUITING · PHASE3
• Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors — RECRUITING · PHASE3
• Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain — RECRUITING · PHASE1
• Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery — RECRUITING · NA
• Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors — RECRUITING · NA
• SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial — RECRUITING · PHASE2
• Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology — RECRUITING
• Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System — RECRUITING · PHASE2
• Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies — RECRUITING · NA
• Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors — RECRUITING · PHASE1
• Advanced Magnetic Resonance Imaging for the Identification of Recurrent Brain Tumors and Radiation Necrosis — RECRUITING · NA
• S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity — RECRUITING · PHASE3
• Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases — RECRUITING · PHASE1
• A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases — RECRUITING · PHASE2
• Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases — ACTIVE_NOT_RECRUITING · PHASE2
• HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases — ACTIVE_NOT_RECRUITING · PHASE1
• Mind-Body Intervention in Glioma Couples — ACTIVE_NOT_RECRUITING · NA
• Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain Metastases — ACTIVE_NOT_RECRUITING · PHASE3
• Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases — ACTIVE_NOT_RECRUITING · PHASE3
• Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers — ACTIVE_NOT_RECRUITING · PHASE1
• Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease — ACTIVE_NOT_RECRUITING · PHASE3
• nTMS in Planning Stereotactic Radiosurgery in Patients With Brain Metastases in the Motor Cortex — ACTIVE_NOT_RECRUITING · NA
• Bevacizumab and Atezolizumab With or Without Cobimetinib in Treating Patients With Untreated Melanoma Brain Metastases — ACTIVE_NOT_RECRUITING · PHASE2
• Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma — ACTIVE_NOT_RECRUITING · PHASE2
• Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer — ACTIVE_NOT_RECRUITING · PHASE1
• Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer — ACTIVE_NOT_RECRUITING · PHASE1
• Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery — TERMINATED · PHASE3
• Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases — ACTIVE_NOT_RECRUITING · PHASE3
• Radiosurgery Before Surgery for the Treatment of Brain Metastases — COMPLETED · PHASE1
• Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases — ACTIVE_NOT_RECRUITING · PHASE2
• Ropidoxuridine and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases — ACTIVE_NOT_RECRUITING · PHASE1
• Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine Tumors — ACTIVE_NOT_RECRUITING · PHASE1
• Utility of Perfusion MRI to Detect Radiation Necrosis in Patients With Brain Metastases — COMPLETED · NA
• Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-200M for the Treatment of Melanoma Brain Metastases — TERMINATED · PHASE1
• Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain Metastases — ACTIVE_NOT_RECRUITING · PHASE1
• Genetic Testing in Guiding Treatment for Patients With Brain Metastases — ACTIVE_NOT_RECRUITING · PHASE2
• Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases — COMPLETED · PHASE2
• Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases — TERMINATED · PHASE1
• Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases — ACTIVE_NOT_RECRUITING · PHASE3
• Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases — COMPLETED · PHASE1
• Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis — ACTIVE_NOT_RECRUITING · PHASE2
• Stereotactic Radiosurgery in Treating Patients With Greater Than 3 Melanoma Brain Metastases — ACTIVE_NOT_RECRUITING · PHASE2
• An Interactive Time-Restricted Diet Intervention (txt4fasting) for Reducing Neurocognitive Decline and Improving Survival in Patients With Brain Metastases From Breast or Lung Cancer — TERMINATED · NA
• Low Dose Ipilimumab With Pembrolizumab in Treating Patients With Melanoma That Has Spread to the Brain — COMPLETED · PHASE2
• Neuropsychological Care for Maintaining Quality of Life After Radiation Therapy in Patients With Brain Metastases — ACTIVE_NOT_RECRUITING · PHASE2
• Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread — COMPLETED · PHASE1

Refine this search