Monoclonal Gammopathy of Undetermined Significance Clinical Trials

52 clinical trials for Monoclonal Gammopathy of Undetermined Significance across international registries, including 21 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• MGUS/MM Awareness and Genetics Insights Campaign (MAGIC) Screening Study — RECRUITING
• CHAAMP (CHArlotte Advocate MGUS Project) Internal Pilot Study — RECRUITING
• A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma — RECRUITING · PHASE2
• Determine the Frequency of Variants in the GBA/PSAP Genes in Patients With MM or MGUS — RECRUITING
• Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome — RECRUITING
• FAST-M: Prolonged Overnight Fasting and Mediterranean Dietary Intervention for Patients With Multiple Myeloma or Its Precursor Disease — RECRUITING · NA
• Integrative Multi-omics Analysis to Predict Monoclonal Gammopathies Clinical Evolution — RECRUITING
• Observational Prospective Research Study In Monoclonal Gammopathies leadINg to Myeloma — RECRUITING
• A Study Comparing a Plant-Based Diet With Supplements and Placebo in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM) — RECRUITING · NA
• Promoting Diagnosis and Management of AL in Italy (ProDigALIty) — RECRUITING
• Quality of Life in Patients With Asymptomatic Monoclonal Gammopathies — RECRUITING
• Two Biologically and Clinically Distinct Entities: Progressive Versus Stable Multiple Myeloma (MM) Precursor Conditions — RECRUITING
• Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource — RECRUITING
• A Study of Carbon 13-based Deep Labelling of Bone Marrow Cells — RECRUITING
• A Study of a Plant-Based Diet and Dietary Supplements in People With Smoldering Multiple Myeloma (SMM) or Monoclonal Gammopathy of Undetermined Significance (MGUS) — RECRUITING · NA
• Sleep Apnea in Patients With MGUS and MM — RECRUITING
• Whole Body MRI in Oncology — RECRUITING
• Characteristics and Clinical Significance of Gut Microbiota in Patients With Monoclonal Gammopathy — RECRUITING
• The China M-protein Screening Project in First-degree Relatives of Myeloma Patient - The CHAPERONE Study — RECRUITING
• Incidence of paraproteinemic keratopathy in patients with monoclonal gammopathy of undetermined significance, smoldering multiple myeloma und multiple myeloma — RECRUITING
• A Cohort Study of Plasma Cell Disorders (PCDs) in PKUFH — RECRUITING
• Osteoanabolic response to mechanical stimulation in patients with monoclonal gammopathy of undetermined significance — OTHER
• Early Detection of Multiple Myeloma to Fight Cancer Disparities: A Screening and Patient Navigation Program — ACTIVE_NOT_RECRUITING · NA
• Early Detection of Amyloidosis in Monoclonal Gammopathy Using Nuclear Medicine Imaging — NOT_YET_RECRUITING · NA
• Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate Cancer — COMPLETED · PHASE2
• Clonal Hematopoiesis of Immunological Significance — NOT_YET_RECRUITING
• Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma — ACTIVE_NOT_RECRUITING · PHASE2
• Imaging in MGUS, SMM and MM — COMPLETED · PHASE2
• Exploring the Effects of Korean-Style Mediterranean Diet (KORMED) and Physical Activity Measurement in Patients With MGUS/SMM: A Pilot Study — NOT_YET_RECRUITING · NA
• Daratumumab for Polyneuropathy Associated With MGUS — WITHDRAWN · PHASE2
• Iceland Screens, Treats or Prevents Multiple Myeloma — ACTIVE_NOT_RECRUITING · NA
• A Study of a Plant-Based Diet in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM) — ACTIVE_NOT_RECRUITING · NA
• The Development and Pilot Testing of a New MR Imaging Protocol to Quantify Myeloma Disease Burden and Bone Loss — COMPLETED
• Observation of the Incidence and Natural History of MGUS in Patients Undergoing Weight Reduction Surgery — COMPLETED
• Screening to Improve Survival in AL Amyloidosis — COMPLETED
• B-Cell Hematologic Malignancy Vaccination Registry — WITHDRAWN
• Dysregulation of Glutamine Activity in the Pathogenesis of Multiple Myeloma — COMPLETED · NA
• Screening for Monoclonal Gammopathy in Individuals Undergoing Physical Examinations Using iMS-LC Assay Technology. — OTHER
• Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant — COMPLETED · PHASE1
• Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization — COMPLETED · PHASE1
• Isatuximab in Type I Cryoglobulinemia — OTHER · PHASE2
• MGUS, SMM, and MM Patient Experience With Coronavirus 19 (COVID-19) Survey — OTHER
• Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From MGUS and SMM. — TERMINATED
• Natural History Study of Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Myeloma (SMM) — TERMINATED
• Establishment of Genomic, Transcriptomic and Functional Characteristics of Tumor Cells in Hyperinflammatory Hemopathies — NOT_YET_RECRUITING
• Imaging Studies and the Development of Multiple Myeloma — WITHDRAWN · PHASE2
• Genomic and Psychosocial Effects of the 3RP on Patients With MGUS and Smoldering Multiple Myeloma — COMPLETED · NA
• Celecoxib in Preventing Multiple Myeloma in Patients With Monoclonal Gammopathy or Smoldering Myeloma — COMPLETED · PHASE2
• S0309, Repository: Blood/Bone Marrow From Pts. With Myeloma, WM, Amyloidosis, or MGUS. — COMPLETED
• A Study Evaluating the Effects of Siltuximab on the Heart in Patients With Monoclonal Gammopathy of Undetermined Significance, Smoldering Multiple Myeloma, or Indolent Multiple Myeloma — COMPLETED · PHASE1

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