Metastatic Melanoma Clinical Trials

365 clinical trials for Metastatic Melanoma across international registries, including 42 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study — RECRUITING · PHASE2
• Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma — RECRUITING · PHASE2
• A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing — RECRUITING · PHASE1
• Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer — RECRUITING · PHASE1
• Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis — RECRUITING · PHASE1
• Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors — RECRUITING · PHASE1
• Safety and Efficacy of OBX-115 in Advanced Solid Tumors — RECRUITING · PHASE1
• A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, Dedifferentiated Liposarcoma, or Angiosarcoma — RECRUITING · PHASE1
• Intralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma — RECRUITING · PHASE1
• A Trial of AK104 or AK112 in Combination With Axitinib in Patients With Metastatic Mucosal Melanoma — RECRUITING · PHASE1
• A Study to Evaluate Adze1.C in Participants With Metastatic Melanoma — RECRUITING · PHASE1
• Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma. — RECRUITING · PHASE3
• Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain — RECRUITING · PHASE3
• Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors — RECRUITING · PHASE1
• Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types — RECRUITING
• A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel — RECRUITING · PHASE1
• Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study — RECRUITING · PHASE4
• Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors — RECRUITING · PHASE2
• Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain — RECRUITING · PHASE1
• A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer — RECRUITING · PHASE1
• MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma — RECRUITING · PHASE1
• IL-17 Blockade to Decrease irAEs (REPLAY) — RECRUITING · PHASE1
• Cryoablation+Ipilimumab+Nivolumab in Melanoma — RECRUITING · PHASE2
• Physical Activity Directly Before Immunotherapy (Nivolumab and Ipilimumab) in Melanoma — RECRUITING · NA
• ctDNA-guided Addition of Ipilimumab to Patients Receiving Nivolumab and Relatlimab — RECRUITING · PHASE4
• Binimetinib and Encorafenib for the Treatment of Metastatic Melanoma and Central Nervous System Metastases — RECRUITING · PHASE2
• Generation of an Artificial Intelligence Algorithm Based on the Analysis of Melanoma Peri-scar Dermatoheliosis, as a Predictive Factor of Response to Anti-PD-1 — RECRUITING
• Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial — RECRUITING · NA
• GB1211 and Pembrolizumab Versus Pembrolizumab and Placebo in Patients With Metastatic Melanoma and Head and Neck Squamous Cell Carcinoma — RECRUITING · PHASE2
• Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors — RECRUITING · PHASE1
• Consolidative Use of Radiotherapy to Block Oligoprogression in Patients With Metastatic Melanoma — RECRUITING · NA
• Immunotherapy Efficacy and PD-L1 as a Predictive Biomarker in Metastatic Melanoma in Slovenia — RECRUITING · NA
• Efficacy of First-Line Immunotherapy in Metastatic Melanoma in Slovenia and Identification of Predictive Biomarkers — RECRUITING · NA
• Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma — RECRUITING · PHASE1
• A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3 — RECRUITING
• Mirdametinib in Patients With Advanced NF1-mutant Melanoma — RECRUITING · PHASE2
• A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases — RECRUITING · PHASE2
• Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma — RECRUITING · PHASE2
• Interim FDG PET-CT in Melanoma Metastatic Patient's Treated by Anti-PD1 Therapy — RECRUITING · NA
• In Vivo Liquid Biopsy of Melanoma (Cytophone) — RECRUITING · NA
• Precision Radiation of Immune Checkpoint Therapy Resistant Melanoma Metastases — RECRUITING · NA
• Biomarkers in Immunotherapy of Melanoma — RECRUITING · NA
• A Study to Assess the Safety, and Tolerability of Nivolumab + Relatlimab Fixed-Dose Combination (FDC) In Unresectable or Metastatic Melanoma Participants In India — NOT_YET_RECRUITING · PHASE4
• Ibrutinib in Treating Patients With Refractory Metastatic Cutaneous Melanoma — COMPLETED · PHASE2
• Testing the Addition of Navitoclax to the Combination of Dabrafenib and Trametinib in People Who Have BRAF Mutant Melanoma — ACTIVE_NOT_RECRUITING · PHASE1
• Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma — ACTIVE_NOT_RECRUITING · PHASE3
• Tacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic Cancers — ACTIVE_NOT_RECRUITING · PHASE1
• Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery — ACTIVE_NOT_RECRUITING · PHASE2
• Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma — ACTIVE_NOT_RECRUITING · PHASE1
• Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer — ACTIVE_NOT_RECRUITING · PHASE1

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