Motor Neuron Disease Clinical Trials

121 clinical trials for Motor Neuron Disease across international registries, including 35 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA) — RECRUITING
• Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers — RECRUITING · NA
• Study of Inherited Neurological Disorders — RECRUITING
• Healing ALS Registry Observational Study (HAROS) — RECRUITING
• Functional Outcomes and Control Using Synchron BCI - Australia — RECRUITING · NA
• DESCRIBE - DZNE - clinical registry study of neurodegenerative disorders — RECRUITING
• Genetic Diagnosis in Inborn Errors of Metabolism — RECRUITING
• INdependence Through Endovascular Neuroprosthetic Technology (INTENT): an Early Feasibility Study — RECRUITING · NA
• Non-invasive BCI-controlled Assistive Devices — RECRUITING · NA
• Functional Outcomes and Control Using Synchron BCI - Canada — RECRUITING · NA
• Impact of Physical Functioning on Patient-Reported Outcomes in ALS Patients at TidalHealth — RECRUITING
• Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq) — RECRUITING
• B-cell depletion for the treatment of patients with amyotrophic lateral sclerosis (ALS) - A Randomized, Double-blind, Placebo controlled Pilot Study in Patients with Amyotrophic Lateral Sclerosis for the Evaluation of Efficacy and Safety of B-Cell Depletion with Rituximab (ABCD) — RECRUITING
• Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures — RECRUITING
• Digital App for Speech & Health Monitoring — RECRUITING
• Effects of Long Term Ventilation Support on the Quality of Life of ALS Patients and Their Families — RECRUITING · NA
• GB-PRIME: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices — RECRUITING · NA
• Clinical characteristics, natural history, health care measures, and the frequency of genetic variants in the genes of SOD1, C9orf72, FUS and TARDBP in patients with sporadic and familial amyotrophic lateral sclerosis (ALS) — RECRUITING
• UAE-PRIME: A Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices — RECRUITING · NA
• Creation of a Clinical Database for the Study of Phenotypic Variability in Motor Neuron Diseases — RECRUITING
• Biomarker-driven Phenotypic Dissection of Amyotrophic Lateral Sclerosis — RECRUITING
• The Study Evaluating the Improvement of Nutritional Status and Frailty With Silkworm Pupa Powder Among Patients With Motor Neuron Disease — RECRUITING · NA
• Use of multispectral optoacoustic tomography (MSOT) in differential diagnostics and longitudinal follow-up of neuropathies — RECRUITING
• Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases — RECRUITING
• ALS Research Collaborative — RECRUITING
• Awareness Detection and Communication in Disorders of Consciousness — RECRUITING · NA
• Emotion Processing Among Patients With ALS — RECRUITING
• Tracking down neuromuscular disorders: in-depth diagnostics and interdisciplinary genotype-phenotype characterization — RECRUITING
• PROSA — A Low-burden High-frequency PROgnostic Digital Speech Biomarker to Improve Future Confirmatory ALS and FTD Trials — RECRUITING
• Registry Study of the Provision of Assistive Devices, Medicines, and Other Healthcare Measures in an Inter-cohort Observation of Patients With ALS, SMA and Other Neurological Diseases. — RECRUITING
• Explore Biomarkers of Motor Neuron Disease/Frontal Dementia Spectrum Disease in China — RECRUITING
• Requirements analysis for a robotic assistive system to support and promote the autonomy of people with neuromuscular diseases — RECRUITING
• Pathophysiology of diaphragm fatigue in patients with Amyotrophic lateral sclerosis — RECRUITING
• Collection of cerebrospinal fluid and performing skin biopsies for obtaining fibroblasts for studies at the DZNE — RECRUITING
• Sensitivity of electromyography and ultrasound of the muscle as diagnostic tools in amyotrophic lateral sclerosis — RECRUITING
• Assessing the effect of Triumeq in amyotrophic lateral sclerosis — ACTIVE_NOT_RECRUITING · PHASE3
• Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS) — ACTIVE_NOT_RECRUITING · PHASE1
• Immersive Virtual Reality in Neuropalliative Care: A Pilot Study in ALS Outpatients — OTHER
• Virtual Peer-to-peer Support Programme for Carers of MND — COMPLETED · NA
• Telehealth in Motor Neurone Disease — COMPLETED · NA
• Novel MRI Biomarkers for Monitoring Disease Progression in ALS — ACTIVE_NOT_RECRUITING
• IC14 for Treatment of Amyotrophic Lateral Sclerosis — WITHDRAWN · PHASE2
• Study of Predictive Factors of Progression of Motor Neurone Disease — COMPLETED
• Kamlanoflast In Amyotrophic Lateral Sclerosis — NOT_YET_RECRUITING · PHASE1
• Development and Test of a Headset for BCI Until Obtaining an Efficient and Comfortable System That Can be Used in Daily Practice by ALS People — ACTIVE_NOT_RECRUITING · NA
• Dose-Escalation, Safety and Pharmacokinetic Study of IC14 in Motor Neurone Disease — COMPLETED · PHASE1
• Safety of Intrathecal Riluzole in Patients With Amyotrophic Lateral Sclerosis — NOT_YET_RECRUITING · PHASE1
• A Safety and Tolerability Study of ILB® in Patients With Amyotrophic Lateral Sclerosis (ALS) — TERMINATED · PHASE2
• A Study to Explore the Role of Gut Flora in ALS — WITHDRAWN
• An Open Label Extension Study of Monepantel in Individuals With Motor Neurone Disease — COMPLETED · PHASE1

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